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T16243N-(PEG2-Boc)-N-bis(PEG2-propargyl)；化合物 T16243N-(PEG2-Boc)-N-bis(PEG2-propargyl)
N-(PEG2-Boc)-N-bis(PEG2-propargyl) is a polyethylene glycol (PEG)-based PROTAC linker employed for the synthesis of PROTACs[1].
价 格：￥电议型 号：T16243产 地：中国大陆
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T1615Irbesartan；厄贝沙坦SR-47436|||BMS-186295；厄贝沙坦|||SR-47436|||BMS-186295
Irbesartan (SR-47436) is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.
价 格：￥电议型 号：T1615产 地：中国大陆
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T16144MRX-2843；化合物MRX-2843UNC2371；UNC2371
MRX-2843 (UNC2371) is a potent and orally active inhibitor of MERTK and FLT3(IC50s of 1.3 nM and 0.64 nM, respectively).
价 格：￥电议型 号：T16144产 地：中国大陆
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T16143MRTX-1257；化合物MRTX-1257MRTX-1257
MRTX-1257 is a selective, irreversible, and covalent inhibitor of KRAS G12C. It has an IC50 of 900 pM for KRAS dependent ERK phosphorylation in H358 cells. MRTX1257 demonstrated 31% bioavailability in the mouse, with free fraction exposures well above the cellular potency In a PK/PD experiment, 77% target engagement.
价 格：￥电议型 号：T16143产 地：中国大陆
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T1610Metaxalone；美他沙酮Skelaxin|||Methaxalonum|||Zorane|||NSC170959|||AHR438；Skelaxin|||Methaxalonum|||美他沙酮|
Metaxalone (Methaxalonum) (marketed by King Pharmaceuticals under the brand name Skelaxin ) is a muscle relaxant used to relax muscles and relieve pain caused by strains, sprains, and other musculoskeletal conditions.
价 格：￥电议型 号：T1610产 地：中国大陆
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T16084MK-0343化合物 T16084MRK-409
MK0343 is an orally bioavailable GABAA receptor subtype-selective partial agonist and is a non-sedating anxiolytic.
价 格：￥电议型 号：T16084产 地：中国大陆
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T16082Mivotilate；化合物 T16082YH439；YH439
Mivotilate, a potent, non-toxic aryl hydrocarbon receptor (AhR) activator, functions as a hepatoprotective agent.
价 格：￥电议型 号：T16082产 地：中国大陆
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T16068MF-438；化合物MF-438MF-438
MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1).
价 格：￥电议型 号：T16068产 地：中国大陆
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T16043Metaproterenol；化合物 T16043Orciprenaline；Orciprenaline
Metaproterenol also has anti-inflammatory activity. Metaproterenol is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist (IC50: 68 nM).
价 格：￥电议型 号：T16043产 地：中国大陆
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T1597LProadifen；化合物 T1597LAV-54315|||AV 54315|||AV54315；AV-54315|||AV 54315|||AV54315
Proadifen is a non-selective cytochrome P450 enzymes inhibitor, preventing some types of drug metabolism.
价 格：￥电议型 号：T1597L产 地：中国大陆
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T15947MAC13243 HCl；化合物MAC13243 HClMAC13243 HCl
MAC13243 HCl, an inhibitor of LolA, a periplasmic chaperone that transports lipoproteins from the inner membrane to the outer membrane, is an antimicrobial agent with specificity and significant inhibitory effects on Gram-negative bacteria.
价 格：￥电议型 号：T15947产 地：中国大陆
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T15943M443；化合物 M443M443
M443 is a potent small molecule inhibitor of MRK that inhibits radiation-induced activation of p38 and Chk2 and can be used in cancer research.
价 格：￥电议型 号：T15943产 地：中国大陆
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T15843m-PEG2-Amino；化合物 T15843m-PEG2-Amino
m-PEG2-Amino is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T15843产 地：中国大陆
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T15776Loviride化合物 T15776R 89439
Loviride is a non-nucleoside reverse transcriptase inhibitor (IC50: 0.3 μM). Loviride inhibits HIV-1, HIV-2 and SIV replication in MT-4 cells. It is used for reverse transcriptase from HIV-1.
价 格：￥电议型 号：T15776产 地：中国大陆
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T15743Levomepromazine；化合物 T15743Methotrimeprazine；Methotrimeprazine
Methotrimeprazine is an orally available neuroleptic agent. It is commonly used to relieve nausea and vomiting in palliative care settings. Levomepromazine has antagonist actions at multiple neurotransmitter receptor sites, including cholinergic, dopaminergic, serotonin, and histamine receptors.
价 格：￥电议型 号：T15743产 地：中国大陆
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T15643Kainic acid红藻氨酸红藻氨酸
In the CNS, Kainic acid is an effective agonist at excitatory amino acid receptor subtypes.
价 格：￥电议型 号：T15643产 地：中国大陆
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T15635JZP-430；化合物JZP-430JZP-430
JZP-430 is an effective, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50: 44 nM). It also shows ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL).
价 格：￥电议型 号：T15635产 地：中国大陆
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T15623JNJ-61432059；化合物JNJ-61432059JNJ-61432059
JNJ-61432059 is an oral active and selective negative modulator of TARP γ?8 Selective AMPAR(pIC50: 9.7).
价 格：￥电议型 号：T15623产 地：中国大陆
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T15568Imirestat；咪瑞司他Alcon 1576|||AL 1576|||HOE 843；Alcon 1576|||AL 1576|||咪瑞司他|||HOE 843
Imirestat (HOE 843) is an aldose reductase inhibitor that can be used in diabetes research.
价 格：￥电议型 号：T15568产 地：中国大陆
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T15545ICA-27243；化合物ICA-27243ICA-27243
ICA-27243 is less effective at activating KCNQ4 and KCNQ3/Q5. ICA-27243 is a potent and orally active KCNQ2/Q3 potassium channel opener (EC50: 0.38 μM). ICA-27243 also has antiepileptic and anticonvulsant effects.
价 格：￥电议型 号：T15545产 地：中国大陆
