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T19018K114；化合物 T19018K114
K114 binds tightly to amyloid fibrils (EC50: 20-30 nM). K114 is an efficient detector of semen-derived enhancer of virus infection (SEVI).
价 格：￥电议型 号：T19018产 地：中国大陆
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T17292ZK159222；化合物 T17292ZK159222
ZK159222 is an effective 1α,25-(OH)2D3 receptor (VDR) agonist. ZK159222 has a partial agonistic character.
价 格：￥电议型 号：T17292产 地：中国大陆
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T16944STK16-IN-1；化合物STK16-IN-1STK16-IN-1
STK16-IN-1 is an inhibitor of STK16 kinase (IC50: 295 nM).
价 格：￥电议型 号：T16944产 地：中国大陆
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T16547PK14105；化合物 T16547PK14105
PK14105 has been evaluated biologically as a potential radioligand for positron emission tomography (PET) studies targeting peripheral benzodiazepine binding sites (PBBS) receptors. When administered to rats with unilaterally lesioned striata, PK14105 was observed to quickly cross the blood-brain barrier, displaying significant radioactivity retention in the lesioned striatum, in contrast to the unlesioned striatum or cerebellar vermis. Additionally, PK14105 has the capability to inhibit recepto
价 格：￥电议型 号：T16547产 地：中国大陆
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T16450PDK1-IN-RS2；化合物 T16450PDK1-IN-RS2
PDK1-IN-RS2 inhibits the activation of the downstream kinases S6K1 by PDK1. PDK1-IN-RS2 is a mimic of the peptide docking motif (PIFtide) and is a substrate-selective PDK1 inhibitor (Kd: 9 μM).
价 格：￥电议型 号：T16450产 地：中国大陆
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T16367NVS-PAK1-1；化合物NVS-PAK1-1NVS-PAK1-1
NVS-PAK1-1 is an effective and selective allosteric PAK1 inhibitor (IC50: 5 nM).
价 格：￥电议型 号：T16367产 地：中国大陆
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T16078Mirk-IN-1化合物 T16078Dyrk1B/A-IN-1
Mirk-IN-1 is an effective inhibitor of Dyrk1B(Mirk kianse) and Dyrk1A (IC50: 68±48 nM and 22±8 nM respectively).
价 格：￥电议型 号：T16078产 地：中国大陆
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T15640K134；化合物 T15640OPC33509；OPC33509
K134 is an inhibitor of phosphodiesterase 3. The IC50s of K134 for PDE3A, PDE3B, PDE5, PDE2 and PDE4 are 0.1, 0.28, 12.1, >300 and >300 μM, respectively.
价 格：￥电议型 号：T15640产 地：中国大陆
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T15606JAK1-IN-4；化合物 T15606JAK1-IN-4
JAK1-IN-4 is a selective JAK1 inhibitor (IC50s: 85 nM, 12.8 μM and >30 μM for JAK1, JAK2, and JAK3, respectively). JAK1-IN-4 inhibits STAT3 phosphorylation in NCI-H 1975 cells (IC50, 227 nM).
价 格：￥电议型 号：T15606产 地：中国大陆
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T15559TBK1/IKKε-IN-2；化合物TBK1/IKKε-IN-2TBK1/IKKε-IN-2
TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε.
价 格：￥电议型 号：T15559产 地：中国大陆
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T15555IK1 inhibitor PA-6；化合物IK1 inhibitor PA-6IK1 inhibitor PA-6
IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouse KIR2.x currents).
价 格：￥电议型 号：T15555产 地：中国大陆
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T15426GSK180；化合物 T15426GSK180
GSK180 is a selective competitive inhibitor of kynurenine 3-monooxygenase (KMO; IC50: ~6 nM), an enzyme involved in tryptophan metabolism.
价 格：￥电议型 号：T15426产 地：中国大陆
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T15425GSK1702934A；化合物 T15425GSK1702934A
GSK1702934A is a selective TRPC3 agonist. It modulates cardiac contractility and f arrhythmogenesis by activation of TRPC3.
价 格：￥电议型 号：T15425产 地：中国大陆
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T15424GSK1379725A；化合物GSK1379725AGSK1379725A
GSK1379725A is a selective BPTF ligand (Kd = 2.8 μM).
价 格：￥电议型 号：T15424产 地：中国大陆
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T14990CDK12-IN-3；化合物 T14990CDK12-IN-3
CDK12-IN-3 is a selective CDK12 inhibitor (IC50: 491 nM in an enzymatic assay).
价 格：￥电议型 号：T14990产 地：中国大陆
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T14915CDK12-IN-E9；化合物 T14915CDK12-IN-E9
CDK12-IN-E9 is a potent and selective covalent CDK12 inhibitor and non-covalent CDK9 inhibitor while avoiding ABC transporter-mediated efflux. It has a weak binding ability to CDK7/CyclinH complex (IC50> 1 μM).
价 格：￥电议型 号：T14915产 地：中国大陆
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T14914Cdk1/2 Inhibitor III；Cdk1/2 抑制剂IIICdk1/2 Inhibitor III
Cdk1/2 Inhibitor III is a selective Cdk1/2 inhibitor with an IC50 value of 2.1 μM against CDK1/cyclin B.
价 格：￥电议型 号：T14914产 地：中国大陆
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T14364AZ-Dyrk1B-33；化合物T143643-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine；3-(2-Met
AZ-Dyrk1B-33 (3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine) is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.
价 格：￥电议型 号：T14364产 地：中国大陆
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T13744K 01-162；化合物 T13744K162；K162
K 01-162 binds and destabilizes AβO (β-amyloid), with an EC50 of 80 nM.
价 格：￥电议型 号：T13744产 地：中国大陆
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T13404ZK168281；化合物 T13404ZK168281
ZK168281 is a 25-carboxylic ester 1α,25(OH)2D3 analog and a pure antagonist of VDR (Kd of 0.1 nM). ZK168281 is an effective inhibitor of the coactivator (CoA) interaction of its receptor.
价 格：￥电议型 号：T13404产 地：中国大陆
