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T1746LY-2584702 tosylate salt；化合物LY2584702 tosylateLY2584702 tosylate；LY2584702 tosylate
LY-2584702 tosylate salt is a selective, ATP-competitive p70S6K inhibitor, used in trials studying the treatment of cancer.
价 格：￥电议型 号：T1746产 地：中国大陆
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T17446Aminooxy-PEG-OH (MW 2000)；化合物 T17446Aminooxy-PEG-OH (MW 2000)
Aminooxy-PEG-OH (MW 2000) serves as a PEG-based PROTAC linker for the synthesis of PROTACs[1].
价 格：￥电议型 号：T17446产 地：中国大陆
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T1734LRizatriptan化合物 T1734LMK 462 free base|||Risatriptan
Rizatriptan is an agonist of the serotonin-1b and serotonin-1d receptor.
价 格：￥电议型 号：T1734L产 地：中国大陆
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T173469-Decyn-1-ol；化合物 T173469-Decyn-1-ol
9-Decyn-1-ol is an alkyl/ether-based PROTAC linker suitable for synthesizing PROTACs. It serves as a conjugation agent to combine GDC-0068 and Lenalidomide, resulting in the formation of INY-03-041. INY-03-041 is a potent and highly selective pan-Akt degrader that operates through the PROTAC mechanism. It effectively inhibits Akt1, Akt2, and Akt3 with IC50 values of 2.0 nM, 6.8 nM, and 3.5 nM, respectively[1].
价 格：￥电议型 号：T17346产 地：中国大陆
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T17255WJ460；化合物WJ460WJ460
WJ460 is an effective inhibitor of myoferlin. WJ460 exerts anti-metastatic activity in breast cancer cells.
价 格：￥电议型 号：T17255产 地：中国大陆
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T17246VU0529331；化合物 T17246VU0529331
VU0529331 is a modestly selective non-GIRK1-containing G protein-gated, inwardly-rectifying, potassium channel activator (EC50s: 5.1 μM and 5.2 μM for GIRK2 and GIRK1/2 in HEK293 cells, respectively). It is also effective on the GIRK4 homomeric channel.
价 格：￥电议型 号：T17246产 地：中国大陆
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T17245VU0467485化合物 T17245AZ13713945
VU0467485 is a potent and selective muscarinic acetylcholine receptor 4 positive allosteric modulator. VU0467485 potentiates the activity of ACh at M4 (EC50s: 26.6 nM and 78.8 nM at the rat and human M4 receptors, respectively). VU0467485 displays selectivity for M4 over human and rat M1/2/3/5.
价 格：￥电议型 号：T17245产 地：中国大陆
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T17244VU0467154；化合物VU0467154VU0467154
VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor.
价 格：￥电议型 号：T17244产 地：中国大陆
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T17243VU0463271；化合物VU0463271N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetami
VU0463271 (N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide) is a potent and selective antagonist of the neuronal-specific potassium-chloride cotransporter 2 (KCC2), with an IC50 of 61 nM and >100-fold selectivity versus the closely related Na-K-2Cl cotransporter 1 (NKCC1) and no activity in a larger panel of GPCRs, ion channels, and transporters.
价 格：￥电议型 号：T17243产 地：中国大陆
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T17224VER-246608；化合物VER-246608VER-246608
VER-246608 is an effective and ATP-competitive inhibitor of pyruvate dehydrogenase kinase (IC50s: 35 nM, 40 nM, 84 nM, and 91 nM for PDK-1, PDK-3, PDK-2, and PDK-4, respectively).VER-246608 disrupts Warburg metabolism and induces context-dependent cytostasis in cancer cells. Consistent with a PDK mediated MOA, VER-246608 increased pyruvate dehydrogenase complex (PDC) activity, oxygen consumption and attenuated glycolytic activity. VER-246608 was found to potentiate the activity of doxorubicin.
