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T10297LAMG 487;化合物AMG 487AMG 487
AMG 487 is a potent and selective antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively.
价 格:¥电议型 号:T10297L产 地:中国大陆
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T10297AMG 487 (S-enantiomer);化合物 T10297AMG 487 (S-enantiomer)
AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an CXCR3 antagonist.
价 格:¥电议型 号:T10297产 地:中国大陆
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T10296Mavorixafor trihydrochloride;化合物 T10296AMD-070 trihydrochloride;AMD-070 trihydrochloride
Mavorixafor trihydrochloride is a selective and orally available CXCR4 antagonist (IC50: 13 nM against CXCR4 125I-SDF binding) and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs (IC50s: 1 and 9 nM).
价 格:¥电议型 号:T10296产 地:中国大陆
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T10290LAlpertine HCl;阿尔哌汀盐酸盐Win 31665 HCl|||Alpertine HCl(27076-46-6 Free base);Win 31665 HCl|||Alpertine H
Alpertine HCl is a small molecule compound with anti-neuropathic properties.
价 格:¥电议型 号:T10290L产 地:中国大陆
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T1029Aztreonam;氨曲南SQ-26,776;SQ-26,776|||氨曲南
Aztreonam (SQ-26,776) is a monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum with bactericidal activity.
价 格:¥电议型 号:T1029产 地:中国大陆
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T10289Alosetron ((Z)-2-butenedioate);马来酸阿洛司琼GR 68755 ((Z)-2-butenedioate)|||GR 68755X ((Z)-2-butenedioate)
Alosetron (GR 68755) (Z)-2-butenedioate is a Serotonin 5HT3-receptor antagonist that is used in the treatment of irritable bowel syndrome.
价 格:¥电议型 号:T10289产 地:中国大陆
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T10287ALK2-IN-2;化合物ALK2-IN-2ALK2-IN-2
ALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) (IC50: 9 nM), inhibiting ALK2 700-fold more than ALK3.
价 格:¥电议型 号:T10287产 地:中国大陆
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T10279Alfacalcidol-D6;化合物 T10279Alfacalcidol-D6
Alfacalcidol-D6 is a deuterated Alfacalcidol. Alfacalcidol is a non-selective VDR activator medication.
价 格:¥电议型 号:T10279产 地:中国大陆
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T10278Alamethicin;丙甲菌素Alamethicin
Alamethicin is isolated from Trichoderma viride. It is a channel-forming peptide antibiotic and induces voltage-gated conductance in model and cell membranes.
价 格:¥电议型 号:T10278产 地:中国大陆
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T10277AL 8697;化合物AL 8697AL 8697
AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases. AL 8697 has anti-inflammatory activity.
价 格:¥电议型 号:T10277产 地:中国大陆
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T10276LAKT Kinase Inhibitor HCl;AKT Kinase抑制剂盐酸盐AKT Kinase Inhibitor HCl(842148-40-7 Free base);AKT Kinase
AKT Kinase Inhibitor HCl is an Akt inhibitor with antitumor activity.
价 格:¥电议型 号:T10276L产 地:中国大陆
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T10276AKT Kinase Inhibitor;AKT激酶抑制剂AKT Kinase Inhibitor
AKT Kinase Inhibitor is an Akt inhibitor with antitumor activity that selectively inhibits cell proliferation in a dose-dependent manner.
价 格:¥电议型 号:T10276产 地:中国大陆
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T10275AKT-IN-3;化合物 T10275AKT-IN-3
AKT-IN-3 is a potent, orally active low hERG blocking Akt inhibitor (IC50: 1.4 nM, 1.2 nM, and 1.7 nM for Akt1, Akt2, and Akt3). AKT-IN-3 (compound E22) also exhibits good inhibitory activity against other AGC family kinases, such as PKA, PKC, ROCK1, RSK1, P70S6K, and SGK.
价 格:¥电议型 号:T10275产 地:中国大陆
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T10274AKT-IN-2;化合物 T10274AKT-IN-2
AKT-IN-2 is a selective, and orally bioavailable AKT inhibitor (IC50: 5 nM for AKT1).
价 格:¥电议型 号:T10274产 地:中国大陆
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T10273AhR modulator-1;化合物 T10273AhR modulator-1
AhR modulator-1 is a selective and orally active aryl hydrocarbon receptor (AhR) modulator. It inhibits metastasis, in part, by inhibiting prostatic VEGF production prior to tumor formation. It also possesses anti-estrogenic properties in rat uterus.
价 格:¥电议型 号:T10273产 地:中国大陆
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T10272AHR antagonist 5;化合物 T10272AHR antagonist 5
AHR antagonist 5 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist(example 39; IC50 < 0.5 μΜ). It significantly inhibits tumor growth combined with checkpoint inhibitor anti-PD-1.
价 格:¥电议型 号:T10272产 地:中国大陆
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T10271AHR antagonist 4;化合物 T10271AHR antagonist 4
AHR antagonist 4 is a potent aryl hydrocarbon receptor (AHR) antagonist(example 293; IC50: 82.2 nM).It has anti-cancer effects.
价 格:¥电议型 号:T10271产 地:中国大陆
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T10270BAY 2416964;化合物BAY 2416964BAY 2416964
BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist(example 192, IC50: 341 nM). It has the potential for cancer treatment.
价 格:¥电议型 号:T10270产 地:中国大陆
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T1027Luteolin;木犀草素Luteolol|||Flacitran|||Digitoflavone|||Luteoline;木犀草素|||Luteolol|||Flacitran|||Digitofl
Luteolin (Luteolol) belongs to the flavonoid group of natural products and is a Nrf2 inhibitor, PDE inhibitor. Luteolin has a wide range of biological activities including antitumor, antioxidant, anti-inflammatory, antimicrobial, antiviral, antiallergic, and procoagulant.
价 格:¥电议型 号:T1027产 地:中国大陆
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T10267Agomelatine (L(+)-Tartaric acid);阿戈美拉汀 L(+)-酒石酸S-20098 L(+)-Tartaric acid;阿戈美拉汀 L(+)-酒石酸|||S-20098 L
Agomelatine (S-20098) L(+)-Tartaric acid is a specific agonist of MT1 and MT2 receptors (Kis: 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2). It also is a selective 5-HT2C receptor antagonist (pKis: 6.4 and 6.2 at native (porcine) and cloned (human) 5-HT2C receptors).
价 格:¥电议型 号:T10267产 地:中国大陆