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T5150Treprostinil；曲前列尼尔LRX-15|||Orenitram|||Remodulin；LRX-15|||曲前列环素|||Orenitram|||曲前列尼尔|||Remodulin
Treprostinil (Orenitram) is a potent DP1, IP and EP2 agonist (EC50: 0.6/1.9/6.2 nM).
价 格：￥电议型 号：T5150产 地：中国大陆
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T4258TLR7 agonist 2；化合物TLR7-agonist-1TLR7-agonist-1|||TLR7-IN-1；TLR7-agonist-1|||TLR7-IN-1
TLR7 agonist 2 (TLR7-IN-1) is a specific and effective Toll-like Receptor 7 (TLR7) agonist (LEC=0.4 μM).
价 格：￥电议型 号：T4258产 地：中国大陆
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T4231MD2-IN-1；化合物MD2-IN-1inhibit|||MD2-IN-1|||Inhibitor|||MD2IN1|||Toll-like Receptor (TLR)|||MD-2-IN-1||
MD2-IN-1 is a Myeloid differentiation protein 2 (MD2) inhibitor with a KD of 189 ?μM for the recombinant human MD2 (rhMD2).
价 格：￥电议型 号：T4231产 地：中国大陆
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T41173FAM-DEALAHypYIPMDDDFQLRSF；FAM-DEALAHypYIPMDDDFQLRSFFAM-DEALAHypYIPMDDDFQLRSF
FAM-DEALAHypYIPMDDDFQLRSF is a 5,6-carboxyfluorescein (FAM) labeled HIF-1α peptide. It binds with high affinity to von Hippel-Lindau (VHL) protein (KD= 3 nM). Can be used to assess ligand binding to VHL in a direct fluorescence polarization (FP) displacement assay. Excitation/emission maxima (λ) = 485/520 nm. This product is a longer peptide version of FAM-DEALA-Hyp-YIPD.
价 格：￥电议型 号：T41173产 地：中国大陆
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T403684-Ethylresorcinol；4-乙基间苯二酚4-Ethylresorcinol
4-Ethylresorcinol, a derivative of resorcinol, functions as a tyrosinase substrate, possesses hypopigmentary effects, attenuates mRNA and protein expression of tyrosinase-related protein-2 (TRP-2), and exhibits antioxidative properties through inhibition of lipid peroxidation.
价 格：￥电议型 号：T40368产 地：中国大陆
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T40040TLR8 agonist 2 hydrochloride；TLR8 agonist 2 hydrochlorideTLR8 agonist 2 hydrochloride
TLR8 agonist 2 hydrochloride is a highly potent and selective agonist for human TLR8, exhibiting an EC50 of 3 nM. However, its activity towards human TLR7 is considerably weaker, with an EC50 of 33.33 μM.
价 格：￥电议型 号：T40040产 地：中国大陆
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T40039TLR8 agonist 2TLR8 agonist 2TLR8 agonist 2
TLR8 agonist 2 is a highly effective and specific compound that activates TLR8, possessing an EC 50 of 3 nM in human TLR8. Notably, TLR8 agonist 2 demonstrates lower activity towards human TLR7, with an EC 50 of 33.33 μM.
价 格：￥电议型 号：T40039产 地：中国大陆
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T39970TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride；TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochlorideT
TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) is a drug-linker conjugate used in antibody-drug conjugates (ADCs) with high efficacy against tumors. It consists of TLR7/8 agonist 4, a potent TLR7/8 agonist, linked to the ADC linker hydroxy-PEG10-acid which can be cleaved.
价 格：￥电议型 号：T39970产 地：中国大陆
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T39969TLR7/8 agonist 4 TFA；TLR7/8 agonist 4 TFATLR7/8 agonist 4 TFA
TLR7/8 agonist 4 TFA (compound 41) is a highly potent TLR7/8 agonist that exhibits significant anti-cancer activity.
价 格：￥电议型 号：T39969产 地：中国大陆
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T39968TLR7/8 agonist 4 hydroxy-PEG10-acid；TLR7/8 agonist 4 hydroxy-PEG10-acidTLR7/8 agonist 4 hydroxy-PEG1
TLR7/8 agonist 4 hydroxy-PEG10-acid (compound 9) is a drug-linker conjugate employed in antibody-drug conjugates (ADC). This compound exhibits remarkable antitumor activity by utilizing TLR7/8 agonist 4, which acts as a potent activator of TLR7/8. The TLR7/8 agonist 4 is linked to hydroxy-PEG10-acid, the ADC linker, via a cleavable bond. Overall, it demonstrates promising pharmaceutical potential in the context of ADC-based therapeutics.
