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  • T73348CCG-2046；化合物 CCG-2046CCG-2046

    CCG-2046 is a chemical inhibitor targeting RGS4, demonstrating an inhibition concentration (IC50) of 4.3 μM for the interaction between RGS4 and Gαo signal.

    价 格：￥电议型 号：T73348产 地：中国大陆

  • T73347BCX-1898；化合物 BCX-1898BCX-1898

    BCX-1898, a selective cyclopentane-derived, orally active influenza virus neuraminidase inhibitor, exhibits antiviral activity by inhibiting the replication of influenza A (H1N1, H3N2, H5N1) and influenza B viruses in MDCK cells, with EC50 values ranging from <0.01 to 21 μM. It demonstrates protective effects in the mouse influenza model.

    价 格：￥电议型 号：T73347产 地：中国大陆

  • T73346SC 34301；化合物 SC 34301Enisoprost；Enisoprost

    SC 34301 (Enisoprost), a potent and orally active prostaglandin E1 (PGE1) analog, significantly enhances survival rates and reduces bacterial translocation in burned mice.

    价 格：￥电议型 号：T73346产 地：中国大陆

  • T73345AP 24149；化合物 AP 24149AP 24149

    AP 24149, a potent dual inhibitor targeting Src and Abl, exhibits IC50 values of 9.1 nM for Src and 3.6 nM for Abl, respectively.

    价 格：￥电议型 号：T73345产 地：中国大陆

  • T73343BAP1-IN-1；化合物 BAP1-IN-1BAP1-IN-1

    BAP1-IN-1 is a catalytic activity inhibitor of BRCA1 associated protein 1 (BAP1), exhibiting an inhibitory concentration (IC50) ranging between 0.1-1 μM.

    价 格：￥电议型 号：T73343产 地：中国大陆

  • T73342Prenderol；化合物 Prenderol2,2-Diethyl-1,3-propanediol；2,2-Diethyl-1,3-propanediol

    Prenderol, a potent central-nervous-system (CNS) depressant, exhibits anticonvulsant activity.

    价 格：￥电议型 号：T73342产 地：中国大陆

  • T73341Quipazine化合物 Quipazine2-(1-哌嗪基)喹啉

    Quipazine, a 5-HT (serotonin) agonist, demonstrates affinity for the 5-HT3R receptor in rats with a Ki value of 1.4 nM, effectively displacing GR65630. It exhibits antiviral activity against SARS-CoV-2, achieving an EC50 of 31.64 μM. Additionally, Quipazine acts as a 5-HT3R agonist in peripheral models, indicating its potential for neurological disease research.

    价 格：￥电议型 号：T73341产 地：中国大陆

  • T7334NP118809；化合物NP11880939-1B4；39-1B4|||1-【4-(二苯甲基)-1-哌嗪基】-3,3-二苯基-1-丙酮

    NP118809 (39-1B4) is a potent N-type calcium channel blocker(IC50 : 0.11 μM).

    价 格：￥电议型 号：T7334产 地：中国大陆

  • T73339Anrikefon；化合物 AnrikefonHSK21542；HSK21542

    Anrikefon (HSK21542) is a kappa opioid receptor agonist with analgesic effect [1] .

    价 格：￥电议型 号：T73339产 地：中国大陆

  • T73338Obtusalin；化合物 ObtusalinObtusalin

    Obtusalin, a triterpenoid initially identified in R. dauricum, exhibits UV absorption at 210 nm and possesses antibacterial properties.

    价 格：￥电议型 号：T73338产 地：中国大陆

  • T73337Articaine；化合物 ArticaineHoe-045 free base；Hoe-045 free base

    Articaine (Hoe-045 free base), an amide anesthetic featuring an ester group, effectively relieves pain by reversibly binding to the α-subunit of the voltage-gated sodium channels located in the nerve´s inner cavity. Furthermore, Articaine mitigates LPS-induced acute kidney injury through the suppression of NF-κB activation and inhibition of the NLRP3 inflammasome pathway.

    价 格：￥电议型 号：T73337产 地：中国大陆

  • T73336Ketotifen；化合物 KetotifenHC 20-511；酮替芬|||HC 20-511

    Ketotifen (HC 20-511) is a second-generation, orally active noncompetitive histamine 1 (H1) receptor antagonist and mast cell stabilizer. It inhibits 6-phosphogluconate dehydrogenase (PGD) in vitro and displays antiviral activity against SARS-CoV-2 and the Influenza virus. Additionally, Ketotifen is utilized in researching autoimmune encephalomyelitis (EAE) and preventing asthma attacks.

    价 格：￥电议型 号：T73336产 地：中国大陆

  • T73335P2X7-IN-2；化合物 P2X7-IN-2P2X7-IN-2

    P2X7-IN-2, a P2X7 receptor inhibitor, effectively suppresses IL-Iβ release, demonstrating an inhibitory concentration (IC50) value of 0.01 nM. This compound is utilized in the study of autoimmunity, inflammation, and cardiovascular disease.

    价 格：￥电议型 号：T73335产 地：中国大陆

  • T73334Larotinib；拉罗替尼Larotinib

    Larotinib is an orally active, potent, and broad-spectrum tyrosine kinase inhibitor (TKI) with an IC50 of 0.6 nM for EGFR.

    价 格：￥电议型 号：T73334产 地：中国大陆

  • T73333OICR12694；化合物 OICR12694JNJ-65234637；JNJ-65234637

    OICR12694 (JNJ-65234637) is an orally active inhibitor of B cell lymphoma 6 (BCL6) [1] .

    价 格：￥电议型 号：T73333产 地：中国大陆

  • T73332BI-685509；化合物 BI-685509BI-685509

    BI-685509 is a potent and orally active sGC activator. BI-685509 restores cyclic guanosine monophosphate (cGMP) and improves functionality of nitric oxide (NO) pathways. BI-685509 can be used in research of chronic kidney disease (CKD) and diabetic kidney disease (DKD) [1] .

    价 格：￥电议型 号：T73332产 地：中国大陆

  • T73331GSK3-IN-3；化合物GSK3-IN-3GSK3-IN-3

    GSK3-IN-3 is a mitochondrial autophagy (mitophagy) inducer and GSK-3 inhibitor (IC50: 3.01 μM) that induces parkin-dependent mitochondrial autophagy. GSK3-IN-3 is non-ATP and non-substrate competitive and neuroprotective against 6-OHDA.

    价 格：￥电议型 号：T73331产 地：中国大陆

  • T73330JAK-IN-24；化合物 JAK-IN-24JAK-IN-24

    JAK-IN-24, a JAK inhibitor, exhibits IC50 values of 0.534 nM and 24 nM in the presence of 4 μM and 1 mM ATP, respectively. Additionally, it effectively inhibits STAT5 phosphorylation induced by PBMC IL-15 with an IC50 of 86.171 nM.

    价 格：￥电议型 号：T73330产 地：中国大陆

  • T7333Pyrvinium pamoate；扑蛲灵Pyrvinium embonate；Pyrvinium embonate|||扑蛲灵

    Pyrvinium pamoate (Pyrvinium embonate) is an old anthelminthic medicine for the treatment of enterobiasis , which re-attracts attention as an anti-cancer drug due to its inhibition of Wnt/β-catenin pathway in some types of cancer.

    价 格：￥电议型 号：T7333产 地：中国大陆

  • T73329MMV676584；化合物 MMV676584MMV676584

    MMV676584 has anti-tuberculosis avtivity. MMV676584 is a novel drug candidate for eumycetoma [1] .

    价 格：￥电议型 号：T73329产 地：中国大陆

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