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T38281C22 Galactosylceramide (d18:1/22:0)；C22 Galactosylceramide (d18:1/22:0)C22 Galactosylceramide (d18:1
C22 Galactosylceramide is a sphingolipid that has been found in the central nervous system.1,2C22 Galactosylceramide levels are increased in the spinal cord, but not the brain or liver, of mice fed a methionine-restricted diet.1C22 Galactosylceramide has been found in postmortem hippocampus from patients with Alzheimer´s disease.2[Matreya, LLC.]
价 格：￥电议型 号：T38281产 地：中国大陆
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T382131-β-D-Glucosylsphingadienine (d18:2 (4E,8E))；1-β-D-Glucosylsphingadienine (d18:2 (4E,8E))1-β-D-Gluco
1-β-D-Glucosylsphingadienine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucosylcerebrosides . They are formed when sphingosines undergo glucosidation by UDP-glucose. Glucosylsphingosines completely reduce neurite outgrowth and induce death of LA-N-2 cells at concentrations of 10 and 50 μM, respectively. They also decrease the activity of glucocerebrosidase in LA-N-2 cells in a dose-dependent manner. Glucosylsphingosine levels are elevated in patients with Gaucher&
价 格：￥电议型 号：T38213产 地：中国大陆
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T38182C17 Sphingomyelin (d18:1/17:0)；C17 Sphingomyelin (d18:1/17:0)C17 Sphingomyelin (d18:1/17:0)；C17 Sphi
C17 Sphingomyelin is a synthetic derivative of sphingomyelin that has been used as an internal standard for the quantification of sphingomyelin.
价 格：￥电议型 号：T38182产 地：中国大陆
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T38181C17 Lactosylceramide (d18:1/17:0)；C17 Lactosylceramide (d18:1/17:0)C17 Lactosylceramide (d18:1/17:0)
C17 Lactosylceramide is a naturally occurring sphingolipid that has been found in human brain metastases of lung adenocarcinomas but not in healthy brain tissue.
价 格：￥电议型 号：T38181产 地：中国大陆
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T38011C2 Adamantanyl Globotriaosylceramide (d18:1/2:0)；C2 Adamantanyl Globotriaosylceramide (d18:1/2:0)C2
C2 Adamantanyl globotriaosylceramide (AdaGb3) is a bioactive sphingolipid and water-soluble form of globotriaosylceramide that contains an adamantanyl group in place of the fatty acyl chain. It inhibits Vero toxin binding to globotriaosylceramide in an ELISA assay when used at a concentration of 10 μM. AdaGb3 decreases cell surface expression of P-glycoprotein (P-gp) and reduces efflux of rhodamine 123 in MDCK cells. It also increases apical-to-basal transport of vinblastine in human intestinal
价 格：￥电议型 号：T38011产 地：中国大陆
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T38000Lysosphingomyelin (d18:1)；Lysosphingomyelin (d18:1)Lysosphingomyelin (d18:1)
Sphingomyelins are complex membrane lipids composed of phosphorylcholine, sphingosine, and an acylated group, such as a fatty acid. Lysosphingomyelin is a naturally-occurring lipid which is produced by the removal of the acylated group of sphingomyelin by a deacylase. Lysosphingomyelin may, in turn, serve as a substrate for autotaxin, which removes choline to produce sphingosine-1-phosphate. The receptors and signaling pathways that are activated by lyso-sphingosine are diverse and vary between
价 格：￥电议型 号：T38000产 地：中国大陆
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T3792813C6 Glucosylsphingosine (d18:1)；13C6 Glucosylsphingosine (d18:1)13C6 Glucosylsphingosine (d18:1)
13C6 Glucosylsphingosine (d18:1) is an isotopically enriched form of 1-β-D-glucosylsphingosine (d18:1) that is intended for use as an internal standard for the quantification of 1-β-D-glucosylsphingosine by GC- or LC-MS. 1-β-D-Glucosylsphingosine is a lysolipid derivative of glucosylcerebroside that decreases activity of glucocerebrosidase in LA-N-2 cells in a dose-dependent manner.
价 格：￥电议型 号：T37928产 地：中国大陆
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T37872C16 Galactosylceramide (d18:1/16:0)；C16 Galactosylceramide (d18:1/16:0)C16 Galactosylceramide (d18:1
C16 Galactosylceramide is a glycosphingolipid that contains a galactose moiety attached to a ceramide acylated with palmitic acid .
价 格：￥电议型 号：T37872产 地：中国大陆
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T37565C6 D-threo Ceramide (d18:1/6:0)；C6 D-threo Ceramide (d18:1/6:0)C6 D-threo Ceramide (d18:1/6:0)；C6 D-
C6 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM). It is metabolically inactive and, unlike C6 L-erythro ceramide , C6 D-threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase. C6 D-threo Ceramide promotes survival of isolated rat spinal neurons when used at concentrations up to 2.5 μM but induces cell death at concentrations greater
价 格：￥电议型 号：T37565产 地：中国大陆
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T37564C4 Ceramide (d18:1/4:0)；C4 Ceramide (d18:1/4:0)C4 Ceramide (d18:1/4:0)|||Cer(d18:1/4:0)；C4 Ceramide
C4 Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. [1] [2] [3] It inhibits IL-4 production by 16% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 μM. [1] C4 Ceramide is cytotoxic to SK-BR-3 and MCF-7/Adr breast cancer cells (IC50s = 15.9 and 19.9 μM, respectively). [2] C4 Ceramide also increases maturation and stability of cystic fibrosis transmembrane conductance regulator (CFTR) proteins bearing
价 格：￥电议型 号：T37564产 地：中国大陆
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T37563C22 Ceramide (d18:1/22:0)；C22神经酰胺(d18：1/22：0)Cer(d18:1/22:0)|||C22 Ceramide|||Ceramide (d18:1/22:0)；
C22 Ceramide (d18:1/22:0) (C22 Ceramide), a long-chain ceramide containing behenic acid, is an endogenous bioactive sphingolipid.C22-Ceramide specifically inhibits MCSR and reduces C16 ceramide channel formation in isolated rat liver mitochondria and liposomes.
