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T12046Mirtazapine D3;米氮平 D3Org3770 D3|||6-Azamianserin D3;Org3770 D3|||6-Azamianserin D3|||米氮平 D3
Mirtazapine D3 is a deuterium labeled Mirtazapine. Mirtazapine is an inhibitor of 5-HT receptor .
价 格:¥电议型 号:T12046产 地:中国大陆
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T11970MCL-1/BCL-2-IN-3;化合物 T11970MCL-1/BCL-2-IN-3
MCL-1/BCL-2-IN-3 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectiely.
价 格:¥电议型 号:T11970产 地:中国大陆
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T1193Clomiphene citrate;枸橼酸氯米芬NSC 35770|||Clomifene citrate;NSC 35770|||枸橼酸氯米芬|||Clomifene citrate
Clomiphene citrate (NSC 35770) is a selective estrogen receptor modulator.
价 格:¥电议型 号:T1193产 地:中国大陆
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T11900LY-2584702 hydrochloride;化合物 T11900LY-2584702 hydrochloride
Ly-2584702 hydrochloride is a p70S6K selective ATP competitive inhibitor with IC50 of 4 nM.In the S6K1 enzyme assay, the IC50 of LY-2584702 was 2 nM.
价 格:¥电议型 号:T11900产 地:中国大陆
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T11872LLMP744 hydrochloride;化合物LMP744 hydrochlorideNSC706744 hydrochloride|||MJ-III65 hydrochloride;NSC7067
LMP744 hydrochloride (NSC-706744 hydrochloride) is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity.?
价 格:¥电议型 号:T11872L产 地:中国大陆
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T11872LMP744;化合物 T11872NSC706744|||MJ-III65;NSC706744|||MJ-III65
LMP744 is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity.
价 格:¥电议型 号:T11872产 地:中国大陆
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T11870Losartan D4;氯沙坦 D4DuP-753 D4;氯沙坦 D4|||DuP-753 D4
Losartan D4, the deuterium-labeled version of Losartan, functions as an angiotensin II receptor antagonist. It inhibits the interaction between angiotensin II and AT1 receptors by competing for binding, achieving an IC50 value of 20 nM.
价 格:¥电议型 号:T11870产 地:中国大陆
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T11799LL-745870;化合物 T11799LL-745870
L-745870 is a high-affinity and selective human dopamine D4 receptor antagonist (Ki: 0.43 nM). L-745870 has excellent brain penetration. It considerably weaker D2 (Ki: 960 nM) and D3 (Ki: 2300 nM) receptors affinity.
价 格:¥电议型 号:T11799L产 地:中国大陆
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T11799L-745870 hydrochloride;化合物L-745870 hydrochlorideL-745870 hydrochloride
L-745870 hydrochloride has excellent brain penetration.?L-745870 hydrochloride is a high-affinity, selective and orally active human dopamine D4 receptor antagonist with a Ki of 0.43 nM, and considerably weaker D2 receptor affinity with a Ki of 960 nM and D3 receptor affinity with a Ki of 2300 nM.?
价 格:¥电议型 号:T11799产 地:中国大陆
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T11770KRAS G12C inhibitor 16;化合物 T11770KRAS G12C inhibitor 16
KRAS G12C inhibitor 16 is a potent KRAS G12C inhibitor.
价 格:¥电议型 号:T11770产 地:中国大陆
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T11766LEltanexor;化合物EltanexorONO-7706|||KPT-8602|||ATG-016;ONO-7706|||KPT-8602|||ATG-016
Eltanexor (ONO-7706) is an orally active exportin-1 (XPO1) inhibitor. It has effective anti-leukemic activity. Eltanexor inhibits XPO1-dependent nuclear export (EC50=60.9 nM) by directly targeting XPO1. Eltanexor causes caspase-dependent apoptosis in a panel of leukemic cell lines.
价 格:¥电议型 号:T11766L产 地:中国大陆
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T11725JNJ-47117096 hydrochloride;化合物 T11725MELK-T1 hydrochloride;MELK-T1 hydrochloride
JNJ-47117096 hydrochloride is potent and selective MELK inhibitor, with an IC50 of 23 nM, also effectively inhibits Flt3, with an IC50 of 18 nM.
价 格:¥电议型 号:T11725产 地:中国大陆
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T11709JAK3 covalent inhibitor-1;化合物 T11709JAK3 covalent inhibitor-1
JAK3 Covalent Inhibitor-1 is a compound characterized by its potent and selective inhibition of Janus kinase 3 (JAK3), possessing an IC50 of 11 nM and demonstrating a 246-fold selectivity compared to other JAKs.
价 格:¥电议型 号:T11709产 地:中国大陆
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T11708JAK2-IN-4;化合物 T11708JAK2-IN-4
JAK2-IN-4 is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM for JAK2 and JAK3, respectively.
价 格:¥电议型 号:T11708产 地:中国大陆
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T11707JAK2/FLT3-IN-1;化合物 T11707JAK2/FLT3-IN-1
JAK2/FLT3-IN-1 has anti-cancer activity. JAK2/FLT3-IN-1 is a potent and orally effective dual JAK2/FLT3 (Janus kinase 2/ FMS-like tyrosine kinase 3) inhibitor with IC50 values of 0.7 nM, 4 nM, 26 nM and 39 nM for JAK2, FLT3, JAK1 and JAK3, respectively.
价 格:¥电议型 号:T11707产 地:中国大陆
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T11706Londamocitinib;化合物LondamocitinibAZD4604;AZD4604
Londamocitinib (JAK1-IN-7) is a selective and potent JAK1 inhibitor with anti-inflammatory activity.
价 格:¥电议型 号:T11706产 地:中国大陆
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T11705JAK-IN-4;化合物 T11705JAK-IN-4
JAK-IN-4 is a prodrug of a JAK inhibitor, effective in murine collagen induced arthritis model.
价 格:¥电议型 号:T11705产 地:中国大陆
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T11704JAK-IN-3;化合物 T11704JAK-IN-3
JAK-IN-3 is a potent JAK inhibitor, with IC50 values of 3 nM, 5 nM, 34 nM and 70 nM for JAK3, JAK1, TYK2 and JAK2, respectively.
价 格:¥电议型 号:T11704产 地:中国大陆
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T11703JAK-IN-1;化合物 T11703JAK-IN-1
JAK-IN-1 shows improved selectivity for JAK3 over JAK1. JAK-IN-1 is a JAK1/2/3 inhibitor with IC50s of 0.26, 0.8 and 3.2 nM, respectively.
价 格:¥电议型 号:T11703产 地:中国大陆
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T11702J30-8;化合物 T11702J30-8
J30-8, a potent and isoform-selective c-Jun N-terminal kinase 3 (JNK3) inhibitor with an IC50 of 40 nM and 2500-fold isoform selectivity against JNK1α1 and JNK2α2, exhibits neuroprotective activity in vitro and shows promise for treating neurodegenerative diseases.
价 格:¥电议型 号:T11702产 地:中国大陆