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T1070Cefmetazole sodium;头孢美唑钠Sodium cefmetazole;头孢美唑钠|||Sodium cefmetazole
Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.
价 格:¥电议型 号:T1070产 地:中国大陆
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T10670Candesartan-d4;坎地沙坦 D4CV-11974 D4;坎地沙坦 D4|||CV-11974 D4
Candesartan D4 is the deuterium labeled Candesartan. Candesartan is an antagonist of angiotensin II receptor.
价 格:¥电议型 号:T10670产 地:中国大陆
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T1067Amphotericin B两性霉素BNSC 527017|||两性霉素B
Amphotericin B (NSC-527017) is a polyene antifungal agent with broad-spectrum activity against many fungal species. Amphotericin B irreversibly binds to ergosterol and disrupts the integrity of cell membranes, resulting in antifungal activity.
价 格:¥电议型 号:T1067产 地:中国大陆
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T10608BRD5648;化合物BRD5648(R)-BRD0705;(R)-BRD0705
BRD5648 ((R)-BRD0705) is an inactive (R)-enantiomer of BRD0705. BRD0705 is a GSK3α inhibitor (IC50: 66 nM; Kd: 4.8 μM) and can be used in acute myeloid leukemia (AML) studies.
价 格:¥电议型 号:T10608产 地:中国大陆
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T10606BRD0705;化合物BRD0705BRD0705
BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor (IC50: 66 nM; Kd: 4.8 μM). BRD0705 displays increased selectivity for GSK3α (8-fold) versus GSK3β (IC50: 515 nM).
价 格:¥电议型 号:T10606产 地:中国大陆
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T10590Zatolmilast;化合物BPN14770BPN14770;BPN14770
Zatolmilast (BPN14770) is an allosteric inhibitor of selective phosphodiesterase 4D (PDE4D; IC50s: 7.8 nM and 7.4 nM for PDE4D7 and PDE4D3).
价 格:¥电议型 号:T10590产 地:中国大陆
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T10570Fostemsavir Tris;化合物Fostemsavir TrisBMS-663068 Tris;BMS-663068 Tris
Fostemsavir Tris (BMS-663068 Tris) is the prodrug of BMS-626529,is a oral, safe and effective inhibitor of HIV-1 attachment. It inhibits human immunodeficiency virus type 1 (HIV-1) infection by binding to gp120 and interfering with the attachment of virus to CD4+ T-cells.
价 格:¥电议型 号:T10570产 地:中国大陆
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T10568BMS-470539 dihydrochloride;化合物 T10568BMS-470539 dihydrochloride
BMS-470539 dihydrochloride is a highly potent and selective agonist of the melanocortin-1 receptor (MC-1R; IC50: 120 nM; EC50: 28 nM) with anti-inflammatory properties. It does not activate MC-3R and is a very weak partial agonist at MC-4R and MC-5R.
价 格:¥电议型 号:T10568产 地:中国大陆
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T10536BI 703704;化合物 T10536BI 703704
BI 703704, a soluble guanylate cyclase (sGC) activator, inhibits the progression of diabetic nephropathy in the ZSF1 rat [1].
价 格:¥电议型 号:T10536产 地:中国大陆
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T10471BAY 60-2770;化合物 T10471BAY 60-2770
BAY 60-2770 is a selective and orally active soluble guanylyl cyclase (sGC) activator with antifibrotic effect. It increases the activity of sGC in a nitric oxide-independent manner.
价 格:¥电议型 号:T10471产 地:中国大陆
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T10395ATM-3507 trihydrochloride (1861449-70-8 free base);化合物 T10395ATM-3507 trihydrochloride;ATM-3507 trih
ATM-3507 trihydrochloride is a potent tropomyosin inhibitor (IC50s: 3.83-6.84 μM in human melanoma cell lines).
价 格:¥电议型 号:T10395产 地:中国大陆
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T10370ARN 077化合物 T10370URB913
ARN 077 is a selective N-acylethanolamine acid amidase (NAAA) inhibitor (IC50: 7 nM for human NAAA). ARN 077 significantly increases palmitoyl ethanolamine (PEA) levels within the CNS.
价 格:¥电议型 号:T10370产 地:中国大陆
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T10296Mavorixafor trihydrochloride;化合物 T10296AMD-070 trihydrochloride;AMD-070 trihydrochloride
Mavorixafor trihydrochloride is a selective and orally available CXCR4 antagonist (IC50: 13 nM against CXCR4 125I-SDF binding) and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs (IC50s: 1 and 9 nM).
价 格:¥电议型 号:T10296产 地:中国大陆
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T10290LAlpertine HCl;阿尔哌汀盐酸盐Win 31665 HCl|||Alpertine HCl(27076-46-6 Free base);Win 31665 HCl|||Alpertine H
Alpertine HCl is a small molecule compound with anti-neuropathic properties.
价 格:¥电议型 号:T10290L产 地:中国大陆
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T10270BAY 2416964;化合物BAY 2416964BAY 2416964
BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist(example 192, IC50: 341 nM). It has the potential for cancer treatment.
价 格:¥电议型 号:T10270产 地:中国大陆
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T10239Acolbifene;阿考比芬EM-652|||SCH 57068;阿考比芬|||EM-652|||SCH 57068
Acolbifene (SCH 57068) is a selective antagonist of estrogen receptors with IC50s of 2 nM and 0.4 nM for estradiol-induced transcriptional activity of ERα and ERβ. Acolbifene shows an anticarcinogenic property.
价 格:¥电议型 号:T10239产 地:中国大陆
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T10202A 1070722;化合物A 1070722A 1070722
A 1070722 is a potent and selective GSK-3 inhibitor, shows high affinity GSK-3α(Ki = 0.6 nM) and GSK-3β(Ki = 0.6 nM). It can penetrate the blood-brain barrier (BBB) and accumulates in brain regions, thus potential for PET radiotracer for the quantification of GSK-3 in brain.
价 格:¥电议型 号:T10202产 地:中国大陆
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T101705-HT7 agonist 1;化合物5-HT7 agonist 14-[4-[(2-chlorophenyl)methyl]-1-piperazinyl]-1H-indole|||4-[4-[(2-
5-HT7 agonist 1 (4-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]-1H-indole) is a selective agonist of 5-HT7 (IC50 = 222.93 nM). 5-HT7 agonist 1 can be used in studies about CNS disorders.
价 格:¥电议型 号:T10170产 地:中国大陆
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T0970Racanisodamine;消旋山莨菪碱Anisodamine|||7β-Hydroxyhyoscyamine|||Raceanisodamine;山莨菪碱|||Anisodamine|||7β-H
Racanisodamine (7β-Hydroxyhyoscyamine) is an anticholinergic and α1-adrenergic receptor antagonist used in the treatment of acute circulatory shock.
价 格:¥电议型 号:T0970产 地:中国大陆
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T0932Cefixime;头孢克肟FK-027|||Cefspan|||Cefiximum|||Cephoral|||FR-17027|||CL-284635;FK-027|||头孢克肟|||Cefspan|
Cefixime (FR-17027) is a broad-spectrum, third-generation cephalosporin antibiotic derived semisynthetically from the marine fungus Cephalosporium acremonium with antibacterial activity. As does penicillin, the beta-lactam antibiotic cefixime inhibits bacterial cell wall synthesis by disrupting peptidoglycan synthesis, resulting in a reduction in bacterial cell wall stability and bacterial cell lysis. Stable in the presence of a variety of beta-lactamases, this agent is more active against gram-
价 格:¥电议型 号:T0932产 地:中国大陆