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T18561Propargyl-C2-NHS ester;化合物 T18561Propargyl-C2-NHS ester
Propargyl-C2-NHS ester is a nonclaevable linker for antibody-drug-conjugation (ADC).
价 格:¥电议型 号:T18561产 地:中国大陆
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T18560Propargyl-C1-NHS ester;4-戊炔酸琥珀亚胺酯4-Pentynoic Acid Succinimidyl Ester;4-戊炔酸琥珀亚胺酯|||4-Pentynoic Acid S
Propargyl-C1-NHS ester (4-Pentynoic Acid Succinimidyl Ester) is a nonclaevable linker used for antibody-drug-conjugation (ADC).
价 格:¥电议型 号:T18560产 地:中国大陆
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T18540Phe-Lys(Trt)-PAB;化合物Phe-Lys(Trt)-PABPhe-Lys(Trt)-PAB
Phe-Lys(Trt)-PAB is a cathepsin-cleavable linker utilized in the development of antibody-drug conjugates (ADCs)[1], serving as a crucial component for facilitating the release of therapeutic agents within targeted cells.
价 格:¥电议型 号:T18540产 地:中国大陆
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T18539Phe-Lys(Fmoc)-PAB;化合物 T18539Phe-Lys(Fmoc)-PAB
Phe-Lys(Fmoc)-PAB is a cathepsin cleavable ADC linker employed in the conjugation of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T18539产 地:中国大陆
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T18515Palbociclib-propargyl;化合物 T18515PROTAC CDK6 ligand 1;PROTAC CDK6 ligand 1
Palbociclib-propargyl, a PROTAC ligand targeting the protein CDK6, connects to the CRBN ligand through a PEG linker to form PROTAC CP-10. CP-10 exhibits a potent DC50 value of 2.1 nM against CDK6[1].
价 格:¥电议型 号:T18515产 地:中国大陆
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T18514PAC;化合物 T18514PAC
PAC is a chemical conjugate consisting of an ADCs linker and PROTACs linked to an antibody. When PAC is conjugated to an antibody, it exhibits enhanced degradation of estrogen receptor-alpha (ERα) in comparison to PROTAC alone.
价 格:¥电议型 号:T18514产 地:中国大陆
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T18512OPSS-Val-Cit-PAB-PNP;化合物 T18512OPSS Val Cit PAB PNP|||OPSS-Val-Cit-PAB-PNP|||OPSSValCitPABPNP;OPSS V
OPSS-Val-Cit-PAB-PNP is a cleavable linker employed in ADC (antibody-drug conjugates) synthesis [1].
价 格:¥电议型 号:T18512产 地:中国大陆
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T18511OPSS-Val-Cit-PAB-OH;化合物 T18511OPSS-Val-Cit-PAB-OH
OPSS-Val-Cit-PAB-OH is an ADC linker utilized for the synthesis of antibody-drug conjugates (ADCs) [1].
价 格:¥电议型 号:T18511产 地:中国大陆
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T18488NH2-MPAA-NODA;化合物 T18488NH2MPAANODA|||NH2-MPAA-NODA|||NH-2-MPAA-NODA|||NH2 MPAA NODA;NH2MPAANODA|||N
NH2-MPAA-NODA, a nitroveratryl-based photocleavable linker featuring a NODA motif and a methyl phenyl acetic acid (MPAA) backbone, serves as a radiolabel when labeled with 18F-fluoride.
价 格:¥电议型 号:T18488产 地:中国大陆
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T18475N3-PEG6-Propanehydrazide;化合物 T18475N3-PEG6-Propanehydrazide
N3-PEG6-Propanehydrazide is a polyethylene glycol (PEG) derived linker, specifically designed for use in the synthesis of proteolysis targeting chimeras (PROTACs) [1].
价 格:¥电议型 号:T18475产 地:中国大陆
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T18473N3-PEG3-vc-PAB-MMAE;化合物 T18473N3PEG3vcPABMMAE|||N3-PEG3-vc-PAB-MMAE|||N-3-PEG3-vc-PAB-MMAE|||N3 PEG3
N3-PEG3-vc-PAB-MMAE, a drug-linker conjugate designed for Antibody-Drug Conjugates (ADC), features the integration of monomethyl auristatin E (MMAE), a tubulin inhibitor, via a 3-unit polyethylene glycol (PEG) linker. This compound demonstrates significant antitumor activity.
