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T16946Streptonigrin；化合物 T16946Bruneomycin；Bruneomycin
Streptonigrin is a natural product produced by Streptomyces flocculus, has both anti-tumor and anti-bacterial activity. Streptonigrin acts as a pan-PAD inhibitor (IC50s: 48.3±34.2 μM, 26.1±0.3 μM, 0.43±0.03 μM, and 2.5±0.4 μM for PAD1, PAD2, PAD3, and PAD4, respectively).
价 格：￥电议型 号：T16946产 地：中国大陆
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T16934SRX246；化合物 T16934SRX246
SRX246 has no interaction at V1b and V2 receptors. SRX246 shows negligible binding at 64 other receptors classes, including 35 G-proteincoupled receptors. SRX246 is a potent and CNS-penetrant vasopressin 1a (V1a) receptor antagonist (Ki=0.3 nM for human V1a).
价 格：￥电议型 号：T16934产 地：中国大陆
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T16919Spirendolol；化合物 T16919S 32-468|||Substance 32468|||Li 32-468；S 32-468|||Substance 32468|||Li 32-468
Spirendolol is an antagonist of β adrenergic receptor.
价 格：￥电议型 号：T16919产 地：中国大陆
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T16863SCH 546738；化合物 T16863SCH 546738
SCH 546738 is an effective and non-competitive CXCR3 antagonist. SCH 546738 bindings to the human CXCR3 receptor is determined (Ki: 0.4 nM) in multiple experiments.
价 格：￥电议型 号：T16863产 地：中国大陆
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T16846Sauristolactam；化合物 T16846Saurolactam；Saurolactam
Sauristolactam inhibits the receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclastogenesis and has the potential to inhibit osteoclast differentiation. Sauristolactam, a natural aristolactam isolated from aerial portions of Saururus Chinensis. Sauristolactam has significant neuroprotective activity against glutamate-induced toxicity in primary cultured rat cortical cells.
价 格：￥电议型 号：T16846产 地：中国大陆
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T16799RS-246204；化合物 T16799RS-246204
RS-246204 is an R-spondin-1 substitute compound. RS-246204 is able to initiate small intestinal organoids without the use of the R-spondin-1 protein.
价 格：￥电议型 号：T16799产 地：中国大陆
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T16797RPR104632；化合物RPR104632RPR104632
RPR104632 is a novel and potent antagonist located at the NMDA glycine site with neuroprotective activity.
价 格：￥电议型 号：T16797产 地：中国大陆
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T16791Rottlerin；粗糠柴苦素Mallotoxin|||NSC 56346|||NSC 94525；Mallotoxin|||NSC 56346|||粗糠柴苦素|||NSC 94525
Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM). Rottlerin causes apoptosis via caspase 3 activation.
价 格：￥电议型 号：T16791产 地：中国大陆
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T16760RK-24466；化合物RK-24466KIN 001-51；KIN 001-51
RK-24466 (KIN 001-51) is a selective and potent inhibitor of Lck, inhibits Lck (64-509) and LckCD isoforms with IC50s of less than 1 and 2 nM, respectively.
价 格：￥电议型 号：T16760产 地：中国大陆
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T16746Rhosin；化合物 T16746Rhosin
Rhosin is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM). Rhosin does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin causes cell apoptosis.
价 格：￥电议型 号：T16746产 地：中国大陆
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T16731Rentiapril racemate；伦唑普利外消旋体(Rac)-SA-446|||SA-446 racemate|||(Rac)-Rentiapril；(Rac)-SA-446|||SA-446
Rentiapril racemate (SA-446 racemate) is the racemate of Rentiapril.Rentiapril racemate has anti-inflammatory activity and may be used in glaucoma research.
价 格：￥电议型 号：T16731产 地：中国大陆
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T1665Daptomycin；达托霉素LY146032；达托霉素|||LY146032
Daptomycin (LY146032) is a cyclic lipopeptide antibiotic that inhibits GRAM-POSITIVE BACTERIA.
价 格：￥电议型 号：T1665产 地：中国大陆
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T16646Propargyl-PEG7-Boc；化合物 T16646Propargyl-PEG7-Boc
Propargyl-PEG7-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T16646产 地：中国大陆
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T16546PK 11195化合物 T16546RP 52028
PK 11195 is a ligand of translocator protein. It targets Leishmania chemotherapy (IC50s of 14.2 μM, 8.2 μM, 3.5 μM for L. amazonensis, L. major and L. braziliensis, respectively).
价 格：￥电议型 号：T16546产 地：中国大陆
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T16519LBIM-46187 4HCl；化合物BIM-46187 4HClPH-064 4HCl；PH-064 4HCl
BIM-46187 4HCl (PH-064 4HCl) is a heterotrimeric G-protein complex inhibitor.
价 格：￥电议型 号：T16519L产 地：中国大陆
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T16519PH-064；化合物PH-064BIM-46187；BIM-46187
PH-064 (BIM-46187) is a heterotrimeric G-protein complex inhibitor.
价 格：￥电议型 号：T16519产 地：中国大陆
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T16504PF-4693627；化合物 T16504PF-4693627
PF-4693627 is an effective and selective microsomal prostaglandin E synthase-1 inhibitor (IC50=3 nM). It is used for the treatment of inflammation caused by osteoarthritis (OA) and rheumatoid arthritis (RA).
价 格：￥电议型 号：T16504产 地：中国大陆
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T16493PF-06465469；化合物 T16493PF-06465469
PF-06465469 is a covalent ITK inhibitor(IC50: 2 nM).
价 格：￥电议型 号：T16493产 地：中国大陆
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T16491PF-06446846 hydrochloride；化合物PF-06446846盐酸盐PF-06446846 hydrochloride
PF-06446846 hydrochloride, an orally active and highly selective inhibitor, targets Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) translation by inducing ribosomal stalling at approximately codon 34, effectively suppressing PCSK9 expression.
价 格：￥电议型 号：T16491产 地：中国大陆
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T16476PF-03654746；化合物PF-03654746PF-03654746
PF-03654746 is a selective antagonist of the histamine H3 receptor. PF-03654746 improves cognitive efficacy and disease-modifying effects in Alzheimer´s disease. PF-03654746 can be used in studies about the treatment of allergic rhinitis.
价 格：￥电议型 号：T16476产 地：中国大陆
