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T40581TIE-2/VEGFR-2 kinase-IN-2；TIE-2/VEGFR-2 kinase-IN-2TIE-2/VEGFR-2 kinase-IN-2
TIE-2/VEGFR-2 kinase-IN-2 is a powerful inhibitor of both VEGFR2 and Tie-2 kinases, displaying noteworthy pIC 50 values of 8.61 and 8.56, respectively. This compound acts as an anti-angiogenic agent, making it highly relevant for cancer research.
价 格：￥电议型 号：T40581产 地：中国大陆
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T40336IRE1α kinase-IN-6IRE1α kinase-IN-6IRE1α kinase-IN-6
IRE1α kinase-IN-6 is a potent IRE1α inhibitor with an IC 50 value of 4.4 nM.
价 格：￥电议型 号：T40336产 地：中国大陆
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T4026SU5408化合物VEGFR2 Kinase Inhibitor IVEGFR2 Kinase Inhibitor I
SU5408 (VEGFR2 Kinase Inhibitor I) is a potent, cell-permeable inhibitor of the VEGFR2 kinase.
价 格：￥电议型 号：T4026产 地：中国大陆
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T3989SMI-16a；化合物SMI-16aPIM1/2 Kinase Inhibitor VI；PIM1/2 Kinase Inhibitor VI
SMI-16a (PIM1/2 Kinase Inhibitor VI) , a cell-permeable thiazolidinedione compound, acts as an effective, ATP-competitive inhibitor against Pim-1/2 kinases (IC50: 150/20 nM) while exhibiting little or no activity against a panel of 57 other kinases (≤18% inhibition at 5 μM).
价 格：￥电议型 号：T3989产 地：中国大陆
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T39860Protein kinase inhibitors 1 hydrochloride；Protein kinase inhibitors 1 hydrochlorideProtein kinase in
Protein Kinase Inhibitors 1 Hydrochloride effectively inhibits HIPK2, demonstrating high potency with IC50 values of 136 nM for HIPK1 and 74 nM for HIPK2, alongside a dissociation constant (Kd) of 9.5 nM for HIPK2.
价 格：￥电议型 号：T39860产 地：中国大陆
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T39574RIP2 Kinase Inhibitor 4；RIP2 Kinase Inhibitor 4RIP2 Kinase Inhibitor 4
RIP2 Kinase Inhibitor 4 is a highly potent and selective RIPK2 PROTAC compound that efficiently degrades RIPK2 (with a pIC50 value of 8) and effectively inhibits the release of TNF-α.
价 格：￥电议型 号：T39574产 地：中国大陆
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T39482Casein Kinase inhibitor A86；Casein Kinase inhibitor A86Casein Kinase inhibitor A86；Casein Kinase inh
Casein Kinase inhibitor A86 is a highly effective and orally bioavailable inhibitor of casein kinase 1α (CK1α). Additionally, it displays inhibitory actions towards CDK7 (TFIIH) and CDK9 (P-TEFb). Furthermore, Casein Kinase inhibitor A86 demonstrates the ability to induce apoptosis in leukemia cells, portraying substantial anti-leukemic effects.
价 格：￥电议型 号：T39482产 地：中国大陆
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T39178Tyrosine Kinase Peptide 1；Tyrosine Kinase Peptide 1Tyrosine Kinase Peptide 1
Tyrosine Kinase Peptide 1 is a control substrate peptide for c-Src assay.
价 格：￥电议型 号：T39178产 地：中国大陆
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T38841IRE1α kinase-IN-2；IRE1α kinase-IN-2IRE1α kinase-IN-2；IRE1α kinase-IN-2
IRE1α kinase-IN-2 is a highly potent inhibitor of IRE1α kinase, demonstrating an EC50 of 0.82 μM. It effectively impedes IRE1α kinase autophosphorylation with an IC50 of 3.12 μM. Additionally, IRE1α kinase-IN-2 effectively inhibits the splicing of XBP1 mRNA in wild-type cell lines.
价 格：￥电议型 号：T38841产 地：中国大陆
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T38736Nattokinase；NattokinaseNattokinase
Nattokinase is a powerful fibrinolytic enzyme that effectively hydrolyzes fibrin and plasmin substrate, leading to the breakdown of blood clots. Its efficacy renders it valuable for cardiovascular disease studies.
价 格：￥电议型 号：T38736产 地：中国大陆
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T37248Pantothenate Kinase Inhibitor；Pantothenate Kinase InhibitorPantothenate Kinase Inhibitor
Pantothenate Kinase Inhibitor (PANKi) is a reversible inhibitor of pantothenate kinase (PanK; IC50s = 70, 92, and 25 nM for PanK1β, PanK2, and PanK3, respectively), the rate-limiting enzyme in the synthesis of coenzyme A .1It binds to the ATP-PanK3 complex with an apparent binding constant of 300 nM and exhibits mixed-type inhibition with respect to ATP and pantothenate. PANKi inhibits CoA biosynthesis in C3A cells (IC50= 0.9 μM) with no effect on cell viability when used at concentrations up to
价 格：￥电议型 号：T37248产 地：中国大陆
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T3722MK-1064；化合物MK1064Urokinase inhibitor 1|||MK 1064；Urokinase inhibitor 1|||MK 1064
MK-1064 (Urokinase inhibitor 1) is a selective orexin 2 receptor antagonist (2-SORA).
