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T16643Propargyl-PEG6-NH2；化合物 T16643Propargyl-PEG6-NH2
Propargyl-PEG6-NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T16643产 地：中国大陆
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T16574Pregnenolone monosulfate sodium salt；化合物 T165743β-Hydroxy-5-pregnen-20-one monosulfate sodium salt；3
Pregnenolone monosulfate sodium salt is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium salt can protect the brain from cannabis intoxication. Pregnenolone monosulfate sodium salt acts as a signaling-specific inhibitor of the cannabinoid CB1 receptor. Pregnenolone monosulfate sodium salt also inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors.
价 格：￥电议型 号：T16574产 地：中国大陆
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T16543Pironetin；化合物 T16543Pironetin
Pironetin binds to α-tubulin and is an effective inhibitor of microtubule polymerization. It also has cell cycle arrest and antitumor activity. Pironetin is an α/β unsaturated lactone isolated from Streptomyces species.
价 格：￥电议型 号：T16543产 地：中国大陆
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T16478PF-04447943化合物PF-04447943PF 04447943|||Edelinontrine|||PF04447943
PF-04447943 (Edelinontrine) is a potent and selective phosphodiesterase 9A inhibitor with an IC50 of 12 nM, which is 78-fold more selective than that used for other PDE family members (IC50>1000 nM).PF-04447943 exhibits anti-inflammatory activity, attenuates inflammatory responses by inhibiting oxidative stress, inflammation, and modulating T-cell polarization, and may be useful for research on sickle cell anemia.
价 格：￥电议型 号：T16478产 地：中国大陆
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T16443PCS1055 dihydrochloride；化合物 T16443PCS1055 dihydrochloride
PCS1055 dihydrochloride is an effective, selective, and competitive muscarinic M4 receptor antagonist (IC50: 18.1 nM and a Kd: 5.72 nM). PCS1055 dihydrochloride is also a potent AChE inhibitor (IC50 s: 22 nM and 120 nM for electric eel and human AChE, respectively). PCS1055 dihydrochloride inhibits radioligand [3H]-NMS binding to the M4 receptor (Ki: 6.5 nM). PCS1055 dihydrochloride shows >100-fold selectivity over M1-, M3-, and M5-receptors and 30-fold selectivity at the M2 receptor.
价 格：￥电议型 号：T16443产 地：中国大陆
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T16439PC786；化合物 T16439PC786
PC786 shows effective antiviral activity against RSV-A (IC50 <0.09 to 0.71 nM) and RSV-B (IC50, 1.3 to 50.6 nM). PC786 is an inhaled respiratory syncytial virus L protein polymerase inhibitor.
价 格：￥电议型 号：T16439产 地：中国大陆
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T16438PC Biotin-PEG3-azide；化合物 T16438PC Biotin-PEG3-azide
PC Biotin-PEG3-azide is a cleavable three-unit polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker, employed in the synthesis of ADCs[1].
价 格：￥电议型 号：T16438产 地：中国大陆
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T16437PC Biotin-PEG3-alkyne；化合物PC Biotin-PEG3-alkynePC Biotin-PEG3-alkyne
PC Biotin-PEG3-alkyne is an ADC linker, cleavable 3-unit PEG, which can also be used to synthesize antibody drug conjugates (ADCs).
价 格：￥电议型 号：T16437产 地：中国大陆
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T16436PBOX 6；化合物PBOX 6PBOX-6；PBOX-6
PBOX 6 is a pyrrolo-1,5-benzoxazepine (PBOX) compound with anticancer and antitumor activity that inhibits breast cancer cell growth in vitro and selectively induces apoptosis in leukemia cells via c-Jun NH2 terminal kinase-dependent phosphorylation and inactivation of Bcl-2 and Bcl-XL.
价 格：￥电议型 号：T16436产 地：中国大陆
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T16435PBIT；化合物PBITPBIT
PBIT inhibits JARID1B histone demethylase (IC50 of about 3 μM). PBIT also inhibits JARID1A and JARID1C (IC50s of 6 μM and 4.9 μM, respectively). PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (JARID1) enzymes .
价 格：￥电议型 号：T16435产 地：中国大陆
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T16434PAT-048；化合物 T16434PAT-048
PAT-048 is an effective and selective autotaxin inhibitor. PAT-048 reduces dermal fibrosis in vivo. PAT-048 also inhibits IL-6 mRNA expression but displays no effect on autotaxin protein and pulmonary lysophosphatidic acid (LPA) production in the lung fibrosis model. PAT-048 has an IC50 and IC90 of 20 nM and 200 nM for autotaxin in mouse plasma.
价 格：￥电议型 号：T16434产 地：中国大陆
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T16433Pancopride；泮考必利LAS 30451；LAS 30451
Pancopride（LAS 30451） is a novel, orally available, long-acting, selective 5-HT3 receptor antagonist that blocks nitrogen mustard and dacarbazine-induced vomiting.
价 格：￥电议型 号：T16433产 地：中国大陆
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T16432Pan-RAS-IN-1；化合物Pan-RAS-IN-1Pan-RAS-IN-1
Pan-RAS-IN-1 is an inhibitor of pan-Ras. It disrupts the interaction of Ras proteins and their effectors.
价 格：￥电议型 号：T16432产 地：中国大陆
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T16431Pamatolol；氨甲酯心定Pamatolol
Pamatolol is a selective and potent beta-adrenoceptor antagonist that has not shown sympathomimetic activity in ex vivo experiments.
价 格：￥电议型 号：T16431产 地：中国大陆
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T16430Paliroden；化合物PalirodenSR 57667|||SR 57667B；SR 57667|||SR 57667B
Paliroden is a non-peptide compound that can be taken orally and is used for supplementing neuro-nutrition. It stimulates the synthesis of endogenous neurotrophic factors and is employed in the research of neurodegenerative diseases such as Alzheimer´s and Parkinson´s.
价 格：￥电议型 号：T16430产 地：中国大陆
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T1643Penciclovir；喷昔洛韦BRL 39123|||VSA 671；喷昔洛韦|||BRL 39123|||VSA 671
Penciclovir (BRL 39123) is a Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor. In HSV infected cells, penciclovir is phosphorylated by viral thymidine kinase and subsequently converted by cellular kinases into the active metabolite, penciclovir triphosphate, which competitively inhibits viral HSV polymerase by blocking deoxyguanosine triphosphate substrate binding. As a result, herpes viral DNA synthesis and replication are selectively inhibited.
价 格：￥电议型 号：T1643产 地：中国大陆
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T16427Padsevonil；帕塞沃尼UCB-0942|||UCB1415943-000；UCB-0942|||UCB1415943-000
Padsevonil (UCB-0942) is a potential GABA A receptor orthosteric modulator with antiepileptic activity for the treatment of epilepsy.
价 格：￥电议型 号：T16427产 地：中国大陆
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T16377Odiparcil；化合物 T16377SB-424323；SB-424323
Odiparcil is an orally active beta-d-thioxyloside analog. Odiparcil is an indirect thrombin inhibitor that exerts its anticoagulant effect through activation of antithrombin II (heparin cofactor II). It also has an antithrombotic activity associated with a reduced risk of adverse bleeding events.
价 格：￥电议型 号：T16377产 地：中国大陆
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T16343NRC-2694；化合物NRC-2694NRC-2694
NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and anti-proliferative properties.
价 格：￥电议型 号：T16343产 地：中国大陆
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T16267Naminidil化合物 T16267BMS 234303-01
Naminidil is an opener of cyanoguanidine KATP.
价 格：￥电议型 号：T16267产 地：中国大陆
