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T10473BAY-678;化合物BAY-678BAY-678
BAY-678 is a human neutrophil elastase (HNE; IC50: 20 nM) inhibitor with oral bioactivity, potency and selectivity.BAY-678 is a chemical probe recommended by the Structural Genomics Consortium (SGC).
价 格:¥电议型 号:T10473产 地:中国大陆
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T1046Mexiletine hydrochloride;盐酸美西律KOE-1173 (hydrochloride)|||Mexiletine HCl|||KO1173;KOE-1173 (hydrochlo
Mexiletine hydrochloride (KOE-1173 hydrochloride) is a voltage-gated sodium channel blocker and a Class IB antiarrhythmic drug. Mexiletine hydrochloride exerts antiarrhythmic effects by inhibiting sodium current in myocardial cells, thereby reducing the rise rate of cardiac action potential (phase 0) and reducing the automaticity of Purkinje fibers.
价 格:¥电议型 号:T1046产 地:中国大陆
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T10447BAA473;化合物 T10447BAA473
BAA473 is a bile acid analog that is a potent activator of the pyrin inflammasome. BAA473 can induce secretion of interleukin-18 (IL-18) through activation of the inflammasome in both myeloid and intestinal epithelial cells [1].
价 格:¥电议型 号:T10447产 地:中国大陆
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T10436LAZD4573 HCl (2057509-72-3 free base);化合物 T10436LAZD4573 hydrochloride|||AZD4573|||AZD4573 HCl|||AZD-
AZD-4573 is a selective and short-acting inhibitor of the serine/threonine cyclin-dependent kinase 9, the catalytic subunit of the RNA polymerase II elongation factor positive transcription elongation factor b. It also has a potential antineoplastic activity.
价 格:¥电议型 号:T10436L产 地:中国大陆
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T10436AZD4573;化合物AZD4573AZD4573
AZD4573 is an effective and selective CDK9 inhibitor (IC50: <4 nM). It enables transient target engagement for the treatment of hematologic malignancies.
价 格:¥电议型 号:T10436产 地:中国大陆
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T10373(R)-Filanesib;化合物 T10373(R)-ARRY-520;(R)-ARRY-520
(R)-Filanesib is the R-enantiomer of ARRY-520. (R)-Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor (IC50: 6 nM).
价 格:¥电议型 号:T10373产 地:中国大陆
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T10338Antisauvagine-30 TFA (220673-95-0 free base);化合物 T10338Antisauvagine-30 TFA|||aSvg-30 TFA;Antisauvag
Antisauvagine-30 TFA (aSvg-30 TFA) is a highly selective and competitive antagonist of CRF2 receptor peptidic. It shows a Kd of 1.4 nM and 150 nM for mCRFR2β and CRFR1, respectively.
价 格:¥电议型 号:T10338产 地:中国大陆
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T10273AhR modulator-1;化合物 T10273AhR modulator-1
AhR modulator-1 is a selective and orally active aryl hydrocarbon receptor (AhR) modulator. It inhibits metastasis, in part, by inhibiting prostatic VEGF production prior to tumor formation. It also possesses anti-estrogenic properties in rat uterus.
价 格:¥电议型 号:T10273产 地:中国大陆
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T101886RK73;化合物6RK736RK73
6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 ?M). 6RK73 shows almost no inhibition of UCHL3 (IC50: 236 ?M).
价 格:¥电议型 号:T10188产 地:中国大陆
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T10173MCHR1 antagonist 1;化合物 T10173MCHR1 antagonist 1
MCHR1 antagonist 1 is a selective antagonist of melanin-concentrating hormone-1 (MCH1) receptor (Kb: 1 nM, Ki: 4 nM at human MCH1).
价 格:¥电议型 号:T10173产 地:中国大陆
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T10096L2(2S,3R)-Voruciclib hydrochloride;化合物 T10096L2(2S,3R)-Voruciclib hydrochloride (1253731-24-6 free bas
(2S,3R)-Voruciclib hydrochloride is the (2S,3R)-enantiomer of Voruciclib. It is an orally active CDK inhibitor.
价 格:¥电议型 号:T10096L2产 地:中国大陆
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T100732-Iodomelatonin;2-碘褪黑激素2-Iodomelatonin
2-Iodomelatonin is a potent agonist of melatonin receptor 1 (MT1) with a Ki value of 28 pM, it is more 5-fold selective for MT1 over MT2. 2-iodomelatonin can be used to identify, characterize and localize melatonin binding sites in the brain and peripheral tissues.
价 格:¥电议型 号:T10073产 地:中国大陆
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T0973LPyridoxine hydrochloride;吡哆醇盐酸盐Pyridoxine HCl|||Pyridoxol (hydrochloride)|||Vitamin B6 (hydrochlorid
Pyridoxine hydrochloride (Vitamin B6) is the 4-methanol form of vitaminB6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid.
价 格:¥电议型 号:T0973L产 地:中国大陆
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T0973Pyridoxine;吡哆醇Pyridoxol|||Vitamin B6|||Gravidox;吡哆醇|||Pyridoxol|||Vitamin B6|||Gravidox|||吡多素(维生素B6)
Pyridoxine (Vitamin B6) is the 4-methanol form of vitamin B6 and is converted to pyridoxal 5-phosphate in the body. Although pyridoxine and vitamin B6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading.
价 格:¥电议型 号:T0973产 地:中国大陆
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T0968Paclitaxel;紫杉醇Taxol|||NSC 125973;Taxol|||紫杉醇|||NSC 125973
Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer. Paclitaxel has anti-tumor activity and causes cell death by inducing mitotic arrest, apoptosis, and cell autophagy.
价 格:¥电议型 号:T0968产 地:中国大陆
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T0890Mefenamic acid;甲芬那酸CN-35355|||CI 473;CN-35355|||CI 473|||甲芬那酸|||甲灭酸
Mefenamic acid (CN-35355) is a non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
价 格:¥电议型 号:T0890产 地:中国大陆
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T0873Dinitolmide;二硝托胺Zoalene;二硝托胺|||Zoalene
Dinitolmide (Zoalene), a poultry feed additive, is a coccidiostat for poultry.
价 格:¥电议型 号:T0873产 地:中国大陆
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T0786Clidinium bromide;克利溴铵Ro 2-3773;克利溴铵|||Ro 2-3773
Clidinium bromide (Ro 2-3773) , a synthetic anticholinergic agent, has been shown in experimental and clinical researchers to have a pronounced antisecretory and antispasmodic effect on the gastrointestinal tract. It can inhibit muscarinic actions of acetylcholine at postganglionic parasympathetic neuroeffector sites. It is used for the treatment of peptic ulcer disease and also to help relieve cramps or stomach spasms or abdominal due to colicky abdominal diverticulitis, pain, and irritable bow
价 格:¥电议型 号:T0786产 地:中国大陆
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T0777Tilmicosin;替米考星LY-177370|||EL-870;LY-177370|||替米考星|||EL-870
Tilmicosin (EL-870) is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia haemolytica.
价 格:¥电议型 号:T0777产 地:中国大陆
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T0773Febuxostat;非布司他TMX 67|||TEI 6720;非布索坦|||TMX 67|||非布司他|||TEI 6720
Febuxostat (TEI 6720) is a xanthine oxidase Inhibitor.
价 格:¥电议型 号:T0773产 地:中国大陆