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T18998H-L-Photo-lysine hydrochloride;化合物 T18998H-L-Photo-lysine hydrochloride (1253643-88-7 free base);H-L
H-L-Photo-lysine hydrochloride, a photo-cross-linker, is a diazirine-containing lysine amino acid. It can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells.
价 格:¥电议型 号:T18998产 地:中国大陆
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T18943CY3-SE化合物 T18943Sulfo-Cyanine3 Succinimidyl Ester|||Cy3 NHS Ester
CY3-SE (Sulfo-Cy3 NHS ester) is a reactive dye for the labeling of amino-groups in the soluble proteins, peptides, and oligonucleotides/DNA (Excitation: 555 nm, Emission: 570 nm).
价 格:¥电议型 号:T18943产 地:中国大陆
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T18942LCy5-N3 triethylamine salt;Cy5-N3三乙胺盐Cy5-N3 triethylamine salt(1621101-43-6 free base);Cy5-N3 triethy
Cy5-N3 triethylamine salt is a turnip-based fluorescent dye.CY5-N3 can be used to study cellular imaging.
价 格:¥电议型 号:T18942L产 地:中国大陆
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T18843Thiol-PEG8-alcohol;化合物 T18843HS-PEG8-OH;HS-PEG8-OH
Thiol-PEG8-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18843产 地:中国大陆
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T18743t-Boc-Aminooxy-PEG7-amine;化合物 T18743t-Boc-Aminooxy-PEG7-amine
t-Boc-Aminooxy-PEG7-amine is a polyethylene glycol (PEG) derivative utilized as a PROTAC linker for synthesizing PROTACs[1].
价 格:¥电议型 号:T18743产 地:中国大陆
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T18643PTAD-PEG4-amine;化合物 T18643PTAD-PEG4-amine
PTAD-PEG4-amine is a 4-unit cleavable polyethylene glycol (PEG) linker primarily employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T18643产 地:中国大陆
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T18543Phthalimide-PEG4-MPDM-OH;化合物 T18543Phthalimide-PEG4-MPDM-OH
Phthalimide-PEG4-MPDM-OH, a PROTAC linker with a PEGs composition, has applications in the synthesis of various PROTACs. These PROTACs consist of a linker connecting two distinct ligands: one binds to an E3 ubiquitin ligase, while the other binds to the target protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs selectively induce the degradation of target proteins [1].
价 格:¥电议型 号:T18543产 地:中国大陆
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T1854MS436;化合物MS436MS436
MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains.
价 格:¥电议型 号:T1854产 地:中国大陆
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T18443N-Me-N-bis(PEG4-C2-Boc);化合物 T18443N-Me-N-bis(PEG4-C2-Boc)
N-Me-N-bis(PEG4-C2-Boc) is a PROTAC linker utilizing alkyl and ether functionalities, which is instrumental in PROTAC synthesis. [1]
价 格:¥电议型 号:T18443产 地:中国大陆
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T18432N-(m-PEG4)-N’-(m-PEG4)-O-(m-PEG4)-O’-(propargyl-PEG4)-Cy5;化合物 T18432n-m-peg4-n-m-peg4-o-m-peg4-o-pro
N-(m-PEG4)-N´-(m-PEG4)-O-(m-PEG4)-O´-(propargyl-PEG4)-Cy5 serves as a PEG-based PROTAC linker, facilitating the synthesis of PROTACs[1].
价 格:¥电议型 号:T18432产 地:中国大陆
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T18431N-(m-PEG4)-N’-(m-PEG4)-O-(m-PEG4)-O’-(azide-PEG4)-Cy5;化合物 T18431n-m-peg4-n-m-peg4-o-m-peg4-o-azide-p
N-(m-PEG4)-N´-(m-PEG4)-O-(m-PEG4)-O´-(azide-PEG4)-Cy5 is a polyethylene glycol (PEG) derived linker compound employed in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T18431产 地:中国大陆
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T1843XMD8-92;化合物XMD8-92Extracellular signal regulated kinases|||XMD-8-92|||bFGF|||Inhibitor|||promyelocyt
XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).
价 格:¥电议型 号:T1843产 地:中国大陆
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T18343Methyltetrazine-PEG24-amine;化合物 T18343Methyltetrazine-PEG24-amine
Methyltetrazine-PEG24-amine is a PEG-conjugated PROTAC linker utilized for the synthesis of PROTACs[1].
价 格:¥电议型 号:T18343产 地:中国大陆
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T18243Mal-amido-PEG5-C2-?NHS ester;化合物 T18243Mal-amido-PEG5-C2-?NHS ester
Mal-amido-PEG10-C2-NHS ester is a noncleavable ADC linker, comprising a maleimide group and an NHS ester, which serves as a labeling agent for primary amines (-NH2) found in proteins, amine-modified oligonucleotides, and other amine-containing molecules[1][2].
价 格:¥电议型 号:T18243产 地:中国大陆
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T18143m-PEG12-OH化合物m-PEG12-OHDodecaethylene Glycol Monomethyl Ether
m-PEG12-OH (Dodecaethylene Glycol Monomethyl Ether) is a PEG-based PROTAC linker. m-PEG12-OH can be used in the synthesis of PROTACs. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T18143产 地:中国大陆
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T18043Hydroxy-PEG4-C2-methyl ester;化合物 T18043Hydroxy-PEG4-C2-methyl ester
Hydroxy-PEG4-C2-methyl ester is a PEG-based PROTAC linker employed in PROTAC synthesis[1].
价 格:¥电议型 号:T18043产 地:中国大陆
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T1801SR9243;化合物SR9243SR9243
SR9243, an LXR inverse agonist, can induce LXR-corepressor interaction; shows anticancer activity and selectively targets the lipogenesis and Warburg effect.
价 格:¥电议型 号:T1801产 地:中国大陆
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T1799Caspofungin Acetate;醋酸卡泊芬净L 743873|||Cancidas|||MK 0991|||L 743872;醋酸卡泊芬净|||L 743873|||Cancidas|||MK
Caspofungin Acetate (MK 0991) is the acetate salt of an antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the fungus Glarea lozoyensis. This agent is active against Aspergillus and Candida species.
价 格:¥电议型 号:T1799产 地:中国大陆
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T17943FAK ligand-Linker Conjugate 1;化合物 T17943FAK ligand-Linker Conjugate 1
FAK ligand-Linker Conjugate 1 is a chemical compound designed to facilitate PROTAC-mediated protein degradation. This compound consists of a ligand specifically targeting FAK and a PROTAC linker module, which acts as a recruitment agent for E3 ligases including VHL, CRBN, MDM2, and IAP[1].
价 格:¥电议型 号:T17943产 地:中国大陆
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T17897cIAP1 Ligand-Linker Conjugates 13;化合物 T17897E3 ligase Ligand-Linker Conjugates 43;E3 ligase Ligand-L
cIAP1 Ligand-Linker Conjugates 13, containing an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker, are utilized in the development of SNIPERs[1].
价 格:¥电议型 号:T17897产 地:中国大陆