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T1736Apixaban阿哌沙班阿哌沙班|||BMS-562247-01
Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the conversion of prothrombin to thrombin and preventing the formation of cross-linked fibrin clots.
价 格：￥电议型 号：T1736产 地：中国大陆
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T17356Acid-propionylamino-Val-Cit-OH；化合物 T17356Acid-propionylamino-Val-Cit-OH
Acid-propionylamino-Val-Cit-OH is a cleavable linker commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T17356产 地：中国大陆
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T17256Wnt pathway activator 1；化合物Wnt pathway activator 1Wnt pathway activator 1
Wnt pathway activator 1 is a potent Wnt activator with an IC50 of 28-29 nM. Wnt pathway activator 1 is a potent Wnt activator for the treatment of androgenetic alopecia (AGA).
价 格：￥电议型 号：T17256产 地：中国大陆
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T17201UK 356618化合物 T17201UK 356618
UK 356618 is a potent and selective inhibitor of matrix metalloprotease-3 (IC50: 5.9 nM).
价 格：￥电议型 号：T17201产 地：中国大陆
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T17183TY-52156；化合物TY-52156TY-52156
TY-52156 is an effective and selective S1P3 receptor antagonist (Ki: 110 nM).
价 格：￥电议型 号：T17183产 地：中国大陆
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T17175Troxacitabine；化合物 T17175BCH-4556|||SGX-145|||SGX145|||SPD-758|||BCH4556|||beta-L-OddC；BCH-4556|||SGX
Troxacitabine, a DNA polymerase inhibitor, is potentially used for the treatment of acute myeloid leukemia (AML). In comparison with gemcitabine, troxacitabine was equally active against MiaPaCa and was more efficacious against Panc-01.
价 格：￥电议型 号：T17175产 地：中国大陆
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T17171Trofinetide；化合物TrofinetideNNZ-2566；NNZ-2566
Trofinetide (NNZ-2566) is a synthetic analog of the endogenous N-terminus tripeptide. It has been shown to be neuroprotective in animal models of brain injury.
价 格：￥电议型 号：T17171产 地：中国大陆
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T17156Tradipitant；化合物TradipitantVLY-686|||LY686017；VLY-686|||LY686017
Tradipitant (VLY-686) is an antagonist of neurokinin-1.
价 格：￥电议型 号：T17156产 地：中国大陆
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T17095TIK-301；化合物 T17095PD-6735|||LY-156735；PD-6735|||LY-156735
TIK-301 is a chlorinated melatonin derivative and a potent, high-affinity, and orally active melatonin MT1 and MT2 receptors agonist (Kis: 0.081 nM and 0.042 nM, respectively). TIK-301 is also a 5-HT2B/5-HT2C receptor antagonist with antidepressant action. TIK-301 has the potential for sleep disorders and other circadian rhythm disorders treatment.
价 格：￥电议型 号：T17095产 地：中国大陆
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T17056Tetrahydrobiopterin；四氢生物蝶呤Sapropterin|||BH4|||(Rac)-Sapropterin；Sapropterin|||BH4|||(Rac)-Sapropteri
Tetrahydrobiopterin (BH4) is a cofactor for aromatic amino acid hydroxylases and an essential cofactor for nitric oxide synthase (NOS), which is used in the study of endothelial dysfunction such as hypertension, hypercholesterolemia, and diabetes.
价 格：￥电议型 号：T17056产 地：中国大陆
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T17047Tetrabenazine-d6丁苯那嗪 D6Ro 1-9569 D6|||丁苯那嗪 D6
Tetrabenazine D6 is the deuterium-labeled Tetrabenazine. Tetrabenazine is a VMAT-inhibitor used for the treatment of hyperkinetic movement disorder.
价 格：￥电议型 号：T17047产 地：中国大陆
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T16995TAS05567；化合物 T16995TAS05567
TAS05567 is a potent, highly selective, and ATP-competitive Syk inhibitor (IC50: 0.37 nM). TAS05567 only shows >70% inhibition of Syk and 4 other kinases (FLT3, JAK2, KDR, and RET with IC50s of 10 nM, 4.8 nM, 600 nM, and 29 nM, respectively) in a panel of 192 kinases.
价 格：￥电议型 号：T16995产 地：中国大陆
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T16986Tanomastat；化合物 T16986BAY 12-9566；BAY 12-9566
Tanomastat is an orally bioavailable and non-peptidic biphenyl matrix metalloproteinases inhibitor. For MMP-2, MMP-3, MMP-9, MMP-13 the Ki values are 11, 143, 301, and 1470 nM respectively.
价 格：￥电议型 号：T16986产 地：中国大陆
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T16956Sulfo DBCO-amine；化合物 T16956Sulfo DBCO-amine
Sulfo DBCO-amine is an alkyl chain-derived PROTAC linker utilized for synthesizing PROTACs[1].
价 格：￥电议型 号：T16956产 地：中国大陆
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T16864SCH 563705；化合物 T16864SCH 563705
SCH 563705 is an effective and orally available CXCR2 and CXCR1 antagonist (IC50s: 1.3 nM, 7.3 nM and Kis of 1 and 3 nM, respectively).
价 格：￥电议型 号：T16864产 地：中国大陆
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T16856SB228357；化合物SB228357SB228357
SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively.
价 格：￥电议型 号：T16856产 地：中国大陆
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T16852SB-568849；化合物 T16852SB-568849
SB-568849 is a melanin-concentrating hormone receptor 1 antagonist (pKi: 7.7).
价 格：￥电议型 号：T16852产 地：中国大陆
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T16850SB-265610；化合物SB-265610GSK-CXCR2；GSK-CXCR2
SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis (IC50s: 3.7 nM and 70 nM, respectively).
价 格：￥电议型 号：T16850产 地：中国大陆
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T16845Sarolaner；化合物SarolanerPF-6450567；PF-6450567
Sarolaner (PF-6450567) is an orally active and broad-spectrum ectoparasiticide (LC80: 0.3 μg/mL against C. felis and an LC100: 0.003 μg/mL against O. turicata).
价 格：￥电议型 号：T16845产 地：中国大陆
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T16791Rottlerin；粗糠柴苦素Mallotoxin|||NSC 56346|||NSC 94525；Mallotoxin|||NSC 56346|||粗糠柴苦素|||NSC 94525
Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM). Rottlerin causes apoptosis via caspase 3 activation.
价 格：￥电议型 号：T16791产 地：中国大陆
