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T61231DDO-02005 free base;化合物 DDO-02005 free baseDDO-02005 free base
DDO-02005 (free base), a potent Kv1.5 potassium channel inhibitor, demonstrates an IC 50 of 0.72 μM. It exhibits effective anti-atrial fibrillation (AF) properties in the CaCl2-ACh AF rat model and anti-arrhythmic activity against aconitine-induced arrhythmias [1].
价 格:¥电议型 号:T61231产 地:中国大陆
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T61230Anticancer agent 74;化合物 Anticancer agent 74Anticancer agent 74
Anticancer agent 74 exhibits moderate anticancer activity with lower selectivity and cytotoxicity compared to doxorubicin towards normal cells [1].
价 格:¥电议型 号:T61230产 地:中国大陆
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T6123Verdinexor;化合物VerdinexorKPT-335;KPT-335
Verdinexor (KPT-335) (KPT-335), a specific XPO1/CRM1 inhibitor, are orally bioavailable.
价 格:¥电议型 号:T6123产 地:中国大陆
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T61123Antibacterial agent 111;化合物 Antibacterial agent 111Antibacterial agent 111
Antibacterial agent 111 (Compound 3) exhibits potent antibacterial activity against B. cereus and K. pneumonia, with MIC values of 3.90 μg/mL and 0.49 μg/mL, respectively. It achieves this antibacterial effect by strongly binding to specific residues of tyrosyl-tRNA synthetase [1].
价 格:¥电议型 号:T61123产 地:中国大陆
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T6067PD 123319;化合物PD123319(S)-(+)-PD 123319|||PD123319;(S)-(+)-PD 123319|||PD123319
PD 123319 ((S)-(+)-PD 123319) is a potent, selective AT2 angiotensin II receptor antagonist.
价 格:¥电议型 号:T6067产 地:中国大陆
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T60316AV123;化合物 AV123AV123
AV123 (compound 12) is a non-cytotoxic RIPK1 inhibitor with IC 50 of 12.12 μM. AV123 blocks the TNF-α-induced necroptotic with EC 50 of 1.7 μM, but not the apoptotic cell death. AV123 can be used in the study of necrotic chronic conditions such as ischemia-reperfusion injury of the brain, heart and kidney, inflammatory diseases, neurodegenerative diseases and infectious diseases [1].
价 格:¥电议型 号:T60316产 地:中国大陆
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T60123Chimmitecan;吉米替康(S)-9-Allyl-10-hydroxycamptothecin;(S)-9-Allyl-10-hydroxycamptothecin|||吉米替康
Chimmitecan ((S)-9-Allyl-10-hydroxycamptothecin) is a potent inhibitor of topoisomerase I and displays outstanding activity in vitro and in vivo.
价 格:¥电议型 号:T60123产 地:中国大陆
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T5395BSJ-03-123;化合物BSJ-03-123BSJ-03-123
BSJ-03-123 is a potent, CDK6-selective small-molecule degrader.
价 格:¥电议型 号:T5395产 地:中国大陆
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T4579Pentagastrin;五肽胃泌素ICI-50123;五肽胃泌素|||ICI-50123
Pentagastrin (ICI-50123) is a synthetic polypeptide that has effects like gastrin when given parenterally, which can cause the secretion and synthesis of salivary proteins.
价 格:¥电议型 号:T4579产 地:中国大陆
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T4411DAMGO TFA (78123-71-4(Free base));化合物DAMGO TFADAMGO TFA (78123-71-4(Free base))
Potent, selective agonist of Mu-opioid receptor. Antinociceptive. Stimulates calcium-activated adenylyl cyclases related cAMP production. Expresses chemokines and chemokine receptors through TGF-beta1. Increases food intake of rats.
价 格:¥电议型 号:T4411产 地:中国大陆
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T413469-Demethyl FR-901235;化合物 9-Demethyl FR-9012359-Demethyl FR-901235
9-Demethyl FR-901235 is a demethyl form of FR-901235, which is an immunoactive substance.
价 格:¥电议型 号:T41346产 地:中国大陆
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T41239Verrucofortine;化合物 VerrucofortineVerrucofortine
Verrucofortine has a wide range of applications in life science related research.
价 格:¥电议型 号:T41239产 地:中国大陆
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T41238Viridicatumtoxin;化合物 ViridicatumtoxinViridicatumtoxin
Viridicatumtoxin has a wide range of applications in life science related research.
价 格:¥电议型 号:T41238产 地:中国大陆
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T41237W146 TFA;化合物 W146 TFAW146 TFA
W146 TFA is a selective sphingosine-1-phosphate receptor 1 ( S1PR1 ) antagonist with an EC 50 value of 398 nM.
价 格:¥电议型 号:T41237产 地:中国大陆
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T41236Z-FY-CHO;化合物 Z-FY-CHOZ-FY-CHO
Z-FY-CHO (Z-Phe-Tyr-CHO) is a specific and potent cathepsin L (CTSL) inhibitor [1] [2].
价 格:¥电议型 号:T41236产 地:中国大陆
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T41235γ-Linolenic acid ethyl ester;化合物 γ-Linolenic acid ethyl esterγ-Linolenic acid ethyl ester
γ-Linolenic acid ethyl ester (Ethyl γ-linolenate) is a leukotriene B 4 receptor 4 (LTB 4 ) antagonist which has a potential anti-inflammatory effect[1].
价 格:¥电议型 号:T41235产 地:中国大陆
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T41234LY 379268 disodium salt;LY 379268 disodium saltLY 379268 disodium salt
LY 379268 disodium salt is a sodium salt of LY 379268, a highly selective group II mGlu receptor agonist.
价 格:¥电议型 号:T41234产 地:中国大陆
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T41233Cis-22a;化合物Cis-22aCis-22a
Cis-22a is a TRPV6 inhibitor (IC50 = 0.32 μM), which exhibits selectivity against related TRPV channels and calcium channels. cis-22a displays antiproliferative effects on T47D human breast cancer cells.
价 格:¥电议型 号:T41233产 地:中国大陆
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T41232GSK 2833503A;GSK 2833503AGSK 2833503A
GSK 2833503A is a potent and selective TRPC6 and TRPC3 antagonist (IC50 = 3-16 nM and 21-100 nM, respectively). GSK 2833503A exhibits >63-fold selectivity over other ion channels, including other TRP channels, CaV1.2, hERG and NaV1.5. GSK 2833503A suppresses angiotensin II or endothelin-1-induced cardiac hypertrophy signaling in HEK293 cellsin vitroand in cardiomyocytes.
价 格:¥电议型 号:T41232产 地:中国大陆