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T16592Propargyl-PEG1-SS-PEG1-propargyl;化合物 T16592Propargyl-PEG1-SS-PEG1-propargyl
Propargyl-PEG1-SS-PEG1-propargyl refers to a cleavable di-functional polyethylene glycol (PEG) linker composed of two units. This specific linker is employed in the synthesis of antibody-drug conjugates (ADCs), where it plays a critical role in linking the antibody to the drug. [1]
价 格:¥电议型 号:T16592产 地:中国大陆
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T16591Propargyl-PEG1-SS-PEG1-PFP ester;化合物 T16591Propargyl-PEG1-SS-PEG1-PFP ester
Propargyl-PEG1-SS-PEG1-PFP ester is a cleavable linker consisting of a 1-unit polyethylene glycol (PEG) backbone, designed for use in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T16591产 地:中国大陆
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T16590Propargyl-PEG1-SS-PEG1-C2-Boc;化合物 T16590Propargyl-PEG1-SS-PEG1-C2-Boc
Propargyl-PEG1-SS-PEG1-C2-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T16590产 地:中国大陆
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T16589Propargyl-PEG1-SS-PEG1-acid;化合物 T16589Propargyl-PEG1-SS-PEG1-acid
Propargyl-PEG1-SS-PEG1-acid is a two-unit polyethylene glycol (PEG) linker that is cleavable and commonly employed in the synthesis of antibody-drug conjugates (ADCs) [1].
价 格:¥电议型 号:T16589产 地:中国大陆
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T16588Propargyl-PEG1-SS-alcohol;化合物 T16588Propargyl-PEG1-SS-alcohol
Propargyl-PEG1-SS-alcohol is a 1-unit PEG ADC linker that is cleavable. It finds application in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T16588产 地:中国大陆
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T16475Pexacerfont化合物PexacerfontBMS-562086
Pexacerfont (BMS-562086) is a selective antagonist of the corticotropin-releasing factor receptor (IC50: 6.1±0.6 nM for the human CRF1 receptor).
价 格:¥电议型 号:T16475产 地:中国大陆
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T16432Pan-RAS-IN-1;化合物Pan-RAS-IN-1Pan-RAS-IN-1
Pan-RAS-IN-1 is an inhibitor of pan-Ras. It disrupts the interaction of Ras proteins and their effectors.
价 格:¥电议型 号:T16432产 地:中国大陆
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T16400OPSS-PEG8-COOH;化合物 T16400OPSS-PEG8-COOH
OPSS-PEG8-COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16400产 地:中国大陆
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T16367NVS-PAK1-1;化合物NVS-PAK1-1NVS-PAK1-1
NVS-PAK1-1 is an effective and selective allosteric PAK1 inhibitor (IC50: 5 nM).
价 格:¥电议型 号:T16367产 地:中国大陆
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T16348NS5806;化合物NS5806NS-5806;NS-5806
NS5806 is an effective potassium current activator. NS5806 slows KV4.3 and KV4.2 current decay in channel complexes containing KChIP2. NS5806 enhances KV4.3/KChIP2 peak current amplitudes (EC50: 5.3 μM).
价 格:¥电议型 号:T16348产 地:中国大陆
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T16344NS-2028;化合物NS-2028NS-2028
NS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor (IC50: 30 nM and 200 nM for basal and NO-stimulated enzyme activity). It is commonly used in the research of nitric oxide signaling pathways. NS-2028 inhibits soluble Guanylyl Cyclase activity in homogenates of mouse cerebellum and neuronal NO synthase (IC50: 17 nM and 20 nM). NS-2028 inhibits 3-morpholino-sydnonimine (SIN-1)-elicited formation of cyclic GMP in human cultured umbilical vein endothelial cells (IC50: 30 nM). NS
价 格:¥电议型 号:T16344产 地:中国大陆
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T16334NMS-P515;化合物 T16334NMS-P515
NMS-P515 is an effective, orally active, and stereospecific PARP-1 inhibitor (Kd: 16 nM and an IC50: 27 nM (in Hela cells)). It has anti-tumor activity.
价 格:¥电议型 号:T16334产 地:中国大陆
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T16320NHS-PEG4-(m-PEG4)3-ester;化合物 T16320NHS-PEG4-(m-PEG4)3-ester
NHS-PEG4-(m-PEG4)3-ester is a PEG-based PROTAC linker utilized for synthesizing PROTACs[1].
价 格:¥电议型 号:T16320产 地:中国大陆
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T1632Amitraz双甲脒BTS-27419|||NSC 324552|||双甲脒
Amitraz (NSC 324552) is a white monoclinic crystals. Melting point 187-189°F (86-87°C). Insoluble in water. Used as an acaricide, insecticide and treatment of demodectic mange in dogs.
价 格:¥电议型 号:T1632产 地:中国大陆
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T16309NH-bis-PEG5;化合物 T16309NH-bis-PEG5
NH-bis-PEG5 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16309产 地:中国大陆
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T16308NH-bis-PEG4;化合物 T16308NH-bis-PEG4
NH-bis-PEG4 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16308产 地:中国大陆
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T16305NH-bis-PEG3;化合物 T16305NH-bis-PEG3
NH-bis-PEG3 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16305产 地:中国大陆
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T16301NH-bis-PEG2;化合物 T16301NH-bis-PEG2
NH-bis-PEG2 is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T16301产 地:中国大陆
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T16251N-Succinimidyl-S-acetylthioacetate;N-丁二酸,S-乙酰基巯基乙二醇酯SATA;SATA|||N-丁二酸,S-乙酰基巯基乙二醇酯
N-Succinimidyl-S-acetylthioacetate (SATA) is a protein modification agent that introduces thiol-groups into protein molecules and adds sulfhydryl groups in a protected form to proteins and other amine-containing molecules for later reaction with sulfhydryl reactive crosslinkers such as Sulfo-SMCC, Sulfo-MBS, etc.
价 格:¥电议型 号:T16251产 地:中国大陆
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T16248N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester);化合物 T16248n-propargyl-peg4-carbonyl-n-bis-peg1-
N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) is a polyethylene glycol (PEG) based linker, employed in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T16248产 地:中国大陆