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T18331MC-VC-PABC-DNA31;化合物 T18331MC-VC-PABC-DNA31
MC-VC-PABC-DNA31 is a drug-linker conjugate designed for Antibody-Drug Conjugates (ADC) that demonstrates potent antitumor activity. It employs DNA31, an effective inhibitor of RNA polymerase, connected through the MC-VC-PABC ADC linker.
价 格:¥电议型 号:T18331产 地:中国大陆
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T18330MC-Val-Cit-PAB-vinblastine;化合物 T18330MC-Val-Cit-PAB-vinblastine
MC-Val-Cit-PAB-vinblastine is a potent antitumor drug-linker conjugate for Antibody-Drug Conjugates (ADC), featuring vinblastine (a microtubule protein inhibitor) connected through the MC-Val-Cit-PAB ADC linker.
价 格:¥电议型 号:T18330产 地:中国大陆
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T18329MC-VC(S)-PABQ-Tubulysin M;化合物 T18329MC-Val-Cit-PAB-tubulysin5a;MC-Val-Cit-PAB-tubulysin5a
MC-Val-Cit-PAB-tubulysin5a is a drug-linker conjugate for ADC with potent antitumor activity by using tubulysin5a (a tubulin inhibitor), linked via the ADC linker MC-Val-Cit-PAB.
价 格:¥电议型 号:T18329产 地:中国大陆
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T18328MC-Val-Cit-PAB-rifabutin;化合物 T18328MC-Val-Cit-PAB-rifabutin
MC-Val-Cit-PAB-rifabutin is a drug-linker conjugate designed for antibody-drug conjugates (ADC), featuring the potent antitumor agent rifabutin (a DNA-dependent RNA polymerase inhibitor) connected through the MC-Val-Cit-PAB ADC linker. This configuration endows it with significant antitumor activity.
价 格:¥电议型 号:T18328产 地:中国大陆
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T18327MC-Val-Cit-PAB-Retapamulin;化合物 T18327MC-Val-Cit-PAB-Retapamulin
MC-Val-Cit-PAB-Retapamulin is a drug-linker conjugate for antibody-drug conjugates (ADC) that exhibits potent antitumor activity. This compound utilizes Retapamulin, a ribosome inhibitor, connected through the ADC linker MC-Val-Cit-PAB.
价 格:¥电议型 号:T18327产 地:中国大陆
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T18326MC-Val-Cit-PAB-MMAF;化合物 T18326MC-Val-Cit-PAB-MMAF
MC-Val-Cit-PAB-MMAF is an antibody-drug conjugate (ADC) component that exhibits antitumor properties through the action of the tubulin inhibitor, monomethyl auristatin F (MMAF), which is connected by a cathepsin-cleavable linker, MC-Val-Cit-PAB.
价 格:¥电议型 号:T18326产 地:中国大陆
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T18324MC-Val-Cit-PAB-duocarmycin chloride;化合物 T18324MC-Val-Cit-PAB-duocarmycin;MC-Val-Cit-PAB-duocarmycin
MC-Val-Cit-PAB-duocarmycin is an antibody-drug conjugate (ADC) linker that combines duocarmycin, a potent DNA minor groove-binding alkylating agent, with an antitumor drug through the MC-Val-Cit-PAB linker, exhibiting significant antitumor activity.
价 格:¥电议型 号:T18324产 地:中国大陆
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T18323MC-Val-Cit-PAB-dimethylDNA31;化合物 T18323MC-Val-Cit-PAB-dimethylDNA31
MC-Val-Cit-PAB-dimethylDNA31 is a drug-linker conjugate employed in antibody-drug conjugates (ADCs) that exhibits robust antitumor efficacy. This conjugate utilizes the ADC linker, MC-Val-Cit-PAB, to link to the potent antitumor agent dimethylDNA31. Notably, dimethylDNA31 also demonstrates significant bactericidal activity against both persister and stationary-phase Staphylococcus aureus.
价 格:¥电议型 号:T18323产 地:中国大陆
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T18322MC-Val-Cit-PAB-clindamycin;化合物 T18322MC-Val-Cit-PAB-clindamycin
MC-Val-Cit-PAB-clindamycin is an antibody-drug conjugate (ADC) linker that combines the potent antitumor properties of clindamycin, a protein synthesis inhibitor, with the ADC linker MC-Val-Cit-PAB, to enhance its ability to target and kill cancer cells effectively.
价 格:¥电议型 号:T18322产 地:中国大陆
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T18321Mc-Val-Cit-PAB-Cl;化合物Mc-Val-Cit-PAB-ClMc-Val-Cit-PAB-Cl
Mc-Val-Cit-PAB-Cl, a cleavable ADC linker, is utilized in the conjugation of MMAE and antibodies to produce compounds such as antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE), which demonstrate cytotoxicity with IC50s of 3.3 and 0.95 nM against BJAB and WSU cell lines, respectively.
