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  • T23128PD180970PD-180970,PD180970

    PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit. PD180970 can be used in studies about chronic myelogenous leukemia.

    价 格：￥电议型 号：T23128产 地：中国大陆

  • T9522RimtuzalcapKcsA,movement,small-conductance,channels,Rimtuzalcap,SK channels,CAD1883,CAD 1883,tremor,

    Rimtuzalcap (CAD-1883) is a first-in-class selective positive allosteric modulator of small-conductance calcium-activated potassium channels (SK channels). Rimtuzalcap can be used for the research of movement disorders including spinocerebellar ataxia (SCA) and essential tremor (ET).

    价 格：￥电议型 号：T9522产 地：中国大陆

  • T10945D18024D18024,D-18024

    D18024 is a phthalazinonderivat with anti-allergic and anti-histamine effect.

    价 格：￥电议型 号：T10945产 地：中国大陆

  • T6171BI-D1870

    BI-D1870 is a cell-permeable, ATP-competitive inhibitor of ribosomal S6 kinases (RSKs; IC50s: 31/24/18/15 nM for RSK1/2/3/4).

    价 格：￥电议型 号：T6171产 地：中国大陆

  • T274518α-Glycyrrhetinic acid18-α-甘草次酸；甘草次酸；Enoxolone；Glycyrrhetinic acid

    Enoxolone (INN, BAN; also known as glycyrrhetinic acid) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb licorice. It is used in flavoring and it masks the

    价 格：￥电议型 号：T2745产 地：中国大陆

  • T21635PD184161

    PD184161 is a novel, orally-active MEK inhibitor. PD184161 inhibited MEK activity (IC50 = 10-100 nM) in a time- and concentration-dependent manner[1].

    价 格：￥电议型 号：T21635产 地：中国大陆

  • T14589Biotin-PEG3-acid18-[(3AS,4S,6AR)-六氢-2-氧代-1H-噻吩并[3,4-D]咪唑-4-基]-14-氧代-4,7,10-三氧杂-13-氮杂十八烷酸

    Biotin-PEG3-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs.Biotin-PEG3-acid is a heterobiofunctional biotin PEG derivative containing a carboxylic acid group. The hydrophilic PEG spacer arm imparts water sol

    价 格：￥电议型 号：T14589产 地：中国大陆

  • T1181GefitinibZD1839；吉非替尼

    Gefitinib is an EGFR tyrosine kinase inhibitor and can inhibit Tyr1173, Tyr992, Tyr1173 and Tyr992 (IC50s: 37/37/26/57 nM).

    价 格：￥电议型 号：T1181产 地：中国大陆

  • T1181GefitinibGefitinib,ZD1839,

    Gefitinib is an EGFR tyrosine kinase inhibitor and can inhibit Tyr1173, Tyr992, Tyr1173 and Tyr992 (IC50s: 37/37/26/57 nM).

    价 格：￥电议型 号：T1181产 地：美洲

  • T6171BI-D1870BI-D1870

    BI-D1870 is a cell-permeable, ATP-competitive inhibitor of ribosomal S6 kinases (RSKs; IC50s: 31/24/18/15 nM for RSK1/2/3/4).

    价 格：￥电议型 号：T6171产 地：美洲

  • T83880C18 Ceramide-1-phosphate (d18:1/18:0) ammonium；化合物 C18 Ceramide-1-phosphate (d18:1/18:0) ammoniumCer

    C18 Ceramide-1-phosphate (d18:1/18:0) is a long-chain molecule identified in murine skin known to promote the migration of mouse bone marrow-derived multipotent stromal cells and human umbilical vein endothelial cells (HUVECs) at concentrations of 0.5 to 5 ?M. It exhibits elevated levels in CFPAC-1 pancreatic ductal adenocarcinoma cells compared to pancreatic cancer stem cells, and its myocardial concentration is heightened in Langendorff isolated perfused mouse hearts under an ex vivo ischemia

    价 格：￥电议型 号：T83880产 地：中国大陆

  • T78915AD186；化合物 AD186AD186

    AD186, a potent and selective S1R agonist, exhibits dissociation constants (Kis) of 2.7 nM for S1R and 27 nM for S2R. Notably, AD186 completely reverses the antiallodynic effect of BD-1063 [1].

