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T15143DMP-543;化合物DMP-543XR-543;XR-543
DMP-543 (XR-543) is a potassium channel (KV7 channel) blocker that enhances the release of neurotransmitters.
价 格:¥电议型 号:T15143产 地:中国大陆
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T15107DFMTI;化合物 T15107MK5435;MK5435
DFMTI can completely block the rmGlu1 L757V glutamate response.
价 格:¥电议型 号:T15107产 地:中国大陆
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T15043D5D-IN-326化合物 T15043D-5D-IN-326|||D5D IN 326|||D5DIN326
D5D-IN-326 is an orally active delta-5 desaturase (D5D) inhibitor (IC50s: 72 and 22 nM for rat and human D5D in enzymic and cell-based assays). It has no effect on D6D or D9D activity. D5D-IN-326 reduces insulin resistance and decreases body weight in diet-induced obese C57BL/6J mice.
价 格:¥电议型 号:T15043产 地:中国大陆
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T15042D2343;化合物 T15042D2343
D2343 is an agonist of β2-adrenoceptor. It also is an inhibitor of α1- adrenoceptor.
价 格:¥电议型 号:T15042产 地:中国大陆
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T14995Concanamycin A;刀豆素AX 4357B|||Antibiotic X 4357B|||Concanamycin;X 4357B|||刀豆素A|||Antibiotic X 4357B||
Concanamycin A is a macrolide antibiotic. It also is a specific inhibitor of vacuolar-type H+-ATPase (V-ATPase).
价 格:¥电议型 号:T14995产 地:中国大陆
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T14968Cinanserin hydrochloride;化合物Cinanserin hydrochlorideSQ 10643;SQ 10643
Cinanserin hydrochloride (SQ 10643) is a high affinity antagonist of the 5-HT2 receptor (Ki: 41 nM) and a 3C-like protease inhibitor of severe acute respiratory syndrome coronavirus.
价 格:¥电议型 号:T14968产 地:中国大陆
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T14963CI-943;化合物 T14963(±)-CI-943;(±)-CI-943
CI-943 is a novel potential antipsychotic drug that does not bind to dopamine (DA) receptors and has some developmental neurotoxicity.
价 格:¥电议型 号:T14963产 地:中国大陆
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T14944CGS 15943;化合物CGS 15943CGS 15943
CGS 15943 is an orally bioavailable non-xanthine antagonist of Adenosine Receptor. In transfected CHO cells, its Ki for human A1, A2A, A2B, and A3 Adenosine Receptors are 3.5, 4.2, 16, and 50 nM , respectively.
价 格:¥电议型 号:T14944产 地:中国大陆
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T14943CGP60474;化合物CGP60474CGP60474
CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC. CGP60474 is also a highly potent anti-endotoxemic agent and inhibits cyclin-dependent kinase (CDK) potently.
价 格:¥电议型 号:T14943产 地:中国大陆
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T14883Idoxifene;化合物 T14883CB7432;CB7432
Idoxifene is a tissue-specific selective estrogen receptor modulator.
价 格:¥电议型 号:T14883产 地:中国大陆
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T1485Methotrexate;甲氨蝶呤NCI-C04671|||WR19039|||Amethopterin|||CL14377;NCI-C04671|||WR19039|||Amethopterin||
Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR. Methotrexate has antimetabolic, antitumor, and immunosuppressive activities, and is commonly used in rheumatoid arthritis and various tumors.
价 格:¥电议型 号:T1485产 地:中国大陆
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T14844BX430;化合物BX430BX430
BX430 is used for chronic pain and cardiovascular disease and it is a potent and selective noncompetitive allosteric human P2X4 receptor channels antagonist with an IC50 of 0.54 μM. BX430 has species specificity.
价 格:¥电议型 号:T14844产 地:中国大陆
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T14843Bifluranol;化合物BifluranolBX341;BX341
Bifluranol (BX341) has anti-androgenic activity and has shown significant anti-prostatic activity in in vivo studies for the treatment of benign prostatic hyperplasia (BPH).
价 格:¥电议型 号:T14843产 地:中国大陆
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T14743Boc-NH-PEG3-sulfonic acid;化合物 T14743Boc-NH-PEG3-sulfonic acid
Boc-NH-PEG3-sulfonic acid is a polyethylene glycol (PEG) derived linker used for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T14743产 地:中国大陆
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T14690BMS 433796;化合物BMS 433796BMS-289948|||BMS-299897;BMS-289948|||BMS-299897
BMS 433796 is a γ-secretase inhibitor that demonstrates Aβ-lowering activity within a transgenic mouse model of Alzheimer´s disease.
价 格:¥电议型 号:T14690产 地:中国大陆
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T14665LMotixafortide TFA(664334-36-5,Free);化合物Motixafortide TFATF 14016 TFA|||BKT140 TFA|||BL-8040 TFA|||T1
Motixafortide TFA(664334-36-5,Free) (BKT140 TFA) is an antagonist of CXCR4 with IC50 of ~1 nM. It induces the apoptosis of AML blasts by down-regulating ERK, BCL-2, MCL-1 and cyclin-D1 via altered miR-15a/16-1 expression.
价 格:¥电议型 号:T14665L产 地:中国大陆
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T14643Bis-PEG5-NHS ester;化合物 T14643Bis-PEG5-NHS ester
Bis-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T14643产 地:中国大陆
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T14559BI 224436;化合物 T14559BI 224436
BI 224436 is an inhibitor of HIV-1 noncatalytic site integrase. With EC50 values of less than 15 nM against different HIV-1 laboratory strains.
价 格:¥电议型 号:T14559产 地:中国大陆
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T14543Benzyloxy carbonyl-PEG3-C2-Boc;化合物 T14543Benzyloxy carbonyl-PEG3-C2-Boc
Benzyloxy carbonyl-PEG3-C2-Boc, an alkyl/ether-based PROTAC linker, is a synthetic compound employed for the synthesis of PROTACs[1].
价 格:¥电议型 号:T14543产 地:中国大陆
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T14511BAY1082439化合物BAY1082439N-[8-[[(2R)-2-羟基-3-(吗啉-4-基)丙基]氧基]-7-甲氧基-2,3-二氢咪唑并[1,2-C]喹唑啉-5-基]-2-甲基吡啶-3-甲酰胺
BAY1082439, an orally bioavailable, selective inhibitor of PI3Kα/β/δ, demonstrates high efficacy in inhibiting the growth of Pten-null prostate cancer [1][2]. Additionally, BAY1082439 is effective against mutated forms of PIK3CA.
价 格:¥电议型 号:T14511产 地:中国大陆