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T35808C18:1 Ceramide (d18:1/18:1(9Z));C18:1 Ceramide (d18:1/18:1(9Z))Cer(d18:1/18:1(9Z));Cer(d18:1/18:1(9Z
C18:1 Ceramide is a naturally occurring ceramide.[1][2][3] Levels of C18:1 ceramide are elevated in overweight and insulin-resistant mice and cattle.[1][2] C18:1 Ceramide is also increased in the plasma and ovarian tissue of patients with advanced ovarian cancer. [3]
价 格:¥电议型 号:T35808产 地:中国大陆
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T35807C18 dihydro Ceramide (d18:0/18:0);C18 dihydro Ceramide (d18:0/18:0)C18 dihydro Ceramide (d18:0/18:0)
C18 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C18 ceramide that lacks the 4,5-trans double bond. [1] Increased C18 dihydroceramide lipid levels lead to increased triacylglycerol storage and autophagosome accumulation as well as upregulation of the fibrosis markers α-SMA and FGF2 in Chang and LX-2 liver cells. C18 dihydro Ceramide is elevated in the plasma of pre-diabetics up to 9 years prior to the onset of type 2 diabetes. [2] It is also elevated in
价 格:¥电议型 号:T35807产 地:中国大陆
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T35806N-Stearoylsphingosine;N-硬脂酰神经鞘氨醇C(18:0)/C(18:1)|||Cer(d18:1/18:0)|||C18 Ceramide (d18:1/18:0)|||C18
N-Stearoylsphingosine (Cer(d18:1/18:0)) is an amide compound widely found in eukaryotic organisms that enhances protein phosphatase 2A (PP2A) activity by interfering with the binding of PP2A to PP2A inhibitor 2, leading to dephosphorylation of Akt.N-Stearoylsphingosine is used in prostate cancer research.
价 格:¥电议型 号:T35806产 地:中国大陆
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T35805C16 Sphingomyelin (d18:1/16:0);化合物 C16 Sphingomyelin (d18:1/16:0)Sphingomyelin 16:0|||N-Palmitoyl-D-
C16 Sphingomyelin (d18:1/16:0) (N-Palmitoyl-D-sphingomyelin) is a phospholipid analog of phospholipid bilayer membranes, which can be used to study biofilm activity.
价 格:¥电议型 号:T35805产 地:中国大陆
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T35804C16 Lactosylceramide (d18:1/16:0);C16 Lactosylceramide (d18:1/16:0)C16 Lactosylceramide (d18:1/16:0)
C16 Lactosylceramide is an endogenous bioactive sphingolipid. It forms membrane microdomains with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors (GPCRs), suggesting a role in cell signaling. Plasma levels of C16 lactosylceramide are elevated in insulin-resistant cattle. C16 Lactosylceramide is also upregulated in a mouse model of Niemann-Pick type C1 disease, a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder.
价 格:¥电议型 号:T35804产 地:中国大陆
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T35803C14 Ceramide (d18:1/14:0);十四酰鞘氨醇Cer(d18:1/14:0)|||N-Myristoyl-D-sphingosine;Cer(d18:1/14:0)|||N-Myri
C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson´s research.
价 格:¥电议型 号:T35803产 地:中国大陆
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T29028TZD18;化合物 T29028TZD-18|||TZD 18;TZD-18|||TZD 18
TZD18, a novel PPAR alpha/gamma dual agonist, inhibits cell growth and induces apoptosis in human glioblastoma T98G cells.
价 格:¥电议型 号:T29028产 地:中国大陆
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T26936C188;化合物 T26936Cpd188|||STAT3-IN-C188|||Cpd-188|||C 188|||C-188;Cpd188|||STAT3-IN-C188|||Cpd-188|||C
C188 is a cell-permeable naphthol compound and a STAT3 inhibitor. C188 inhibits IL-6-stimulated STAT3 Tyr705 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket, while exhibiting little effect against IFN-γ-stimulated HepG2 cellular STAT1 phosphorylation.
价 格:¥电议型 号:T26936产 地:中国大陆
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T23128PD180970;化合物PD180970PD 180970;PD 180970
PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit. PD180970 can be used in studies about chronic myelogenous leukemia.
价 格:¥电议型 号:T23128产 地:中国大陆
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T21635PD184161;化合物PD 184161PD184161
PD184161 is a novel, orally-active MEK inhibitor. PD184161 inhibited MEK activity (IC50 = 10-100 nM) in a time- and concentration-dependent manner[1].
价 格:¥电议型 号:T21635产 地:中国大陆
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T21260Psychosine;鞘氨醇半乳糖苷Sphingosine galactoside|||Galactosylsphingosine|||Galactosylsphingosine (d18:1);Sp
Psychosine (Galactosylsphingosine) is a PKC inhibitor, a substrate for the enzyme galactosylceramide cerebrosidase (GALC), and a potential biomarker of Krabbe´s disease.Psychosine is highly cytotoxic and induces cell death in a variety of cells.
价 格:¥电议型 号:T21260产 地:中国大陆
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T14589Biotin-PEG3-acid化合物Biotin-PEG3-acid18-[(3AS,4S,6AR)-六氢-2-氧代-1H-噻吩并[3,4-D]咪唑-4-基]-14-氧代-4,7,10-三氧杂-13
Biotin-PEG3-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs.Biotin-PEG3-acid is a heterobiofunctional biotin PEG derivative containing a carboxylic acid group. The hydrophilic PEG spacer arm imparts water solubility that is transferred to the biotinylated molecule. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
价 格:¥电议型 号:T14589产 地:中国大陆
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T11891Lumefantrine-d18;苯芴醇 D18Benflumetol D18|||Lumefantrine D18;Benflumetol D18|||苯芴醇 D18|||Lumefantrine
Lumefantrine D18 is an antimalarial drug, and is the deuterium labeled Lumefantrine.
价 格:¥电议型 号:T11891产 地:中国大陆
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T1181Gefitinib;吉非替尼ZD1839;ZD1839|||吉非替尼
Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations. Gefitinib has antitumor activity and is used for the treatment of EGFR-mutated non-small-cell lung cancers. Gefitinib administration RESULTS in the development of the EGFR C797S resistance mutation.
价 格:¥电议型 号:T1181产 地:中国大陆
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T11384Gefitinib-d8;化合物 T11384ZD1839 D8|||Gefitinib D8;ZD1839 D8|||Gefitinib D8
Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib D8 is a deuterium labeled Gefitinib.
价 格:¥电议型 号:T11384产 地:中国大陆
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T10945D18024;化合物D18024D18024
D18024 is a phthalazinonderivat with anti-allergic and anti-histamine effect.
价 格:¥电议型 号:T10945产 地:中国大陆
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T003618β-Glycyrrhetinic acid18β-甘草次酸Enoxolone|||甘草次酸|||18β-甘草次酸|||Glycyrrhetin
18β-Glycyrrhetinic acid (Enoxolone) is the major bioactive component of Glycyrrhizae Radix and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties.
价 格:¥电议型 号:T0036产 地:中国大陆