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T18300Mal-Phe-C4-Val-Cit-PAB-DMEA;化合物 T18300Mal-Phe-C4-Val-Cit-PAB-DMEA|||Mal-Phe-C-4-Val-Cit-PAB-DMEA|||M
The chemical compound Mal-Phe-C4-Val-Cit-PAB-DMEA is a cleavable antibody-drug conjugate (ADC) linker that incorporates a Maleimide group. It is commonly employed in the synthesis of ADCs.
价 格:¥电议型 号:T18300产 地:中国大陆
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T18299Mal-PEG8-Val-Cit-PAB-MMAE;化合物 T18299MalPEG8ValCitPABMMAE|||Mal PEG8 Val Cit PAB MMAE|||Mal-PEG-8-Val
Mal-PEG8-Val-Cit-PAB-MMAE is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T18299产 地:中国大陆
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T18294Mal-PEG4-VC-PAB-DMEA;化合物 T18294Mal-PEG4-VC-PAB-DMEA|||MalPEG4VCPABDMEA|||Mal PEG4 VC PAB DMEA|||Mal-
Mal-PEG4-VC-PAB-DMEA is a cleavable ADC linker that incorporates a Maleimide moiety. It is employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T18294产 地:中国大陆
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T18293Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA;化合物 T18293Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA
Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA is an antibody-drug conjugate linker that incorporates the antitumor antibiotic Duocarmycin SA, connected through the Mal-PEG4-VC-PAB-DMEA-Seco linker, for targeted cancer therapy.
价 格:¥电议型 号:T18293产 地:中国大陆
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T18292Mal-PEG4-VC-PAB-DMEA-PNU-159682;化合物 T18292Mal-PEG4-VC-PAB-DMEA-PNU159682|||MalPEG4VCPABDMEAPNU159682
Mal-PEG4-VC-PAB-DMEA-PNU-159682 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) therapy. It combines the ADC linker, Mal-PEG4-VC-PAB, with the potent ADC cytotoxin, DMEA-PNU-159682. The cytotoxin, DMEA-PNU-159682, is derived from metabolites of nemorubicin (MMDX) found in liver microsomes, as well as the ADC cytotoxin PNU-159682[1].
价 格:¥电议型 号:T18292产 地:中国大陆
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T18291Mal-PEG4-Val-Cit-PAB;化合物 T18291Mal-PEG4-Val-Cit-PAB
Mal-PEG4-Val-Cit-PAB, a cleavable ADC linker incorporating a Maleimide moiety, finds application in the construction of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T18291产 地:中国大陆
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T18288Mal-?PEG4-?propargyl;化合物 T18288Mal-?PEG4-?propargyl
Mal- PEG4- propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
价 格:¥电议型 号:T18288产 地:中国大陆
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T1827Buparlisib;布帕尼西BKM120|||NVP-BKM120;BKM120|||布帕尼西|||NVP-BKM120
Buparlisib (BKM120) is an orally bioavailable specific oral inhibitor of the pan-class I PI3K (IC50s: 52/166/116/nM for p110α, p110β, and p110δ).
价 格:¥电议型 号:T1827产 地:中国大陆
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T18268Mal-PEG1-Val-Cit-PABC-OH;化合物 T18268Mal-PEG1-Val-Cit-PABC-OH
Mal-PEG1-Val-Cit-PABC-OH is a 1 unit polyethylene glycol (PEG) ADC linker that possesses cleavable properties. This linker, commonly utilized in the synthesis of antibody-drug conjugates (ADCs), serves as a critical component facilitating the conjugation of drugs to antibodies[1].
价 格:¥电议型 号:T18268产 地:中国大陆
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T18252Mal-L-PA-NH-Boc;化合物 T18252mDPR(boc);mDPR(boc)
Mal-L-PA-NH-Boc, a noncleavable ADC linker, facilitates the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T18252产 地:中国大陆
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T18251MAL-di-EG-Val-Cit-PAB-MMAF;化合物 T18251MAL-di-EG-Val-Cit-PAB-MMAF
MAL-di-EG-Val-Cit-PAB-MMAF refers to a chemical compound that comprises the linker (MAL-di-EG-Val-Cit-PAB) and the potent blocker of tubulin polymerization (MMAF, Monomethyl auristatin F)[1].
价 格:¥电议型 号:T18251产 地:中国大陆
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T18250MAL-di-EG-Val-Cit-PAB-MMAE;化合物 T18250MAL di EG Val Cit PAB MMAE|||MALdiEGValCitPABMMAE|||MAL-di-EG-V
MAL-di-EG-Val-Cit-PAB-MMAE comprises the linker MAL-di-EG-Val-Cit-PAB and the potent tubulin inhibitor MMAE, which are essential components of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T18250产 地:中国大陆
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T18240Mal-amido-PEG2-Val-Cit-PAB-OH;化合物 T18240Mal-amido-PEG2-Val-Cit-PAB-OH
Mal-amido-PEG2-Val-Cit-PAB-OH is a bi-functional polyethylene glycol (PEG) linker, comprised of two PEG units, that can be cleaved. It is specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T18240产 地:中国大陆
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T18221m-PEG8-ethoxycarbonyl-propanoic acid;化合物 T18221m-PEG8-ethoxycarbonyl-propanoic acid
m-PEG8-ethoxycarbonyl-propanoic acid, a PEG-derived PROTAC linker, is employed for the synthesis of PROTACs[1].
价 格:¥电议型 号:T18221产 地:中国大陆
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T18199m-PEG37-Propargyl;化合物 T18199m-PEG37-Propargyl
m-PEG37-Propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18199产 地:中国大陆
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T18189m-PEG3-Sulfone-PEG4-propargyl;化合物 T18189m-PEG3-Sulfone-PEG4-propargyl
m-PEG3-Sulfone-PEG4-propargyl is a polyethylene glycol (PEG)-based prodrug-induced degradation (PROTAC) linker. It is utilized in the efficient synthesis of PROTACs, a class of heterobifunctional molecules designed to selectively target and degrade specific protein targets[1].
价 格:¥电议型 号:T18189产 地:中国大陆
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T18183m-PEG3-S-PEG4-propargyl;化合物 T18183m-PEG3-S-PEG4-propargyl
m-PEG3-S-PEG4-propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18183产 地:中国大陆
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T18176m-PEG25-Propargyl;化合物 T18176m-PEG25-Propargyl
m-PEG25-Propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18176产 地:中国大陆
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T18136m-PEG12-COO-propanoic acid;化合物 T181363-(m-PEG12-ethoxycarbonyl)propanoic acid;3-(m-PEG12-ethoxycarbo
m-PEG12-COO-propanoic acid is a polyethylene glycol (PEG) derivative utilized as a PROTAC linker for synthesizing PROTAC compounds [1].
价 格:¥电议型 号:T18136产 地:中国大陆
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T18070Lenalidomide-propargyl-C2-NH2 hydrochloride;化合物 T18070Lenalidomide-propargyl-C2-NH2 hydrochloride
Lenalidomide-propargyl-C2-NH2 hydrochloride is a compound that features a cereblon (CRBN) ligand for the E3 ubiquitin ligase, as well as a linker. It is utilized in the development of the PROTAC MD-224[1] system.
价 格:¥电议型 号:T18070产 地:中国大陆