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  • T6840LFRAX486 HCL(1232030-35-1 free base)；化合物FRAX486FRAX486 HCL(1232030-35-1 free base)

    FRAX486 HCL is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.

    价 格：￥电议型 号：T6840L产 地：中国大陆

  • T68123Oxodipine；奥索地平Oxodipine

    Oxodipine, a dihydropyridine-type calcium antagonist , inhibited KCl-induced aortic contraction in rabbits and reduced cardiac force in less potent rat ventricular test-paper contractions. In rat cultured neonatal ventricular myocytes, Oxodipine reduced L-type Ca currents (I) with an IC of 0.24 μM, and against T-type Ca currents (I) with an IC of 0.41 μM. Oxodipine causes constipation in mice and gingival hyperplasia in dogs.

    价 格：￥电议型 号：T68123产 地：中国大陆

  • T68030Acitemate；阿昔替酯Chinoin 123；Chinoin 123

    Acitemate(Chinoin 123) has an inhibitory effect on atherosclerosis and reduces the permeability of the aorta in rabbits fed a hyperlipidemic diet, which can be used to study atherosclerosis.

    价 格：￥电议型 号：T68030产 地：中国大陆

  • T6792BQ-123；化合物BQ-123BQ123；BQ123

    BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2.

    价 格：￥电议型 号：T6792产 地：中国大陆

  • T67123Methyl 2-methoxy-5-methylbenzoate；化合物 Methyl 2-methoxy-5-methylbenzoateMethyl 2-methoxy-5-methylbenz

    Methyl 2-methoxy-5-methylbenzoate is a useful organic compound for research related to life sciences. The catalog number is T67123 and the CAS number is 63113-79-1.

    价 格：￥电议型 号：T67123产 地：中国大陆

  • T66123H-D-Asp(OtBu)-OH；化合物 H-D-Asp(OtBu)-OHH-D-Asp(OtBu)-OH

    H-D-Asp(OtBu)-OH is a useful organic compound for research related to life sciences. The catalog number is T66123 and the CAS number is 64960-75-4.

    价 格：￥电议型 号：T66123产 地：中国大陆

  • T651234-Chloro-1-naphthol；化合物 4-Chloro-1-naphthol4-Chloro-1-naphthol

    4-Chloro-1-naphthol is a useful organic compound for research related to life sciences. The catalog number is T65123 and the CAS number is 604-44-4.

    价 格：￥电议型 号：T65123产 地：中国大陆

  • T6473Dioscin；薯蓣皂甙CCRIS 4123|||Collettiside III|||Saponin；山药|||CCRIS 4123|||Collettiside III|||Saponin

    Dioscin (Collettiside III) is a saponin with antitumor activities.

    价 格：￥电议型 号：T6473产 地：中国大陆

  • T64123ZIKV-IN-5；化合物 ZIKV-IN-5ZIKV-IN-5

    ZIKV-IN-5 is an acid-stable, low cytotoxic anti-ZIKV agent with an EC50 value of 0.71 μM. ZIKV-IN-5 showed effective inhibition of ZIKV NS5 MTase activity.

    价 格：￥电议型 号：T64123产 地：中国大陆

  • T63123FAK inhibitor 6；化合物 FAK inhibitor 6FAK inhibitor 6

    Compound 26F effectively optimizes enzyme inhibition (IC50 = 28.2 nM) while demonstrating relatively low cytotoxicity (IC50 = 3.32 μM). It induces apoptosis in MDA-MB-231 cells in a dose-dependent manner and efficiently arrests these cells in the G0/G1 phase.

    价 格：￥电议型 号：T63123产 地：中国大陆

  • T62123FNDR-20123；化合物 FNDR-20123FNDR-20123

    FNDR-20123 is the first safe and effective anti-malarial HDAC inhibitor, acting on both Plasmodium falciparum HDAC (IC50: 31 nM) and human HDAC (IC50: 3 nM). FNDR-20123 inhibited HDAC1 (IC50: 25 nM), HDAC2 (IC50: 29 nM), HDAC3 (IC50: 2 nM), HDAC6 (IC50: 11 nM), HDAC8 (IC50: 282 nM) and, at nanomolar concentrations, HDAC3 (IC50: 2 nM). The inhibitor of HDAC subtype III was also observed at nanomolar concentrations.

