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T11011Dexpramipexole dihydrochloride;右旋普拉克索二盐酸盐KNS-760704 dihydrochloride|||R-(+)-Pramipexole dihydrochlor
Dexpramipexole dihydrochloride (KNS-760704 dihydrochloride) ((R)-Pramipexole dihydrochloride) is a neuroprotective agent and is a weak non-ergoline dopamine agonist.
价 格:¥电议型 号:T11011产 地:中国大陆
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T11007LLevofloxacin Hydrochloride Impurity A;左氧氟沙星杂质A(盐酸盐)Levofloxacin Hydrochloride Impurity A(117707-40-1
Levofloxacin Hydrochloride Impurity A I, one of the quinolones, has a broad spectrum of antibacterial action.
价 格:¥电议型 号:T11007L产 地:中国大陆
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T10970DC1;化合物 T10970DC1
DC1 can be used to synthesize antibody-drug conjugates targeted to the treatment of cancer, is an ADC cytotoxin, similar to the small groove-binding DNA alkylating agent CC-1065.
价 格:¥电议型 号:T10970产 地:中国大陆
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T10898Samuraciclib hydrochloride;化合物Samuraciclib hydrochlorideICEC0942 hydrochloride|||CT7001 hydrochlorid
Samuraciclib hydrochloride (ICEC0942 hydrochloride) is a potent, selective, ATP competitive and oral active CDK7 inhibitor with IC50 of 41 nM. The selectivity of Samuraciclib hydrochloride is 45-, 15-, 230- and 30-fold higher than CDK1, CDK2 (IC50 is 578 nM), CDK5 and CDK9 respectively. Samuraciclib hydrochloride inhibits the growth of breast cancer cell lines with GI50 values between 0.2-0.3 μM. Samuraciclib hydrochloride has anti-tumor effects.
价 格:¥电议型 号:T10898产 地:中国大陆
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T10870LCP-547632;化合物CP-547632CP-547632
CP-547632 is an orally available and potent, ATP-competitive dual inhibitor of VEGFR-2 and FGF kinase F with IC50s of 11 nM and 9 nM, respectively. CP-547632 is selective, with higher selectivity for VEGFR2 and bFGF than for EGFR, PDGFRβ and related tyrosine kinases (TKs). PDGFRβ and related tyrosine kinases (TKs) CP-547632 has antitumour activity.
价 格:¥电议型 号:T10870L产 地:中国大陆
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T10870CP-547632 hydrochloride;化合物 T10870CP-547632 hydrochloride
CP-547632 hydrochloride is a well-tolerated and orally-bioavailable inhibitor of the VEGFR-2 and basic FGF kinases (IC50s: 11 nM and 9 nM) with antitumor efficacy.
价 格:¥电议型 号:T10870产 地:中国大陆
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T10840CM-579 trihydrochloride (1846570-40-8 free base);化合物 T10840CM-579 trihydrochloride;CM-579 trihydroch
CM-579 trihydrochloride is a first-in-class reversible and dual inhibitor of G9a and DNMT (IC50s: 16 nM, 32 nM) with potent in vitro cellular activity in a wide range of cancer cells.
价 格:¥电议型 号:T10840产 地:中国大陆
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T10809LCHPG hydrochloride;化合物CHPG盐酸盐CHPG hydrochloride(170846-74-9 Free base);CHPG hydrochloride(170846-74-
CHPG hydrochloride is a selective agonist of mGluR5.
价 格:¥电议型 号:T10809L产 地:中国大陆
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T10770Cetirizine D8;化合物 T10770Cetirizine D8
Cetirizine D8 is a deuterium-labeled Cetirizine. Cetirizine is a second-generation antihistamine and a long-acting histamine H1-receptor antagonist.
价 格:¥电议型 号:T10770产 地:中国大陆
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T1070LCefmetazole;化合物 T1070LSodium, Cefmetazole|||Cefmetazolum|||Cefmetazolo;Sodium, Cefmetazole|||Cefmeta
Cefmetazole is a second-generation semi-synthetic β-lactam cephalosporin antibiotic with antimicrobial activity.
价 格:¥电议型 号:T1070L产 地:中国大陆
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T10709CCR1 antagonist 7;化合物 T10709CCR1 antagonist 7
CCR1 antagonist 7 (compound 16r) is an antagonist of chemokine receptor 1 (CCR1) with an IC 50 of 4 nM [1].
价 格:¥电议型 号:T10709产 地:中国大陆
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T10708CCR1 antagonist 6;CCR1拮抗剂6CCR1 antagonist 6
CCR1 antagonist 6 is a CCR1 antagonist (IC50: 3 nM).
价 格:¥电议型 号:T10708产 地:中国大陆
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T10707CCK-B Receptor Antagonist 2;化合物 T10707CCK-B Receptor Antagonist 2
CCK-B Receptor Antagonist 2 is a potent and orally active antagonist of Gastrin/CCK-B (IC50: 0.43 nM). It also inhibits gastrin/CCK-A activity (IC50: 1.82 μM).
价 格:¥电议型 号:T10707产 地:中国大陆
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T10706CCI-006;化合物CCI-006CCI-006
CCI-006, a selective inhibitor and chemosensitizer for MLL-rearranged leukemia cells, disrupts mitochondrial respiration. This action leads to irreversible mitochondrial depolarization and triggers a pro-apoptotic unfolded protein response in specific MLL-r leukemia cells.
价 格:¥电议型 号:T10706产 地:中国大陆
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T10705CCG 203769;化合物CCG 2037694-butyl-2-ethyl-1,2,4-thiadiazolidine-3,5-dione|||RGS4 inhibitor 11b|||Thiad
CCG 203769 (Thiadiazolidinone (TDZD) deriv. 6) is a selective inhibitor of RGS4 with an IC50 of 17 nM for the RGS4-Gαo protein-protein interaction.
价 格:¥电议型 号:T10705产 地:中国大陆
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T10704CCB02;化合物CCB02CCB02
CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity. CCB02 shows no inhibition on the cell cycle- and centrosome-related kinases, or the phosphorylation status of Aurora-A, CDK2, Plk1, Plk2, and CHK1.
价 格:¥电议型 号:T10704产 地:中国大陆
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T10703Mezigdomide;化合物 MezigdomideCC-92480;CC-92480
Mezigdomide (CC-92480) is a potent, novel, selective and active cereblon E3 ubiquitin ligase modulator (CELMoD) that often acts as a molecular glue. Mezigdomide has antimyeloma activity.
价 格:¥电议型 号:T10703产 地:中国大陆
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T10702CBP/p300-IN-2;化合物 T10702CBP/EP300-IN-2;CBP/EP300-IN-2
CBP/EP300-IN-2 is an inhibitor of CBP/EP300 (IC50s: 1.07 nM and 5.96 nM for CBP/HTRF and Myc).
价 格:¥电议型 号:T10702产 地:中国大陆
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T10701(+)-CBI-CDPI2;化合物 T10701(+)-CBI-CDPI2
(+)-CBI-CDPI2 is an enhanced functional analog of CC-1065.
价 格:¥电议型 号:T10701产 地:中国大陆
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T10700(+)-CBI-CDPI1;化合物 T10700(+)-CBI-CDPI1
(+)-CBI-CDPI1 is an enhanced functional analog of CC-1065. It is a DNA alkylating agent and an antibody-drug conjugates (ADCs) toxin.
价 格:¥电议型 号:T10700产 地:中国大陆