    价 格：￥电议型 号：T78915产 地：中国大陆

  • T67974Berberine ursodeoxycholate；小檗碱熊去氧胆酸盐HTD1801|||BUDCA；HTD1801|||BUDCA

    Berberine ursodeoxycholate (HTD1801) is an orally effective hypolipidemic agent, an ionic salt of Berberine and Ursodeoxycholic acid.Berberine ursodeoxycholate has a wide range of metabolic activity and significantly reduces liver fat content. Berberine ursodeoxycholate has been used in studies of hyperlipidemia, non-alcoholic steatohepatitis (NASH) and diabetes.

    价 格：￥电议型 号：T67974产 地：中国大陆

  • T6171BI-D1870；化合物BI-D1870BI-D1870

    BI-D1870 is a cell-permeable, ATP-competitive inhibitor of ribosomal S6 kinases (RSKs; IC50s: 31/24/18/15 nM for RSK1/2/3/4).

    价 格：￥电议型 号：T6171产 地：中国大陆

  • T61390D18；化合物 D18D18

    D18 is an immune modulator that acts as a dual agonist for TLR7/8 (with EC50 values of 24 nM for hTLR7 and 10 nM for hTLR8, respectively). It enhances the expression of PD-L1 through epigenetic regulation, thereby increasing the sensitivity of tumors to PD-1/PD-L1 blockade. Additionally, D18 functions as a cytotoxin for ADC synthesis, specifically for the ADC HE-S2 [1].

    价 格：￥电议型 号：T61390产 地：中国大陆

  • T40452N-Acetylpsychosine；N-AcetylpsychosineN-Acetylpsychosine|||C2 Galactosylceramide (d18:1/2:0)；N-Acetyl

    N-Acetylpsychosine, also known as α-galactosylated C2-ceramide (d18:1/2:0), exhibits immunostimulatory properties. This compound, N-Acetylpsychosine, holds potential as a valuable tool for studying the mechanisms of apoptosis and immune responses activated by dendritic cells (DCs).

    价 格：￥电议型 号：T40452产 地：中国大陆

  • T38452L-threo Lysosphingomyelin (d18:1)；L-threo Lysosphingomyelin (d18:1)L-threo-Sphingosylphosphorylcholi

    L-threo Lysosphingomyelin (d18:1) (L-threo-Sphingosylphosphorylcholine) is a naturally occurring bioactive sphingolipid. It acts as a potent agonist for S1P receptors, with EC50 values of 19.3, 131.8, and 313.3 nM for hS1P1, hS1P3, and hS1P2, respectively.

    价 格：￥电议型 号：T38452产 地：中国大陆

  • T38354Lactosylsphingosine (d18:1)；Lactosylsphingosine (d18:1)Lactosylsphingosine (d18:1)；Lactosylsphingosi

    Lactosylsphingosine is a bioactive sphingolipid and a form of lactosylceramide that is lacking the fatty acyl group. Lyso-lactosylceramide (1-50 μM) reduces viability of human neutrophils in a concentration-dependent manner. Unlike lactosylceramide,lactosylsphingosine has no effect on protein synthesis and cell proliferation in cardiomyocytes. Lactosylsphingosine is a precursor in the synthesis of lyso-ganglioside GM3.

    价 格：￥电议型 号：T38354产 地：中国大陆

  • T38286C26 Sphingomyelin (d18:1/26:0)；C26 Sphingomyelin (d18:1/26:0)C26 Sphingomyelin (d18:1/26:0)；C26 Sphi

    C26 Sphingomyelin is a sphingolipid that has been found in serum and cell or brain extracts.1,2,3C26 sphingomyelin levels are increased in the serum of patients with hemophagocytic lymphohistiocytosis, an inflammatory condition characterized by excessive immune activation.3C26 sphingomyelin has been used a component of monolayers to study the influence of sphingomyelin acyl chain length on sphingomyelin-sterol interactions.4[Matreya, LLC.]

    价 格：￥电议型 号：T38286产 地：中国大陆

  • T38282C22 Glucosylceramide (d18:1/22:0)；C22 Glucosylceramide (d18:1/22:0)C22 Glucosylceramide (d18:1/22:0)

    C22 Glucosylceramide (d18:1/22:0) is an endogenous glucosylceramide. Glucosylceramides are major constituents of skin lipid membranes where they play a role in maintaining the water permeability barrier. They are precursors in the synthesis of lactosylceramide , as well as oligoglycolipids and gangliosides. Phospholipase A2 (PLA2) type XIIA knockdown increases C22 glucosylceramide (d18:1/22:0) expression in rat brain. It is also increased in the brain, but not the liver or spinal cord, of mice f

    价 格：￥电议型 号：T38282产 地：中国大陆

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