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T14934Cethromycin；化合物 T14934Abbott-195773|||ABT-773|||A-195773；Abbott-195773|||ABT-773|||A-195773
Cethromycin (ABT-773) is an antibiotic of ketolide.
价 格：￥电议型 号：T14934产 地：中国大陆
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T14303Alrizomadlin；化合物AlrizomadlinAPG-115|||AA-115；APG-115|||AA-115
Alrizomadlin (APG-115) is an orally active inhibitor of MDM2 with IC50 of 3.8 nM and Ki of 1 nM, respectively[1]. Alrizomadlin blocks the interaction of MDM2 and p53 and induces cell-cycle arrest and apoptosis in a p53-dependent manner.
价 格：￥电议型 号：T14303产 地：中国大陆
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T14068A-192621；化合物 T14068A-192621
A-192621 is a potent, nonpeptide, orally active and selective endothelin B (ETB) receptor antagonist with an IC50 of 4.5 nM and a Ki of 8.8 nM. A-192621 promotes apoptosis in PASMCs and it also causes elevation of arterial blood pressure and an elevation in the plasma ET-1 level[1][2][3]. The selectivity of A-192621 is 636-fold higher than ETA (IC50 of 4280 nM and Ki of 5600 nM).
价 格：￥电议型 号：T14068产 地：中国大陆
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T14067A-1165442；化合物 T14067A-1165442
A-1165442 is a competitive TRPV1 antagonist. For human TRPV, the IC50 values is 9 nM.
价 格：￥电议型 号：T14067产 地：中国大陆
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T13212TRPA1 Antagonist 1；化合物 T13212TRPA-1 Antagonist 1|||TRPA1 Antagonist 1|||TRPA1 Antagonist 1；TRPA-1 An
TRPA1 Antagonist 1 is an antagonist of TRPA1(IC50: 8 nM) and is a methylene phosphate prodrug which converts to its active parent drug.
价 格：￥电议型 号：T13212产 地：中国大陆
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T13112L1Tat-NR2B9c acetate；化合物Tat-NR2B9c acetateTat-NR2B9c acetate (500992-11-0 Free base)|||NA-1 acetate；Ta
Tat-NR2B9c acetate (NA-1 acetate) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. Tat-NR2B9c acetate disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 μM and 8 μM, respectively. Tat-NR2B9c acetate also inhibits neuronal nitric oxide synthase (nNOS)/PSD-95 interaction, and possesses neuroprotective efficacy.
价 格：￥电议型 号：T13112L1产 地：中国大陆
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T13112LTat-NR2B9c TFA化合物 T13112LNA-1 (TFA)
Tat-NR2B9c TFA is a 20-aa peptide, and acts as an inhibitor of postsynaptic density-95 (PSD-95)(EC50 of 6.7 nM for PSD-95d2), and possesses neuroprotective efficacy.
价 格：￥电议型 号：T13112L产 地：中国大陆
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T13112Tat-NR2B9c；化合物 Tat-NR2B9cTat-NR2Bct|||NA-1；Tat-NR2Bct|||NA-1
Tat-NR2B9c (NA-1) is a postsynaptic density-95 (PSD-95) inhibitor with neuroprotective and antiepileptic effects.Tat-NR2B9c inhibits PSD-95d2, PSD-95d1, and PSD-95, which prevents the activation of NMDA-induced NADPH oxidase in neurons, thereby blocking the production of superoxide, which reduces ischemic injury in the acute phase after stroke.
价 格：￥电议型 号：T13112产 地：中国大陆
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T13073LTaltobulin hydrochloride (228266-40-8 free base)；化合物 T13073LSPA-110 hydrochloride|||Taltobulin hydro
Taltobulin hydrochloride is a synthetic analogue of the tripeptide hemiasterlin, is a potent agent of antimicrotubule that circumvents P-glycoprotein-mediated resistance in vitro and in vivo.
价 格：￥电议型 号：T13073L产 地：中国大陆
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T13073Taltobulin trifluoroacetate化合物 T13073HTI-286 trifluoroacetate|||SPA-110 trifluoroacetate
Taltobulin trifluoroacetate is a synthetic analogue of the tripeptide hemiasterlin, is a potent agent of antimicrotubule that circumvents P-glycoprotein-mediated resistance in vitro and in vivo.
价 格：￥电议型 号：T13073产 地：中国大陆
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T12912Sigma-1 receptor antagonist 3；化合物Sigma-1 receptor antagonist 3Sigma-1 receptor antagonist 3
Sigma-1 receptor antagonist 3 is a more potent and selective antagonist of Sigma-1 (σ1) receptor (Ki = 1.14 nM) than σ2 receptor(Ki = 1239 nM). Sigma-1 receptor antagonist 3 inhibits Human Ether-a-go-go-Related Gene (hERG, IC50 = 1.54 μM)
价 格：￥电议型 号：T12912产 地：中国大陆
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T12911Sigma-1 receptor antagonist 2；化合物Sigma-1 receptor antagonist 2Sigma-1 receptor antagonist 2
Sigma-1 receptor antagonist 2 is a more potent and selective antagonist of sigma 1 receptor (σ1 R, Ki = 3.88 nM) than σ2 receptor (Ki = 1288 nM).
价 格：￥电议型 号：T12911产 地：中国大陆
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T12910Sigma-1 receptor antagonist 1；化合物Sigma-1 receptor antagonist 1Sigma-1 receptor antagonist 1
Sigma-1 receptor antagonist 1 is an effective and selective antagonist of sigma-1 receptor. Sigma-1 receptor antagonist 1 exhibits antineuropathic pain activity and can be used in the treatment of neuropathic pain studies.
价 格：￥电议型 号：T12910产 地：中国大陆
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T1245031,5-Bis(4-hydroxy-3-methoxyphenyl)penta-1,4-diene；化合物 1,5-Bis(4-hydroxy-3-methoxyphenyl)penta-1,4-di
1,5-Bis(4-hydroxy-3-methoxyphenyl)penta-1,4-diene is a useful organic compound for research related to life sciences and the catalog number is T124503.
价 格：￥电议型 号：T124503产 地：中国大陆
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T12378LCA-170；化合物 T12378LPD-1-IN-1；PD-1-IN-1
PD-1-IN-1 is a programmed cell dealth-1inhibitor. PD-1-IN-1 can be used as an immune modulator.
价 格：￥电议型 号：T12378L产 地：中国大陆
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T12222Nifedipine-d6；硝苯地平 D6Nifedipine D6|||BAY-a-1040 D6；硝苯地平 D6|||Nifedipine D6|||BAY-a-1040 D6
Nifedipine D6 is deuterium labeled nifedipine which is a potent blocker of calcium channel.
价 格：￥电议型 号：T12222产 地：中国大陆
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T11606ICA-105665；化合物 T11606PF-04895162；PF-04895162
ICA-105665 (PF-04895162) is a potent and orally active neuronal Kv7.2/7.3 and Kv7.3/7.5 potassium channels opener. ICA-105665 had low cytotoxic potential in human hepatocytes but inhibited liver mitochondrial function and bile salt export protein (BSEP) transport (IC50 of 311 μM). ICA-105665 can penetrate the central nervous system (CNS) and has antiseizure effects[1][2][3][4].
价 格：￥电议型 号：T11606产 地：中国大陆
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T1146Nifedipine；硝苯地平BAY-a-1040|||Procardia XL|||Procardia|||Adalat；BAY-a-1040|||Procardia XL|||Procardia|
Nifedipine (Procardia) is a dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents.
价 格：￥电议型 号：T1146产 地：中国大陆
