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T18678SC-VC-PAB-DM1;化合物 T18678SC-VC-PAB-DM1
SC-VC-PAB-DM1 is a drug-linker conjugate utilized in Antibody-Drug Conjugates (ADC), featuring DM1 (Mertansine, a tubulin inhibitor) linked through the SC-VC-PAB[1] ADC linker to deliver potent antitumor activity.
价 格:¥电议型 号:T18678产 地:中国大陆
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T18677SC-Val-Cit-PAB;化合物 T18677SC-Val-Cit-PAB
SC-Val-Cit-PAB is a cleavable ADC linker for antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T18677产 地:中国大陆
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T18656S-acetyl-PEG2-Boc化合物S-acetyl-PEG2-BocTert-Butyl 3-[2-(2-Acetylsulfanylethoxy)Ethoxy]Propanoate|||S-A
S-acetyl-PEG2-Boc (S-Acetyl-PEG2-T-Butyl Ester) is a PEG-based PROTAC linker. S-acetyl-PEG2-Boc can be used in the synthesis of PROTACs.
价 格:¥电议型 号:T18656产 地:中国大陆
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T18653S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate;化合物 T18653s-1-hydroxy-2-methylpropan-2-yl-me
S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate, an ADC linker, is a glutathione cleavable compound used for the attachment of monoclonal antibodies (mAb) in antibody-drug conjugates (ADCs). It specifically refers to the Alkyl-Chain composition of the linker portion of these molecules [1].
价 格:¥电议型 号:T18653产 地:中国大陆
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T18647Pyrene-PEG5-propargyl;化合物 T18647Pyrene-PEG5-propargyl
Pyrene-PEG5-propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18647产 地:中国大陆
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T18641SirReal1-O-propargyl;化合物 T18641PROTAC Sirt2-binding moiety 1;PROTAC Sirt2-binding moiety 1
SirReal1-O-propargyl, a moiety based on SirReal1, is a selective and highly potent inhibitor of Sirtuin 2 (Sirt2), demonstrating an IC50 of 2.4 μM. It operates by binding to the cereblon ligand through a linker, facilitating the formation of PROTAC for the degradation of Sirt2[1].
价 格:¥电议型 号:T18641产 地:中国大陆
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T18622BnOH-NH-bis-(C2-S)-propane-O-isoprene ester;化合物 T18622PROTAC Linker 29;PROTAC Linker 29
BnOH-NH-bis-(C2-S)-propane-O-isoprene ester (PROTAC Linker 29) is an alkyl ether-based linker primarily utilized in the synthesis of PROTACs.
价 格:¥电议型 号:T18622产 地:中国大陆
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T1861Omipalisib;化合物OmipalisibGSK458|||GSK2126458;GSK458|||GSK2126458
Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.
价 格:¥电议型 号:T1861产 地:中国大陆
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T18603PROTAC BRD4 degrader for PAC-1;化合物 T18603PROTAC BRD4 degrader for PAC-1
PROTAC BRD4 degrader for PAC-1 (compound 5) is a chimeric BET degrader GNE-987 conjugated with a disulfide-containing linker[1]. This PROTAC-linker conjugate specifically targets and degrades BRD4, enabling selective proteolysis of PAC-1.
价 格:¥电议型 号:T18603产 地:中国大陆
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T18594HG-7-85-01-Decyclopropane;化合物 T18594PROTAC ABL binding moiety 3;PROTAC ABL binding moiety 3
Decyclopropane, also known as HG-7-85-01, is a chemical compound with ABL inhibitor properties. It binds to the IAP ligand through a linker, resulting in the formation of SNIPER [1].
价 格:¥电议型 号:T18594产 地:中国大陆
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T18591Propargyl-PEG8-SH;化合物 T18591Propargyl-PEG8-SH
Propargyl-PEG8-SH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18591产 地:中国大陆
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T18590Propargyl-PEG7-methane;化合物 T18590Propargyl-PEG7-methane
Propargyl-PEG7-methane is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18590产 地:中国大陆
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T18589Propargyl-PEG6-SH;化合物 T18589Propargyl-PEG6-SH
Propargyl-PEG6-SH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18589产 地:中国大陆
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T18588Propargyl-PEG5-Ms;化合物Propargyl-PEG5-MsPropargyl-PEG6-Ms;Propargyl-PEG6-Ms
Propargyl-PEG5-Ms (Propargyl-PEG6-Ms) is a PEG-based PROTAC linker. Propargyl-PEG5-Ms can be used in the synthesis of PROTACs.
价 格:¥电议型 号:T18588产 地:中国大陆
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T18587Propargyl-PEG4-Sulfone-PEG4-Boc;化合物 T18587Propargyl-PEG4-Sulfone-PEG4-Boc
Propargyl-PEG4-Sulfone-PEG4-Boc is a polyethylene glycol (PEG)-based linker molecule for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T18587产 地:中国大陆
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T18586Propargyl-PEG4-Sulfone-PEG4-acid;化合物 T18586Propargyl-PEG4-Sulfone-PEG4-acid
Propargyl-PEG4-Sulfone-PEG4-acid serves as a PEG-based PROTAC linker for the synthesis of PROTACs[1].
价 格:¥电议型 号:T18586产 地:中国大陆
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T18585Propargyl-PEG4-S-PEG4-propargyl;化合物 T18585Propargyl-PEG4-S-PEG4-propargyl
Propargyl-PEG4-S-PEG4-propargyl is a PEG-based PROTAC linker employed for PROTAC synthesis [1].
价 格:¥电议型 号:T18585产 地:中国大陆
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T18584Propargyl-PEG4-S-PEG4-Boc;化合物 T18584Propargyl-PEG4-S-PEG4-Boc
Propargyl-PEG4-S-PEG4-Boc is a polyethylene glycol (PEG) based linker, specifically designed for the synthesis of PROTACs [1].
价 格:¥电议型 号:T18584产 地:中国大陆
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T18583Propargyl-PEG4-S-PEG4-acid;化合物 T18583Propargyl-PEG4-S-PEG4-acid
Propargyl-PEG4-S-PEG4-acid is a polyethylene glycol (PEG)-based PROTAC linker, suitable for the synthesis of Proteolysis Targeting Chimera (PROTACs)[1].
价 格:¥电议型 号:T18583产 地:中国大陆
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T18582Propargyl-PEG4-hydrazide;化合物 T18582Propargyl-PEG4-hydrazide
Propargyl-PEG4-hydrazide is a non-cleavable 4-unit polyethylene glycol (PEG) linker specifically designed for antibody-drug conjugate (ADC) synthesis [1].
价 格:¥电议型 号:T18582产 地:中国大陆