价 格:¥电议型 号:T18321产 地:中国大陆
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T18320MC-Val-Cit-PAB-carfilzomib iodide;化合物 T18320MC-Val-Cit-PAB-carfilzomib;MC-Val-Cit-PAB-carfilzomib
MC-Val-Cit-PAB-carfilzomib is a potent antitumor drug-linker conjugate for antibody-drug conjugates (ADC), comprising the irreversible proteasome inhibitor carfilzomib, connected through the ADC linker MC-Val-Cit-PAB.
价 格:¥电议型 号:T18320产 地:中国大陆
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T18319MC-Val-Cit-PAB-Auristatin E;化合物 T18319MC-Val-Cit-PAB-Auristatin E
MC-Val-Cit-PAB-Auristatin E is an antibody-drug conjugate (ADC) linker compound featuring Auristatin E, a potent cytotoxic tubulin modifier, connected through the MC-Val-Cit-PAB linker, exhibiting significant antitumor activity.
价 格:¥电议型 号:T18319产 地:中国大陆
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T18318MC-Val-Ala-PAB-PNP;化合物MC-Val-Ala-PAB-PNPinhibit|||ADC Linkers|||Inhibitor|||MC Val Ala PAB PNP|||Ant
MC-Val-Ala-PAB-PNP is a cleavable ADC linker. MC-Val-Ala-PAB-PNP can be used in the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T18318产 地:中国大陆
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T18316MC-Sq-Cit-PAB-Gefitinib;化合物 T18316MC-Sq-Cit-PAB-Gefitinib
MC-Sq-Cit-PAB-Gefitinib is a potent antitumor drug-linker conjugate for Antibody-Drug Conjugates (ADC), utilizing Gefitinib—an EGFR tyrosine kinase inhibitor—connected through the MC-Sq-Cit-PAB ADC linker.
价 格:¥电议型 号:T18316产 地:中国大陆
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T18315MC-Sq-Cit-PAB-Dolastatin10;化合物 T18315MC-Sq-Cit-PAB-Dolastatin10
MC-Sq-Cit-PAB-Dolastatin10 is a potent antitumor drug-linker conjugate for Antibody-Drug Conjugates (ADC), utilizing Dolastatin10 (a tubulin polymerization inhibitor) connected through the MC-Sq-Cit-PAB ADC linker.
价 格:¥电议型 号:T18315产 地:中国大陆
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T18305Mal-VC-PAB-DM1;化合物 T18305Mal-VC-PAB-DM1
Mal-VC-PAB-DM1, a drug-linker conjugate for antibody-drug conjugates (ADCs), exhibits potent antitumor activity. It incorporates DM1, a potent microtubule-disrupting agent, connected through the ADC linker Mal-VC-PAB [1].
价 格:¥电议型 号:T18305产 地:中国大陆
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T18304Mal-VC-PAB-ABAEP-Azonafide;化合物 T18304Mal-VC-PAB-ABAEP-Azonafide|||MalVCPABABAEPAzonafide|||Mal VC PA
Mal-VC-PAB-ABAEP-Azonafide, an ADC (antibody-drug conjugate) linker-drug conjugate, demonstrates potent antitumor activity. It incorporates Azonafide, a cytotoxin, connected through the ADC linker Mal-VC-PAB[1].
价 格:¥电议型 号:T18304产 地:中国大陆
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T18303Mal-Phe-C4-VC-PAB-MMAE;化合物 T18303Mal-Phe-C-4-VC-PAB-MMAE|||Mal Phe C4 VC PAB MMAE|||Mal-Phe-C4-VC-PA
Mal-Phe-C4-VC-PAB-MMAE is a chemical compound resulting from the conjugation of monomethyl auristatin E (MMAE), a potent tubulin inhibitor serving as a toxin payload in antibody-drug conjugates, with a Mal-Phe-C4-VC-PAB linker.
价 格:¥电议型 号:T18303产 地:中国大陆
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T18302Mal-Phe-C4-VC-PAB-DMEA-PNU-159682;化合物 T18302Mal Phe C4 VC PAB DMEA PNU 159682|||Mal-Phe-C4-VC-PAB-DM
Mal-Phe-C4-VC-PAB-DMEA-PNU-159682 is a drug-linker conjugate utilized in antibody-drug conjugate (ADC) therapy. It comprises the ADC linker Mal-Phe-C4-VC-PAB and the potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 encompasses metabolites of nemorubicin (MMDX) derived from liver microsomes, as well as the ADC cytotoxin PNU-159682[1].
价 格:¥电议型 号:T18302产 地:中国大陆
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T18301Mal-Phe-C4-Val-Cit-PAB;化合物 T18301Mal-Phe-C4-Val-Cit-PAB
Mal-Phe-C4-Val-Cit-PAB is a cleavable antibody-drug conjugate (ADC) linker featuring a Maleimide functional group. It is employed in the synthesis of ADCs.
价 格:¥电议型 号:T18301产 地:中国大陆