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T15826Lometrexol；洛美曲索LY 264618|||DDATHF；LY 264618|||DDATHF
Lometrexol (LY 264618), an antipurine Antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol can further inhibit de novo purine synthesis, causing abnormal cell proliferation and Apoptosis, even cell cycle arrest. Lometrexol has anticancer activity. Lometrexol also is a potent human Serine hydroxymethyltransferase1/2 (hSHMT1/2) inhibitor.
价 格：￥电议型 号：T15826产 地：中国大陆
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T15771Lobaplatin；络铂D-19466；D-19466|||络铂
Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe. Lobaplatin (D-19466) is a third-generation platinum anti-neoplastic agent which shows activity for a variety of tumour types and is a promising antitumour chemotherapeutic agent[1][2]. It is a platinum complex with DNA alkylating activity.
价 格：￥电议型 号：T15771产 地：中国大陆
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T15746Lexibulin dihydrochloride；化合物 T15746CYT-997 dihydrochloride；CYT-997 dihydrochloride
Lexibulin 2Hcl is an effective tubulin polymerization inhibitor (IC50: 10-100 nM in cancer cell lines). It also has potent cytotoxic and vascular disrupting activity in vitro and in vivo.
价 格：￥电议型 号：T15746产 地：中国大陆
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T15729LDN-91946；化合物LDN-91946LDN-91946
LDN-91946 is an effective and selective inhibitor of ubiquitin C-terminal hydrolase-L1 (UCH-L1) (Ki = 2.8 μM).
价 格：￥电议型 号：T15729产 地：中国大陆
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T15646KBU2046；化合物KBU2046KBU2046
KBU2046 is an orally administered compound that inhibits cell motility and invasion, effectively suppressing cancer metastasis and extending lifespan. This compound uniquely targets and binds to chaperone heterocomplexes, selectively modifying the interaction of client proteins involved in motility regulation, while avoiding the characteristics typical of classical HSP90 inhibitors.
价 格：￥电议型 号：T15646产 地：中国大陆
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T15624JNJ-64619178；化合物JNJ-64619178JNJ-64619178
JNJ-64619178 is a selective, orally active, and pseudo-irreversible inhibitor of protein arginine methyltransferase 5 (IC50: 0.14 nM). It has effective activity In lung cancer.
价 格：￥电议型 号：T15624产 地：中国大陆
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T15622JNJ-54175446；化合物 JNJ-54175446JNJ-5446；JNJ-5446
JNJ-54175446 (JNJ-5446) is a CNS-permeable and selective P2X7 receptor antagonist that attenuates the release of IL-1β/IL-18 from microglia, and may be used in the study of depression.
价 格：￥电议型 号：T15622产 地：中国大陆
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T15619JNJ-46778212；化合物 JNJ-46778212VU 0409551；VU 0409551
JNJ-46778212 (VU 0409551) is a selective and potent mGlu5 allosteric modulator (EC50: 260 nM) for the study of neurodissection.
价 格：￥电议型 号：T15619产 地：中国大陆
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T15618JNJ-46281222；化合物 T15618JNJ-46281222
JNJ-46281222 is an metabotropic glutamate (mGlu) 2-selective, highly potent PAM (positive allosteric modulator). It has nanomolar affinity (Kd = 1.7 nM) and a high modulatory potency (pEC50 = 7.71).
价 格：￥电议型 号：T15618产 地：中国大陆
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T1559Betamethasone dipropionate；二丙酸倍他米松Diprolene AF|||SCH 11460|||Betamethasone 17,21-dipropionate|||Dipr
Betamethasone Dipropionate is the 17, 21-dipropionate ester of betamethasone, a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions. Betamethasone dipropionate (SCH 11460) binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in
价 格：￥电议型 号：T1559产 地：中国大陆
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T15546ICA；化合物ICAN-[4-(2-Pyridinyl)-2-thiazolyl]-2-pyridinamine；N-[4-(2-Pyridinyl)-2-thiazolyl]-2-pyridinam
ICA (N-[4-(2-Pyridinyl)-2-thiazolyl]-2-pyridinamine) is a SK channel inhibitor and exhibits antileishmanial activity (IC50: 2.1 ?M).
价 格：￥电议型 号：T15546产 地：中国大陆
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T15469Hematein氧化苏木精Hydroxybrasilein
Hematein inhibits Akt/PKB Ser129 phosphorylation, the Wnt/TCF pathway, and increases apoptosis in lung cancer cells. Hematein is an oxidation product of hematoxylin acted as a dye and it also is an allosteric casein kinase II inhibitor (IC50: 0.74 μM).
价 格：￥电议型 号：T15469产 地：中国大陆
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T15468HEMADO；化合物 T15468HEMADO
HEMADO is a potent and selective agonist of adenosine A3 receptor (Ki: 1.1 nM at the human A3 subtype).
价 格：￥电议型 号：T15468产 地：中国大陆
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T15467Helenalin化合物 T15467Helenalin
Helenalin is a selective inhibitor of transcription factor NF-κB by direct targeting of p65. It is an anti-inflammatory sesquiterpene lactone compound with alkylating activity. Through its ability to target the cysteine sulfhydryl groups in the p65 subunit of NF-κB, helenalin effectively inhibits its DNA binding.
价 格：￥电议型 号：T15467产 地：中国大陆
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T15465HC-070；化合物HC-070HC 070；HC 070
HC-070 is a TRPC5 and TRPC4 antagonist (IC50 = 9.3 nM and 46 nM).
价 格：￥电议型 号：T15465产 地：中国大陆
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T15464HBX 19818；化合物HBX 19818HBX 19818
HBX 19818 is a specific ubiquitin-specific protease 7 (USP7) inhibitor (IC50: 28.1 μM).
价 格：￥电议型 号：T15464产 地：中国大陆
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T15463(Rac)-HAMI 3379；化合物 T15463HAMI 3379；HAMI 3379
HAMI 3379 is a potent and selective antagonist of the Cysteinyl leukotriene (CysLT2) receptor. HAMI 3379 has a protective effect on acute and subacute ischemic brain injury. It also attenuates microglia-related inflammation.
价 格：￥电议型 号：T15463产 地：中国大陆
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T15462Haloxon；哈洛克酮Haloxon
Haloxon is an organophosphorus anthelmintic. Haloxon is used against nematodes of the abomasum and small intestine in ruminants.
价 格：￥电议型 号：T15462产 地：中国大陆
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T15461Halopemide；卤培米特Halopemide
Halopemide is a potent inhibitor of PLD (IC50 = 220 and 310 nM for human PLD1 and PLD2). Halopemid is an antagonist of dopamine receptors. Halopemid can be used in psychotropic research.
价 格：￥电议型 号：T15461产 地：中国大陆
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T1546Nitazoxanide；硝唑尼特NSC 697855；NSC 697855|||硝唑尼特
Nitazoxanide (NSC-697855) is a synthetic benzamide with antiprotozoal activity. Nitazoxanide exerts its antiprotozoal activity by interfering with the pyruvate ferredoxin/flavodoxin oxidoreductase dependent electron transfer reaction.
价 格：￥电议型 号：T1546产 地：中国大陆
