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T15446GT 949;化合物GT 949GT 949
GT 949 is a selective excitatory positive allosteric modulator of amino acid transporter-2 (EAAT2) (EC50: 0.26 nM).
价 格:¥电议型 号:T15446产 地:中国大陆
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T15404GNE-6468;化合物 T15404GNE-6468
GNE-6468 is a potent and selective agonist of RORγ(RORc) (EC50: 13 nM for HEK-293 cell).
价 格:¥电议型 号:T15404产 地:中国大陆
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T15398GNE-0946;化合物 T15398GNE-0946
GNE-0946 is a potent and selective agonist of RORγ (EC50: 4 nM for HEK-293 cell).
价 格:¥电议型 号:T15398产 地:中国大陆
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T15346FR-190809;化合物 T15346FR-190809
FR-190809 is a nonadrenotoxic and orally efficacious inhibitor of acyl-CoA:cholesterol O-acyltransferase (ACAT) (IC50: 45 nM).
价 格:¥电议型 号:T15346产 地:中国大陆
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T15246Esaxerenone;艾沙利酮XL-550|||CS-3150;艾沙利酮|||XL-550|||CS-3150
Esaxerenone (XL-550) is a highly potent and selective non-steroidal antagonist of the mineralocorticoid receptor.
价 格:¥电议型 号:T15246产 地:中国大陆
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T15218EN460;化合物 T15218EN460
EN460 is an inhibitor of endoplasmic reticulum oxidation 1 (ERO1) and interacts selectively (IC50: 1.9 uM) with the reduced, active form of ERO1α and prevents its reoxidation.
价 格:¥电议型 号:T15218产 地:中国大陆
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T15199Edicotinib;化合物EdicotinibJNJ-527|||JNJ-40346527;JNJ-527|||JNJ-40346527
Edicotinib (JNJ-527) is a brain penetrant and orally active inhibitor of the colony-stimulating factor-1 receptor (IC50: 3.2 nM). It shows less inhibitory effects on KIT and FLT3 (IC50: 20 nM and 190 nM). It has the potential for Alzheimer´s disease and rheumatoid arthritis treatment.
价 格:¥电议型 号:T15199产 地:中国大陆
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T15196EC23;化合物EC23BASF-46928|||AGN 190205;BASF-46928|||AGN 190205
EC23 (AGN 190205) is a stable synthetic retinoid analogue. It is also induces neuronal differentiation.
价 格:¥电议型 号:T15196产 地:中国大陆
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T1517LBenserazide;化合物 T1517LRo-44602|||Ro44602|||Ro 44602|||Serazide;Ro-44602|||Ro44602|||Ro 44602|||Seraz
Benserazide is an inhibitor of dopa decarboxylase. It is often given with levodopa in the treatment of Parkinson´s to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose.
价 格:¥电议型 号:T1517L产 地:中国大陆
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T1517Benserazide hydrochloride;盐酸苄丝肼Benserazide HCl|||Serazide|||Ro 4-4602;Benserazide HCl|||盐酸苄丝肼|||Sera
Benserazide hydrochloride (Ro 4-4602) is a peripherally-acting L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.
价 格:¥电议型 号:T1517产 地:中国大陆
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T15146DNA2 inhibitor C5;化合物DNA2 inhibitor C5DNA2 inhibitor C5
DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM). DNA2 inhibitor C5 inhibits nuclease, DNA dependent ATPase, helicase, and DNA binding activities of DNA2.
价 格:¥电议型 号:T15146产 地:中国大陆
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T1512Rizatriptan benzoate;苯甲酸利扎曲坦MK-462 Benzoate;苯甲酸利扎曲坦|||MK-462 Benzoate
Rizatriptan benzoate (MK-462 Benzoate) selectively binds to and activates serotonin (5-HT) 1B receptors and 5-HT 1D receptors providing relief of migraine headaches.
价 格:¥电议型 号:T1512产 地:中国大陆
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T15113Diazepinomicin;化合物 T15113TLN-4601|||BU 4664L|||ECO-4601;TLN-4601|||BU 4664L|||ECO-4601
Diazepinomicin is a secondary metabolite produced by Micromonospora sp. It inhibits the EGF-induced Ras-ERK MAPK signaling pathway and induces apoptosis. Diazepinomicin also is an anti-tumor agent for K-Ras mutant models.
价 格:¥电议型 号:T15113产 地:中国大陆
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T15046Dabigatran ethyl ester;达比加群乙酸乙酯Dabigatran (ethyl ester)|||Dabigatran ethyl ester;Dabigatran (ethyl e
Dabigatran ethyl ester (Dabigatran (ethyl ester)) is an emerging oral anticoagulant and it also is a direct inhibitor of thrombin activity.
价 格:¥电议型 号:T15046产 地:中国大陆
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T15025LCY5 triethylamine saltCY5三乙胺盐CY5 triethylamine salt(146368-11-8 Free base)
CY5 triethylamine salt is a water-soluble dye, Excitation (nm):649, Emission (nm): 670.
价 格:¥电议型 号:T15025L产 地:中国大陆
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T14998Copanlisib dihydrochloride;库潘尼西盐酸BAY 80-6946 dihydrochloride;库潘尼西盐酸|||BAY 80-6946 dihydrochloride
Copanlisib dihydrochloride (BAY 80-6946 dihydrochloride) is an ATP-competitive pan-class I PI3K inhibitor (IC50s: 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kα, PI3Kδ, PI3Kβ and PI3Kγ). Copanlisib dihydrochloride has superior antitumor activity and it also has more than 2,000-fold selectivity against other lipid and protein kinases, except for mTOR.
价 格:¥电议型 号:T14998产 地:中国大陆
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T14946Ch55;化合物Ch55Ch-55|||CH 55|||3,5-Di-tert-butylchalcone;Ch-55|||CH 55|||3,5-Di-tert-butylchalcone
Ch55 (3,5-Di-tert-butylchalcone) is an effective inducer of the differentiation of HL60 cells (EC50 = 200 nM) and shows high affinity with RAR-α and RAR-β receptors. Ch55 can be used in studies about cancer.
价 格:¥电议型 号:T14946产 地:中国大陆
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T14930Ceralifimod化合物 T14930ONO-4641
Ceralifimod (ONO-4641) is a potent agonist for sphingosine 1-phosphate receptors 1 and 5 (EC50s: 27.3, 334 pM for human S1P receptor 1 and 5).
价 格:¥电议型 号:T14930产 地:中国大陆
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T14923Cefpiramide sodium头孢匹胺钠头孢匹胺钠|||SM-1652|||Wy-44635
Cefpiramide sodium (SM-1652; Wy-44635) is a Pseudomonas-active cephalosporin. It has a broad spectrum of antibacterial activity.
价 格:¥电议型 号:T14923产 地:中国大陆
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T1485Methotrexate;甲氨蝶呤NCI-C04671|||WR19039|||Amethopterin|||CL14377;NCI-C04671|||WR19039|||Amethopterin||
Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR. Methotrexate has antimetabolic, antitumor, and immunosuppressive activities, and is commonly used in rheumatoid arthritis and various tumors.
价 格:¥电议型 号:T1485产 地:中国大陆