价 格：￥电议型 号：T39968产 地：中国大陆
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T39669TLR7/8/9-IN-1；TLR7/8/9-IN-1TLR7/8/9-IN-1；TLR7/8/9-IN-1
TLR7/8/9-IN-1 is a potent inhibitor of Toll-like receptors 7/8/9 (TLR7/8/9) with an IC50 of 43 nM.
价 格：￥电议型 号：T39669产 地：中国大陆
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T39607NLRP3 modulators 1NLRP3 modulators 1NLRP3 modulators 1
NLRP3 modulators 1 (WO2017184746A1, compound 107) is a potent modulator of NLRP3, capable of agonizing or partially agonizing the activity of NLRP3. This compound proves valuable in investigating conditions, diseases, or disorders where a reduction in LRP3 activity plays a role in the pathology.
价 格：￥电议型 号：T39607产 地：中国大陆
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T39552NLRP3-IN-5NLRP3-IN-5NLRP3-IN-5
NLRP3-IN-5, a compound disclosed in WO2016131098, is an inhibitor of NLRP3 inflammasome. It consists of the chemical structure N-((4-chloro-2,6-dimethylphenyl)carbamoyl)-4-(2-hydroxypropan-2-l)furan-2-sulfonamide.
价 格：￥电议型 号：T39552产 地：中国大陆
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T39258PulrodemstatPulrodemstatLSD1-IN-7|||CC-90011
Pulrodemstat (CC-90011) is a highly potent and selective inhibitor of lysine specific demethylase-1 (LSD1). It exhibits a reversible mode of action and can be administered orally. With an impressive IC50 of 0.25 nM, Pulrodemstat effectively suppresses the enzymatic activity of LSD1. Notably, it demonstrates minimal inhibition against LSD2, MOA-A, and MAO-B enzymes. Moreover, Pulrodemstat possesses remarkable anticancer properties, promoting differentiation in acute myeloid leukemia (AML) and sma
价 格：￥电议型 号：T39258产 地：中国大陆
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T38614TLR7 agonist 3；TLR7 agonist 3TLR7 agonist 3
TLR7 agonist 3 (Compound 2), a potent activator of toll-like receptor 7 (TLR7), plays a critical role in initiating immune responses, positioning it as a promising target for immunomodulator development.
价 格：￥电议型 号：T38614产 地：中国大陆
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T38563Raptinal；化合物RaptinalRaptinal
Raptinal activates caspase-3 directly and initiates intrinsic caspase-dependent apoptosis pathway in multiple cell lines.
价 格：￥电议型 号：T38563产 地：中国大陆
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T38547TLR4-IN-C34-C2-COOH；TLR4-IN-C34-C2-COOHTLR4-IN-C34-C2-COOH；TLR4-IN-C34-C2-COOH
TLR4-IN-C34-C2-COO is a linker compound that incorporates TLR4 inhibitor TLR4-IN-C34. It effectively inhibits TLR4 activity in enterocytes and macrophages. Moreover, it demonstrates a notable ability to mitigate systemic inflammation in murine models of endotoxemia and necrotizing enterocolitis.
价 格：￥电议型 号：T38547产 地：中国大陆
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T3843Pinosylvin；银松素3,5-stilbenediol|||5-Styrylresorcinol；银松素|||3,5-stilbenediol|||5-Styrylresorcinol
Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.
价 格：￥电议型 号：T3843产 地：中国大陆
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T3820Iridin；野鸢尾苷Lridin；野鸢尾苷|||Lridin
Iridin (Lridin) is major active ingredient of Iris dichotoma which could be used as the drug for pain, inflammation treatment
价 格：￥电议型 号：T3820产 地：中国大陆
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T38078TLR7/8-IN-1；化合物TLR7/8-IN-1TLR7/8-IN-1；TLR7/8-IN-1
TLR7/8-IN-1, a crystalline TLR7/TLR8 inhibitor, is a valuable compound for autoimmune disease research[1].
价 格：￥电议型 号：T38078产 地：中国大陆