价 格：￥电议型 号：T37563产 地：中国大陆
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T37562C16 Ceramide；N-棕榈酰神经鞘氨醇N-acylsphingosine|||C16 Ceramide (d18:1/16:0)|||Palmitoyl Ceramide|||N-Palmit
C16 Ceramide (Palmitoyl Ceramide) is a naturally occurring small molecule that activates p53 by directly and selectively binding to it.
价 格：￥电议型 号：T37562产 地：中国大陆
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T37461EOS (d18:1/32:1/18:2)；EOS (d18:1/32:1/18:2)EOS (d18:1/32:1/18:2)
EOS is a ceramide found in the outer layer of the epidermis in mammals. It is comprised of an ω-hydroxy very long-chain ceramide (C28-36) esterified to the essential fatty acid linoleic acid . The consecutive regio- and stereospecific oxygenation of the linoleate portion of EOS by 12(R)-lipoxygenase (12(R)-LO) and eLOX3 is essential for the maintenance of the epidermal barrier to prevent water loss. Following oxygenation, the oxidized linoleate is hydrolyzed, leaving the ω-hydroxy end of the ver
价 格：￥电议型 号：T37461产 地：中国大陆
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T37457C18 L-threo Ceramide (d18:1/18:0)；C18 L-threo Ceramide (d18:1/18:0)C18 L-threo Ceramide (d18:1/18:0)
C18 L-threo Ceramide is a synthetic ceramide and stereoisomer of C18 ceramide that has been used for structural characterization of natural sphingolipids. It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50 value of 0.21 mol% (16.8 μM).
价 格：￥电议型 号：T37457产 地：中国大陆
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T37456C18 L-erythro Ceramide (d18:1/18:0)；C18 L-erythro Ceramide (d18:1/18:0)C18 L-erythro Ceramide (d18:1
C18 L-erythro Ceramide is a naturally occurring ceramide and stereoisomer of C18 ceramide . It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50 value of 0.11 mol% (8.8 μM).
价 格：￥电议型 号：T37456产 地：中国大陆
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T37455C18 D-threo Ceramide (d18:1/18:0)；C18 D-threo Ceramide (d18:1/18:0)C18 D-threo Ceramide (d18:1/18:0)
C18 D-threoCeramide (d18:1/18:0) is a synthetic ceramide and stereoisomer of C18 ceramide .1It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50value of 16.6 μM.2
价 格：￥电议型 号：T37455产 地：中国大陆
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T37454C16 dihydro Ceramide (d18:0/16:0)；C16 dihydro Ceramide (d18:0/16:0)Ceramide (d18:0/16:0)|||Cer(d18:0
C16 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C16 ceramide (d18:0/16:0) that lacks the 4,5-trans double bond.[1] C16 dihydro Ceramide (0-46 nM) inhibits C16 ceramide-induced membrane permeabilization, measured as cytochrome C oxidation, in rat liver mitochondria in a concentration-dependent manner. It also inhibits C16 ceramide-induced channel formation in liposomes. C16 dihydro ceramide is biologically inactive as a single agent, lacking the ability
价 格：￥电议型 号：T37454产 地：中国大陆
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T37440C2 Adamantanyl Galactosylceramide (d18:1/2:0)；C2 Adamantanyl Galactosylceramide (d18:1/2:0)C2 Adaman
C2 Adamantanyl Galactosylceramide (d18:1/2:0) (AdaGalCer) is a bioactive sphingolipid. It reduces globotriaosylceramide 3 synthesis from exogenous lactosylceramide in microsomes. AdaGalCer stimulates recombinant glucocerebrosidase activity in a pH-dependent manner. It activates glucocerebrosidase to decrease glucosylceramide accumulation in fibroblasts and lymphoblasts isolated from patients with Gaucher and Fabry disease, respectively.
价 格：￥电议型 号：T37440产 地：中国大陆
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T37439C18 Globotriaosylceramide (d18:1/18:0)；C18 Globotriaosylceramide (d18:1/18:0)C18 Globotriaosylcerami
C18 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from lactosylceramide . It inhibits aggregation of human neutrophils induced by phorbol 12-myristate 13-acetate (PMA; 10008014) when used at a concentration of 1 μM. C18 globotriaosylceramide acts as a receptor for Shiga toxin in B cell-derived Raji cells and THP-1 monocytes. It accumulates in the brain, heart, kidney, liver, lung, and spleen in a mouse model of Fabry disease, a lysosoma
价 格：￥电议型 号：T37439产 地：中国大陆
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T37438C17 Globotriaosylceramide (d18:1/17:0)；C17 Globotriaosylceramide (d18:1/17:0)C17 Globotriaosylcerami
C17 Globotriaosylceramide is a sphingolipid that has been used as an internal standard for the quantification of globotriaosylceramides in plasma and urine from patients with Fabry disease by GC-MS.
价 格：￥电议型 号：T37438产 地：中国大陆