价 格:¥电议型 号:T18473产 地:中国大陆
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T18472N3-PEG3-Propanehydrazide;化合物 T18472N3-PEG3-Propanehydrazide
N3-PEG3-Propanehydrazide serves as a PEG-based PROTAC linker, employed for PROTAC synthesis [1].
价 格:¥电议型 号:T18472产 地:中国大陆
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T18462N-(Propanoic acid)-N-bis(m-PEG12);化合物 T18462N-(Propanoic acid)-N-bis(m-PEG12)
N-(Propanoic acid)-N-bis(m-PEG12) is a polyethylene glycol (PEG) based linker for PROTACs synthesis[1].
价 格:¥电议型 号:T18462产 地:中国大陆
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T18451N-methyl-N’-methyl-O-(m-PEG4)-O’-(propargyl-PEG4)-Cy5;化合物 T18451n-methyl-n-methyl-o-m-peg4-o-proparg
N-methyl-N´-methyl-O-(m-PEG4)-O´-(propargyl-PEG4)-Cy5 is a polyethylene glycol (PEG)-based linker commonly employed in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T18451产 地:中国大陆
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T18450N-methyl-N’-methyl-O-(m-PEG4)-O’-(propargyl-PEG4)-Cy3;化合物 T18450n-methyl-n-methyl-o-m-peg4-o-proparg
N-methyl-N´-methyl-O-(m-PEG4)-O´-(propargyl-PEG4)-Cy3 is a polyethylene glycol (PEG)-based linker used for the synthesis of proteolysis targeting chimeras (PROTACs) [1].
价 格:¥电议型 号:T18450产 地:中国大陆
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T18432N-(m-PEG4)-N’-(m-PEG4)-O-(m-PEG4)-O’-(propargyl-PEG4)-Cy5;化合物 T18432n-m-peg4-n-m-peg4-o-m-peg4-o-pro
N-(m-PEG4)-N´-(m-PEG4)-O-(m-PEG4)-O´-(propargyl-PEG4)-Cy5 serves as a PEG-based PROTAC linker, facilitating the synthesis of PROTACs[1].
价 格:¥电议型 号:T18432产 地:中国大陆
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T1838Sapanisertib;沙帕色替TAK-228|||MLN0128|||INK 128;沙帕色替|||TAK-228|||MLN0128|||INK 128
Sapanisertib (INK 128) is an orally bioavailable inhibitor of raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2) with potential antineoplastic activity.
价 格:¥电议型 号:T1838产 地:中国大陆
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T18364Tesirine;化合物 T18364MP-PEG8-VA-PABC-PBD Dimer|||Tesirine|||Tesirine|||MP-PEG8-VA-PABC-PBD Dimer|||MP-
MP-PEG8-VA-PABC-PBD Dimer is a drug-linker conjugates for ADC which is used in the treatment of several cancers. PBD Dimer is a DNA alkylating which inhibits DNA replication[1].
价 格:¥电议型 号:T18364产 地:中国大陆
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T18333mDPR(Boc)-Val-Cit-PAB;化合物 T18333mDPR(Boc)-Val-Cit-PAB
mDPR(Boc)-Val-Cit-PAB is a cleavable linker employed in antibody-drug conjugates (ADCs) [1]. This chemical compound serves as a reliable linker in the formation of ADCs, which are biopharmaceuticals that combine the specificity of monoclonal antibodies with the potency of cytotoxic drugs for targeted cancer therapy [1].
价 格:¥电议型 号:T18333产 地:中国大陆
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T18332MC-VC-PABC-Aur0101;化合物 T18332MCVCPABCAur0101|||MC-VC-PABC-Aur-0101|||MC VC PABC Aur0101|||MC-VC-PABC
MC-VC-PABC-Aur0101 is a potent anticancer drug-linker conjugate designed for Antibody-Drug Conjugates (ADCs), comprising Aur0101, an auristatin microtubule inhibitor, connected through the MC-VC-PABC linker to enhance antitumor efficacy.
价 格:¥电议型 号:T18332产 地:中国大陆