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T11750LKDOAM-25 trihydrochloride (2230731-99-2 free base);化合物 T11750LKDOAM-25 trihydrochloride;KDOAM-25 tri
KDOAM-25 trihydrochloride increases global H3K4 methylation at transcriptional start sites and impairs proliferation in multiple myeloma MM1S cells. KDOAM-25 trihydrochloride is a potent and highly selective histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 71 nM, 19 nM, 69 nM, 69 nM for KDM5A, KDM5B, KDM5C, KDM5D, respectively.
价 格:¥电议型 号:T11750L产 地:中国大陆
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T11739K145;化合物 T11739K145
K145 is inactive against SphK1 and other protein kinases. K145 induces cell apoptosis and has potently antitumor activity. K145 is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC50 of 4.3 μM and a Ki of 6.4 μM.
价 格:¥电议型 号:T11739产 地:中国大陆
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T11737K-Ras G12C-IN-3;化合物 T11737K-Ras G12C-IN-3
Heterocyclic compounds as covalent inhibitors of G12C mutant K-Ras protein useful for treating cancers.K-Ras G12C-IN-3 is a novel and irreversible inhibitor of mutant K-ras G12C.
价 格:¥电议型 号:T11737产 地:中国大陆
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T11736K-Ras G12C-IN-2;化合物 T11736K-Ras G12C-IN-2
K-Ras G12C-IN-2 is a covalent kras g12c inhibitor.
价 格:¥电议型 号:T11736产 地:中国大陆
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T11735K-Ras G12C-IN-1;化合物 T11735K-Ras G12C-IN-1
K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C.
价 格:¥电议型 号:T11735产 地:中国大陆
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T11734K-80003;化合物K-80003TX-803;TX-803
K-80003(TX-803) is a potent retinol-like X-receptor-alpha regulator that inhibits TRxrα-dependent Akt activation and tumor cell growth.
价 格:¥电议型 号:T11734产 地:中国大陆
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T11733K-604 dihydrochloride;化合物K-604 dihydrochlorideK-604 dihydrochloride
K-604 dihydrochloride is a potent and selective acyl-CoA:cholesterol acyltransferase 1 inhibitor with an IC50 of 0.45±0.06 μM.
价 格:¥电议型 号:T11733产 地:中国大陆
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T11732JTV-519 hemifumarate;化合物 T11732K201 hemifumarate;K201 hemifumarate
JTV-519 hemifumarate,Antiarrhythmic and cardioprotective properties. is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle.
价 格:¥电议型 号:T11732产 地:中国大陆
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T11731LJTV-519 Formate;化合物JTV-519 FormateJTV-519 Formate (145903-06-6 Free base);JTV-519 Formate (145903-06
JTV-519 Formate is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA). JTV-519 Formate is also a partial agonist of ryanodine receptors in striated muscle. JTV-519 Formate exhibits antiarrhythmic and cardioprotective properties.
价 格:¥电议型 号:T11731L产 地:中国大陆
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T11731JTV-519 free base;化合物 T11731K201 free base;K201 free base
JTV-519 free base (K201 free base), recognized for its antiarrhythmic and cardioprotective properties, functions as a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and serves as a partial agonist of ryanodine receptors in striated muscle.
价 格:¥电议型 号:T11731产 地:中国大陆
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T11730JTT 551;化合物 T11730JTT551|||JTT 551|||JTT-551|||JTT 551;JTT551|||JTT 551|||JTT-551|||JTT 551
JTT 551 can be used in the research of type 2 diabetes mellitus. JTT 551 is selective a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with Kis of 0.22 μM and 9.3 μM for PTP1B and TCPTP (T-cell protein tyrosine phosphatase), respectively.
价 格:¥电议型 号:T11730产 地:中国大陆
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T1173Tropisetron hydrochloride;盐酸托烷司琼SDZ-ICS 930|||Tropisetron HCl|||ICS 205-930;SDZ-ICS 930|||Tropisetro
Tropisetron hydrochloride (Tropisetron HCl) is the hydrochloride salt form of tropisetron, a selective, competitive serotonin 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist, with antinauseant and antiemetic activities.
价 格:¥电议型 号:T1173产 地:中国大陆
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T1169Moguisteine莫吉司坦莫吉司坦|||BBR-2173
Moguisteine (BBR-2173) is a new-type peripheral non-narcotic antitussive drug.
价 格:¥电议型 号:T1169产 地:中国大陆
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T11673IRAK4-IN-4;化合物IRAK4-IN-4IRAK4-IN-4
IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM.
价 格:¥电议型 号:T11673产 地:中国大陆
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T11585Hydroxy Itraconazole D8;化合物 T11585R-63373 D8;R-63373 D8
Hydroxy Itraconazole D8 is the deuterium-labeled Hydroxy Itraconazole. Hydroxy Itraconazole is an active metabolite of Itraconazole, which is a triazole antifungal agent.
价 格:¥电议型 号:T11585产 地:中国大陆
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T11573HPN-01;化合物 T11573HPN-01
HPN-01 is a selective IKK inhibitor (pIC50s: 6.4, 7.0, and <4.8 for IKK-α, IKK-β, and IKK-ε). HPN-01 displays greater 50-fold selectivity over a panel of more than 50 other kinases, including ALK5, CDK-2, ErbB2, EGFR, GSK3β, Src, PLK1, and VEGFR-2.
价 格:¥电议型 号:T11573产 地:中国大陆
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T11514Gusperimus trihydrochloride;化合物 T11514NKT-01|||BMS181173|||Spanidin;NKT-01|||BMS181173|||Spanidin
Gusperimus trihydrochloride is a derivative of the antitumor antibiotic spergualin with immunosuppressant activity.
价 格:¥电议型 号:T11514产 地:中国大陆
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T11491GSK2973980A;化合物 T11491GSK2973980A
GSK2973980A is a selective Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitor (IC50: 3 nM).
价 格:¥电议型 号:T11491产 地:中国大陆
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T11450Gosogliptin;化合物 T11450PF-00734200|||PF-734200;PF-00734200|||PF-734200
Gosogliptin is a potent and selective dipeptidyl peptidase-IV (DPP-IV) inhibitor.
价 格:¥电议型 号:T11450产 地:中国大陆
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T11393GET73;化合物GET73Gamma hydroxybutyric acid analogue|||GET 73;Gamma hydroxybutyric acid analogue|||GET 7
GET73 (Gamma hydroxybutyric acid analogue) is an negative allosteric modulator of mGluR5. GET73 is a naturally occurring neurotransmitter. GET73 has anti-alcohol and anxiolytic properties.
价 格:¥电议型 号:T11393产 地:中国大陆