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T16241N-(NHS-PEG3)-N-bis(PEG3-azide);化合物 T16241N-(NHS-PEG3)-N-bis(PEG3-azide)
N-(NHS-PEG3)-N-bis(PEG3-azide) is a polyethylene glycol (PEG)-based linker commonly utilized for the synthesis of proteolysis targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T16241产 地:中国大陆
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T16240N,N’-Diacetyl-L-cystine;化合物N,N’-Diacetyl-L-cystine(Ac-Cys-OH)2|||DiNAC;(Ac-Cys-OH)2|||DiNAC
N,N´-Diacetyl-L-cystine (DiNAC) is the disulphide dimer of N-acetylcysteine with immunomodulating properties. N,N´-diacetyl-L-cystine also has antiatherosclerotic effects in Watanabe-heritable hyperlipidemic rabbit (WHHL) rabbits. N,N´-diacetyl-L-cystine is also an effective and orally active modulator of contact sensitivity/delayed-type hypersensitivity reactions in rodents.
价 格:¥电议型 号:T16240产 地:中国大陆
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T16237N-Me-N-bis-PEG4;化合物 T16237N-Me-N-bis-PEG4
N-Me-N-bis-PEG4 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16237产 地:中国大陆
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T16209N-Boc-N-bis-PEG5;化合物 T16209N-Boc-N-bis-PEG5
N-Boc-N-bis-PEG5 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16209产 地:中国大陆
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T16200N-Benzyl-N-bis-PEG4;化合物 T16200N-Benzyl-N-bis-PEG4
N-Benzyl-N-bis-PEG4 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16200产 地:中国大陆
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T16199N-Benzyl-N-bis-PEG2;化合物 T16199N-Benzyl-N-bis-PEG2
N-Benzyl-N-bis-PEG2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16199产 地:中国大陆
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T1615LIrbesartan HCl;化合物 T1615LIrbesartan hydrochloride|||BMS186295|||BMS 186295|||BMS-186295;Irbesartan h
Irbesartan is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. It selectively and competitively blocks the binding of angiotensin II to the angiotensin I receptor.
价 格:¥电议型 号:T1615L产 地:中国大陆
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T16151Ms-PEG7-Ms;化合物 T16151Ms-PEG7-Ms
Ms-PEG7-Ms is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16151产 地:中国大陆
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T16150Ms-PEG5-t-butyl ester;化合物 T16150Ms-PEG4-t-butyl ester;Ms-PEG4-t-butyl ester
Ms-PEG5-t-butyl ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16150产 地:中国大陆
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T1615Irbesartan;厄贝沙坦SR-47436|||BMS-186295;厄贝沙坦|||SR-47436|||BMS-186295
Irbesartan (SR-47436) is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.
价 格:¥电议型 号:T1615产 地:中国大陆
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T16149Ms-PEG4-Ms;化合物 T161491,11-Bis(methanesulfonyloxy)-3,6,9-trioxandecane;1,11-Bis(methanesulfonyloxy)-3
Ms-PEG4-Ms is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16149产 地:中国大陆
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T16147Ms-PEG2-C2-Boc;化合物 T16147Ms-PEG2-C2-Boc
Ms-PEG2-C2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16147产 地:中国大陆
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T16146Ms-PEG12-m;化合物 T16146Ms-PEG12-m
Ms-PEG12-m is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16146产 地:中国大陆
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T16145MS-444化合物 T16145BE-34776
MS-444 suppresses the activity of purified smooth muscle myosin light chain kinase (MLCK) (IC50: 10 μM).
价 格:¥电议型 号:T16145产 地:中国大陆
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T16136MRS-1706;化合物MRS-1706MRS-1706
MRS-1706 has Ki values of 1.39, 112, 157, and 230 nM for human A2B, A2A, A1, and A3 receptors respectively. MRS-1706 is an effective and selective adenosine A2B receptor inverse agonist.
价 格:¥电议型 号:T16136产 地:中国大陆
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T16134MRS-1191;化合物 T16134MRS-1191
MRS-1191 is an effective and selective A3 adenosine receptor antagonist (KB: 92 nM, a Ki: 31.4 nM for human A3 receptor and an IC50: 120 nM for CHO cells).
价 格:¥电议型 号:T16134产 地:中国大陆
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T1611Isotretinoin;异维A酸13-cis-Retinoic acid;13-cis-Retinoic acid|||异维A酸
Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promote cell differentiation and apoptosis. Isotretinoin is a naturally-occurring retinoic acid with potential antineoplastic activity. This agent also exhibits immunomodulatory and anti-inflammatory responses and inhibits ornithine decarboxylase, thereby decreasing polyamine synthesis and keratinization.
价 格:¥电议型 号:T1611产 地:中国大陆
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T16009LManaglinat dialanetil;地马格列MB06322|||MB 6322|||CS-917;MB06322|||MB 6322|||CS-917
Managlinat dialanetil (MB06322) is an orally available and potent fructose 1,6-bisphosphatase (FBPase) inhibitor with hypoglycaemic activity for the study of type 2 diabetes.
价 格:¥电议型 号:T16009L产 地:中国大陆
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T15971Mal-NH-ethyl-SS-propionic acid;化合物 T15971Mal-NH-ethyl-SS-propionic acid
Mal-NH-ethyl-SS-propionic acid, a cleavable linker employed for the synthesis of antibody-drug conjugates (ADCs)[1], plays a crucial role in the modulation of drug release from the conjugate.
价 格:¥电议型 号:T15971产 地:中国大陆
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T15864m-PEG3-S-Acetyl;化合物 T15864m-PEG3-S-Acetyl
m-PEG3-S-Acetyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15864产 地:中国大陆