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T10737CDK4/6-IN-3;化合物 T10737CDK4/6-IN-3
CDK4/6-IN-3 is a brain-penetrant CDK4/CDK6 inhibitor (Kis: <0.3 nM and 2.2 nM) used for the treatment of glioblastoma. It inhibits CDK1 with a Ki of 110 nM.
价 格:¥电议型 号:T10737产 地:中国大陆
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T10735CDK4/6/1 Inhibitor;CDK4/6/1抑制剂Crozbaciclib;Crozbaciclib
CDK4/6/1 Inhibitor (Crozbaciclib) is a type of CDK4/6 inhibitor (IC50s: 3 and 1 nM). CDK4/6 inhibitor is a class of compounds used for the treatment of some types of hormone receptor positive, HER2-negative breast cancer, which can block the process of breast cancer cell division and reproduction.
价 格:¥电议型 号:T10735产 地:中国大陆
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T10734CDK ligand for PROTAC;化合物 T10734CDK ligand for PROTAC
CDK ligand for PROTAC is a CDK inhibitor with antitumor activity. It has been used to design PROTAC CDK4/6 degraders.
价 格:¥电议型 号:T10734产 地:中国大陆
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T10733CDDO-EA;化合物CDDO-EATP319|||CDDO ethyl amide|||RTA 405;TP319|||CDDO ethyl amide|||RTA 405
CDDO-EA (CDDO ethyl amide) is an activator of the Nrf2/antioxidant response element.
价 格:¥电议型 号:T10733产 地:中国大陆
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T10732Tematropium;化合物TematropiumCDDD3602|||Tematropium metilsulfate|||HGP6;CDDD3602|||Tematropium metilsul
Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.
价 格:¥电议型 号:T10732产 地:中国大陆
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T10731CDD0102;化合物 T10731CDD0102A;CDD0102A
CDD0102 is a potent agonist of M1 Muscarinic receptor.
价 格:¥电议型 号:T10731产 地:中国大陆
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T10730CDC801;化合物CDC801CDC-801;CDC-801
CDC801 is an inhibitor of PDE4 and TNF-α with IC50s of 1.1 μM and 2.5 μM, respectively.
价 格:¥电议型 号:T10730产 地:中国大陆
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T1073Dronedarone hydrochloride;盐酸决奈达隆Dronedarone HCl|||SR33589;Dronedarone HCl|||SR33589|||决奈达隆盐酸盐|||盐酸决奈
Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.
价 格:¥电议型 号:T1073产 地:中国大陆
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T10721CD73-IN-1;CD73 抑制剂1CD73-IN-1
CD73-IN-1 is a CD73 inhibitor with anticancer activity.
价 格:¥电议型 号:T10721产 地:中国大陆
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T10699L2CBB1007 trihydrochloride (1379573-92-8 free base);化合物 T10699L2CBB1007 trihydrochloride;CBB1007 trihy
CBB1007 trihydrochloride is a selective, reversible, and substrate competitive LSD1 inhibitor (IC50: 5.27 μM for hLSD1).
价 格:¥电议型 号:T10699L2产 地:中国大陆
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T10699CBB1007 hydrochloride (1379573-92-8 free base);化合物 T10699CBB1007 hydrochloride;CBB1007 hydrochloride
CBB1007 Hcl is a selective, reversible, and substrate competitive LSD1 inhibitor (IC50: 5.27 μM for hLSD1).
价 格:¥电议型 号:T10699产 地:中国大陆
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T10698LCBB1003 hydrochloride (1379573-88-2 free base);化合物 T10698LCBB1003 hydrochloride;CBB1003 hydrochlorid
CBB1003 hydrochloride is a new inhibitor of histone demethylase LSD1 (IC50: 10.54 μM).
价 格:¥电议型 号:T10698L产 地:中国大陆
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T10692CB-1158 dihydrochloride (2095732-06-0 free base);化合物 T10692INCB01158 dihydrochloride|||CB-1158 dihyd
CB-1158 dihydrochloride is an effective and orally active inhibitor of arginase (IC50s: 86 nM and 296 nM for recombinant human arginase 1 and 2).
价 格:¥电议型 号:T10692产 地:中国大陆
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T10673Carbacyclin;化合物 T10673Carbaprostacyclin|||Carba-PGI2;Carbaprostacyclin|||Carba-PGI2
Carbacyclin, a PGI2 analog, is a prostacyclin (PGI2) receptor agonist and vasodilator with potent inhibitory platelet aggregation.
价 格:¥电议型 号:T10673产 地:中国大陆
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T10613BRL 37344 sodium;化合物 T10613BRL 37344A;BRL 37344A
BRL 37344 sodium is a specific agonist of the β3-adrenergic receptor. The treatment of BRL 37344 sodium significantly lowers the bodyweight of obese mice.
价 格:¥电议型 号:T10613产 地:中国大陆
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T10573BMT-145027;化合物BMT-145027BMT-145027
BMT-145027 is a positive allosteric modulator of mGluR5 without inherent agonist activity (EC50 = 47 nM).
价 格:¥电议型 号:T10573产 地:中国大陆
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T10564(8R,9S)-Talazoparib;他拉唑帕利 (8R,9S)(8R,9S)-BMN-673;(8R,9S)-BMN-673|||他拉唑帕利 (8R,9S)
(8R,9S)-Talazoparib is Talazoparib enantiomer , less active than Talazoparib on the inhibition of PARP1 (IC50: 144 nM).
价 格:¥电议型 号:T10564产 地:中国大陆
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T10481LBAY 73-6691;化合物 T10481L(R)-BAY 73-6691;(R)-BAY 73-6691
BAY 73-6691 is an inhibitor of brain penetrant PDE9A.
价 格:¥电议型 号:T10481L产 地:中国大陆
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T10481BAY 73-6691 racemate;化合物 T10481BAY 73-6691 racemate
BAY 73-6691 racemate is a phosphodiesterase 9 inhibitor.
价 格:¥电议型 号:T10481产 地:中国大陆
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T10473LBAY-677;化合物 T10473LBAY-677
BAY-677, serving as an inactive control for BAY-678, is distinguished by BAY-678´s capabilities as an orally bioavailable, selective, and cell-permeable inhibitor of human neutrophil elastase (HNE), showcasing a high potency with an IC50 of 20 nM[1]. Furthermore, BAY-678 has been publicly nominated as a chemical probe by the Structural Genomics Consortium (SGC)[2].
价 格:¥电议型 号:T10473L产 地:中国大陆