价 格：￥电议型 号：T17224产 地：中国大陆
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T17210L1(3R,6R)-Vaborbactam(3R,6R)-法硼巴坦(3R,6R)-RPX7009|||(3R,6R)-Vaborbactam (Iso-1360457-46-0)
(3R,6R)-Vaborbactam ((3R,6R)-Vaborbactam (Iso-1360457-46-0)) is a cyclic boronic acid pharmacophore β-lactamase inhibitor with potential antimicrobial activity. (S)-Vamicamide ((S)-Vamicamide (Iso-132373-81-0)) is a novel anticholinergic compound.
价 格：￥电议型 号：T17210L1产 地：中国大陆
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T17210LVaborbactam ammonium salt；法硼巴坦铵盐RPX7009 ammonium salt|||Vaborbactam ammonium salt（1360457-46-0 Free
Vaborbactam ammonium salt is a β-lactamase inhibitor that restores carbapenem activity against KPC-producing strains and is often used in conjunction with other drugs to study fungal infections.
价 格：￥电议型 号：T17210L产 地：中国大陆
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T1720LAmfenac；化合物 T1720LNSC309467|||NSC-309467|||NSC 309467；NSC309467|||NSC-309467|||NSC 309467
Amfenac promotes apoptosis in ARPE-19 cell culture.
价 格：￥电议型 号：T1720L产 地：中国大陆
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T17189U-46619；化合物U-466199,11-Methanoepoxy PGH2；9,11-Methanoepoxy PGH2
U-46619 is an effective thromboxane A2 (TXA2) agonist and a thromboxane A2 analog (endoperoxide), capable of inducing contraction in the aortic smooth muscle (SM) of mice with a myosin light chain 9 (Myl9) gene deletion.
价 格：￥电议型 号：T17189产 地：中国大陆
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T17186TY-51469；化合物TY-51469TY-51469
TY-51469 is an inhibitor of chymase (IC50s for simian and human chymases: 0.4 and 7.0 nM, respectively).
价 格：￥电议型 号：T17186产 地：中国大陆
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T17147TPOP146化合物 T17147TPOP 146|||TPOP-146|||TPOP146
TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor (Kd: 134 nM and 5.02 μM for CBP and BRD4).
价 格：￥电议型 号：T17147产 地：中国大陆
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T17146TPO agonist 1；化合物 T17146TPO agonist 1
TPO agonist 1 is a thrombopoietin agonist. It would be useful as promoters of thrombopoiesis and megakaryocytopoiesis to treat thrombocytopenia.
价 格：￥电议型 号：T17146产 地：中国大陆
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T17046Tetra(cyanoethoxymethyl) methane；化合物 T17046Tetra(cyanoethoxymethyl) methane
Tetra(cyanoethoxymethyl) methane is an alkyl chain-derived PROTAC linker suitable for synthesizing PROTACs[1].
价 格：￥电议型 号：T17046产 地：中国大陆
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T17026LTecovirimat hydrate化合物 T17026LST246|||ST 246|||ST-246|||SIGA 246|||SIGA246|||SIGA-246
Tecovirimat,(ST-246, SIgA-246) is an inhibitor of p37 envelope proteins used to treat smallpox infection. Tecovirimat is an antiviral drug that is active against orthopoxviruses such as smallpox and is currently undergoing clinical trials. Its role is to prevent disease by blocking the cellular transmission of the virus.
价 格：￥电议型 号：T17026L产 地：中国大陆
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T17026Tecovirimat特考韦瑞ST-246|||特考韦瑞
Tecovirimat is a core protein cysteine protease inhibitor potentially for treatment of smallpox infection.Tecovirimat is a novel antiviral potent and selective activity against multiple orthopoxviruses (EC50: about 10 nM). that inhibits the egress of orthopoxviruses by targeting viral p37 protein orthologs.Tecovirimat has shown efficacy in all small animal and nonhuman primate prophylaxis and therapeutic efficacy models of poxvirus-induced disease tested to date.
价 格：￥电议型 号：T17026产 地：中国大陆