价 格：￥电议型 号：T3722产 地：中国大陆
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T37079VEGFR2 Kinase Inhibitor II；VEGFR2 Kinase Inhibitor IIVEGFR2 Kinase Inhibitor II
Vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR and FLK1) is a receptor tyrosine kinase that regulates angiogenesis, vascular development, and embryonic hematopoiesis in response to VEGF isoforms A, C, and D. VEGFR2 kinase inhibitor II is a reversible, cell-permeable inhibitor of VEGFR2´s kinase activity (IC50 = 70 nM). It less potently inhibits the platelet-derived growth factor receptor β (PDGFRβ; IC50 = 920 nM) and related receptor and non-receptor tyrosine kina
价 格：￥电议型 号：T37079产 地：中国大陆
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T36011p38 MAP Kinase Inhibitor IV；p38 MAPK Inhibitor IVp38 MAPK Inhibitor IV；p38 MAPK Inhibitor IV
p38 MAPK inhibitor IV is an ATP-competitive inhibitor of p38 MAP kinases with IC50 values of 0.13, 0.55, 5.47, and 8.63 μM for p38α, p38β, p38x, and p38δ, respectively, in vitro.[1] It also inhibits LPS-induced TNF-α and IL-1β cytokine production (IC50s = 22 and 44 nM, respectively) in human peripheral blood mononuclear cells.
价 格：￥电议型 号：T36011产 地：中国大陆
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T3593Src Inhibitor 1；化合物Src Inhibitor 1Src Kinase Inhibitor 1|||Src-l1；Src Kinase Inhibitor 1|||Src-l1
Src Inhibitor 1 (Src Kinase Inhibitor 1) is a potent and selective dual site Src tyrosine kinase inhibitor.
价 格：￥电议型 号：T3593产 地：中国大陆
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T35827Epsilon-V1-2；PKCε Inhibitor PeptidePKCε Inhibitor Peptide|||Protein Kinase C? Inhibitor Peptide|||?V
Protein kinase C (PKC ) is a calcium-independent, phospholipid- and diacylglycerol-dependent serine/threonine kinase involved in diverse signaling pathways, including those involved in neuronal signaling, cytoskeletal function, and inflammation.[1] PKC inhibitor peptide is a synthetic peptide corresponding to an amino acid sequence found in the amino terminal C2 domain of most mammalian forms of PKC .[2] It selectively and reversibly inhibits the translocation of PKC to intracellular membrane
价 格：￥电议型 号：T35827产 地：中国大陆
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T35536Tpl2 Kinase Inhibitor (hydrochloride)；Tpl2 Kinase Inhibitor (hydrochloride)Tpl2 Kinase Inhibitor (hy
Tpl2 kinase inhibitor is an inhibitor of tumor progression locus 2 (Tpl2; IC50= 0.05 μM).1It is selective for Tpl2 over MEK, p38 MAPK, Src, MK2, and PKC (IC50s = >40, 180, >400, 110, and >400 μM, respectively). Tpl2 kinase inhibitor inhibits LPS-induced TNF-α production in isolated human monocytes and whole blood (IC50s = 0.7 and 8.5 μM, respectively). It enhances differentiation induced by calcitriol in HL-60 and U937 leukemia cells when used at a concentration of 5 μM.2Tpl2 kinase inhibitor (5
价 格：￥电议型 号：T35536产 地：中国大陆
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T35526PI3-Kinase α Inhibitor 2 (hydrochloride)；PI3-Kinase α Inhibitor 2 (hydrochloride)PI3-Kinase α Inhibi
PI3-Kinase α Inhibitor 2 (hydrochloride) is a PI3-Kinase α inhibitor.
价 格：￥电议型 号：T35526产 地：中国大陆
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T35525PI3-Kinase α Inhibitor 2；PI3-Kinase α Inhibitor 2PI3-Kinase α Inhibitor 2；PI3-Kinase α Inhibitor 2
Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of the 3´ hydroxyl position of PIs to produce the second messengers PtdIns-(3,4)-P2 and PtdIns-(3,4,5)-P3. PI3Kα, β, and δ are class 1A enzymes composed of p110 and p85 subunits, whereas PI3Kγ is a class 1B PI3K composed of a p110 catalytic subunit and a p101 or p84 regulatory subunit. PI3Kα inhibitor 2 is a selective inhibitor of PI3Kα with IC50 values of 2, 16, 660, and 220 nM for the α, β, γ, and 2Cβ isoforms, respective
价 格：￥电议型 号：T35525产 地：中国大陆
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T3080Pyridone 6；吡啶酮6Janus-Associated Kinase Inhibitor I|||JAK Inhibitor|||CMP 6|||JAK Inhibitor I；Janus-A
Pyridone 6 (JAK Inhibitor)(CMP 6) is a potent and selective inhibitor of JAK1 (IC50=15 nM, murine JAK1), JAK2 (IC50=1 nM), JAK3 (Ki=5 nM), and Tyk2 (IC50=1 nM); displaying significantly weaker affinities (130 nM to 10 mM) for other protein tyrosine kinases.
价 格：￥电议型 号：T3080产 地：中国大陆