    价 格：￥电议型 号：T62123产 地：中国大陆

  • T61572FNDR-20123 free base；化合物 FNDR-20123 free baseFNDR-20123 free base

    FNDR-20123 free base, a pioneering and orally administered anti-malarial agent, acts as a Histone Deacetylase (HDAC) inhibitor, displaying potent efficacy with IC50 values of 31 nM for Plasmodium and 3 nM for human HDAC, respectively. It effectively targets both the asexual (IC50=41 nM) and sexual blood stages (IC50=190 nM for male gametocytes) of Plasmodium falciparum. Additionally, FNDR-20123 free base inhibits multiple HDAC isoforms, namely HDAC1, HDAC2, HDAC3, HDAC6, and HDAC8, with respecti

    价 格：￥电议型 号：T61572产 地：中国大陆

  • T61239GAL-021 sulfate；GAL-021 硫酸盐GAL-021 sulfate

    GAL-021 sulfate is a BKCa channel blocker that inhibits the analgesic effects of opioids and is used in the study of respiratory control diseases.

    价 格：￥电议型 号：T61239产 地：中国大陆

  • T61238NAT2-IN-1；化合物 NAT2-IN-1NAT2-IN-1

    NAT2-IN-1 (APA) is a selective inhibitor of the drug metabolism enzyme N-acetyltransferase 2 (NAT2), capable of targeting and eliminating cells with slow NAT2 activity [1].

    价 格：￥电议型 号：T61238产 地：中国大陆

  • T61237hCAIX-IN-6；化合物 hCAIX-IN-6hCAIX-IN-6

    Compounds 6B and 14g showed significant inhibitory effect on tumor related subtype HCA IX with low nanomolar potency, while 6K was effective on HCA XII. Compounds 6B, 14g and 6K can be considered as the leading molecules for the development of future cancer therapeutic drugs based on new mechanisms of action.

    价 格：￥电议型 号：T61237产 地：中国大陆

  • T61236CXCR2 antagonist 7；化合物 CXCR2 antagonist 7CXCR2 antagonist 7

    CXCR2 antagonist 7 (compound 19) is a potent CXCR2 antagonist. CXCR2 antagonist 7 shows potent CXCR2 binding affinity ( IC 50 =0.044 μM) and calcium mobilization ( IC 50 =0.66 μM) [ 1].

    价 格：￥电议型 号：T61236产 地：中国大陆

  • T61235CXCR2 antagonist 5；化合物 CXCR2 antagonist 5CXCR2 antagonist 5

    CXCR2 antagonist 5 (compound 25) is a potent CXCR2 antagonist. CXCR2 antagonist 5 shows potent CXCR2 binding affinity ( IC 50 =0.013 μM) and calcium mobilization ( IC 50 =0.1 μM) [ 1].

    价 格：￥电议型 号：T61235产 地：中国大陆

  • T61234Stemphyperylenol；化合物 StemphyperylenolStemphyperylenol

    Stemphyperylenol exhibits potent antifungal activity against Alternaria solani, a plant pathogen, with a minimum inhibitory concentration (MIC) value of 1.57 μM.

    价 格：￥电议型 号：T61234产 地：中国大陆

  • T61233Penehyclidine hydrochloride；盐酸戊乙奎醚Penequinine hydrochloride；Penequinine hydrochloride

    Penehyclidine hydrochloride (Penequinine hydrochloride) is an?M1?and?M3?antagonist and activates?NF-κB?in lung tissue. Penehyclidine hydrochloride inhibits the release of inflammatory factors and shows anticholinergic properties.

    价 格：￥电议型 号：T61233产 地：中国大陆

  • T61232(Rac)-Upacicalcet；化合物 (Rac)-Upacicalcet(Rac)-Upacicalcet

    (Rac)-Upacicalcet is a racemate of Upacicalcet, which serves as an intravenous calcimimetic agent. Upacicalcet acts by directly targeting calcium-sensing receptors on parathyroid cell membranes, effectively suppressing the release of excessive parathyroid hormone (PTH) and reducing blood PTH levels. This compound holds the potential for researching secondary hyperparathyroidism (SHPT) [1].

    价 格：￥电议型 号：T61232产 地：中国大陆

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