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T18056K-Ras ligand-Linker Conjugate 3;化合物 T18056K-Ras ligand-Linker Conjugate 3
K-Ras ligand-Linker Conjugate 3 (Compound 001371) is a chemical compound that consists of a ligand for K-Ras recruiting moiety and a PROTAC linker, responsible for recruiting E3 ligases (e.g., VHL, CRBN, MDM2, and IAP). This compound is essential in the synthesis of PROTAC K-Ras Degrader-1, a potent PROTAC K-Ras degrader that demonstrates a degradation efficacy of ≥70% in SW1573 cells[1].
价 格:¥电议型 号:T18056产 地:中国大陆
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T17956Fmoc-N-bis-PEG3-NH-Boc;化合物 T17956Fmoc-N-bis-PEG3-NH-Boc
Fmoc-N-bis-PEG3-NH-Boc is a cleavable ADC linker compound consisting of three PEG units, employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T17956产 地:中国大陆
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T17908VHL Ligand-Linker Conjugates 15;化合物 T17908E3 Ligase Ligand-Linker Conjugates 56;E3 Ligase Ligand-Lin
VHL Ligand-Linker Conjugates 15 is a chemical compound that combines a VHL ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. It is specifically designed for the creation of PROTACs[1].
价 格:¥电议型 号:T17908产 地:中国大陆
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T17856DSPE-PEG36-DBCO;化合物 T17856DSPE-PEG36-DBCO
DSPE-PEG36-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17856产 地:中国大陆
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T17756DBCO-NH-PEG7-C2-NHS ester;化合物 T17756DBCO-NH-PEG7-C2-NHS ester
DBCO-NH-PEG7-C2-NHS ester is a polyethylene glycol (PEG) derived linker that possesses a terminal DBCO moiety. It functions as an N-hydroxysuccinimide (NHS) ester, making it suitable for the efficient synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T17756产 地:中国大陆
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T17656Boc-NH-PEG-amine (MW 2000);化合物 T17656Boc-NH-PEG-amine (MW 2000)
Boc-NH-PEG-amine (MW 2000) is a polyethylene glycol (PEG)-based linker for PROTAC synthesis[1].
价 格:¥电议型 号:T17656产 地:中国大陆
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T1756LIlaprazole;艾普拉唑IY81149|||IY 81149|||IY-81149;IY81149|||艾普拉唑|||IY 81149|||IY-81149
Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. Studies also showed that Ilaprazole significantly prevented the development of reflux oesophagitis.
价 格:¥电议型 号:T1756L产 地:中国大陆
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T17569Biotin-PEG23-azide;化合物 T17569Biotin-PEG23-azide
Biotin-PEG23-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17569产 地:中国大陆
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T17568Biotin-PEG23-amine;化合物 T17568Biotin-PEG23-amine
Biotin-PEG23-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17568产 地:中国大陆
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T17567Biotin-PEG2-OH生物素二聚乙二醇羟基生物素二聚乙二醇羟基
Biotin-PEG2-OH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
价 格:¥电议型 号:T17567产 地:中国大陆
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T17566Biotin-PEG2-CH2CH2N3;化合物Biotin-PEG2-CH2CH2N3Biotin-PEG2-CH2CH2N3
Biotin-PEG2-CH2CH2N3 is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
价 格:¥电议型 号:T17566产 地:中国大陆
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T17565Biotin-PEG2-C2-iodoacetamide;生物素-二聚乙二醇-碘乙酰胺Biotin-PEG2-iodoacetamide;Biotin-PEG2-iodoacetamide|||生物素
Biotin-PEG2-C2-iodoacetamide (Biotin-PEG2-iodoacetamide) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
价 格:¥电议型 号:T17565产 地:中国大陆
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T17564Biotin-PEG2-C1-aldehyde;化合物 T17564Biotin-PEG2-C1-aldehyde
Biotin-PEG2-C1-aldehyde is a polyethylene glycol (PEG)-based linker utilized in synthesizing proteolysis targeting chimeras (PROTACs) [1].
价 格:¥电议型 号:T17564产 地:中国大陆
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T17563Biotin-PEG2-aldehyde;化合物 T17563Biotin-PEG2-aldehyde
Biotin-PEG2-aldehyde is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17563产 地:中国大陆
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T17562Biotin-PEG12-TFP ester;化合物 T17562Biotin-PEG12-TFP ester
Biotin-PEG12-TFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17562产 地:中国大陆
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T17561Biotin-PEG12-NHS ester生物素十二聚乙二醇琥珀酰亚胺酯生物素十二聚乙二醇琥珀酰亚胺酯
Biotin-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
价 格:¥电议型 号:T17561产 地:中国大陆
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T17560Biotin-PEG12-Mal;化合物 T17560Biotin-PEG12-Mal
Biotin-PEG12-Mal is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17560产 地:中国大陆
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T1756Ilaprazole sodium;艾普拉唑钠IY-81149 sodium;IY-81149 sodium|||艾普拉唑钠
Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor. A weak base, Ilaprazole accumulates in the acidic environment of the secretory canaliculus of the gastric parietal cell where it is converted to an active sulfenamide form that binds to cysteine sulfhydryl groups on the luminal aspect of the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting the pump´s activity and the par
价 格:¥电议型 号:T1756产 地:中国大陆
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T17556Biotin-PEG11-azide;化合物 T17556Biotin-PEG11-azide
Biotin-PEG11-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17556产 地:中国大陆
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T17456Azide-PEG-alcohol (MW 2000);化合物 T17456Azide-PEG-alcohol (MW 2000)
Azide-PEG-alcohol, a polyethylene glycol (PEG)-based PROTAC linker with a molecular weight of 2000, functions as a versatile option for the synthesis of PROTACs[1].
价 格:¥电议型 号:T17456产 地:中国大陆