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T6352(-)-Dizocilpine maleate(-)-MK 801 (Maleate);C13737;(-)-MK 801 Maleate;(-)-MK 801马来酸
MK-801 is a potent, selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes.
价 格:¥电议型 号:T6352产 地:中国大陆
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T6351MGCD-265 analogGlesatinib;MGCD-265
MGCD-265-analog (structurally related to MGCD-265) is an orally bioavailable multitargeted tyrosine kinase inhibitor with potential antineoplastic activity with IC50 of 29 nM and 10 nM for c-Met and VEGFR2, respectively.
价 格:¥电议型 号:T6351产 地:中国大陆
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T6350CHIR-124CHIR 124;CHIR124
CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4.
价 格:¥电议型 号:T6350产 地:中国大陆
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T5635CH7057288
CH7057288 is an effective and selective TRK inhibitor with an IC50 value of 1.1 nM, 7.8 nM and 5.1 nM for TRKA, TRKB and TRKC, respectively.
价 格:¥电议型 号:T5635产 地:中国大陆
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T5392TP0463518
TP-0463518 is a highly potent HIF prolyl hydroxylase (PHD) inhibitor (IC50s: 13 nM and 18 nM for human and rat PHD2, respectively).
价 格:¥电议型 号:T5392产 地:中国大陆
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T4635RalinepagAPD811
Ralinepag is a potent, orally bioavailable and non-prostanoid prostacyclin (IP) receptor agonist, with EC50s of 8.5 nM, 530 nM and 850 nM for human and rat IP receptor and human DP1 receptor, respectively.
价 格:¥电议型 号:T4635产 地:中国大陆
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T4265AZD4635HTL1071
AZD4635 is a new-type adenosine 2A receptor (A2AR) inhibitor(Ki=1.7 nM).
价 格:¥电议型 号:T4265产 地:中国大陆
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T39635Obafistat
Obafistat is a potent aldo-keto reductase AKR1C3 inhibitor with an IC 50 of 1.2 nM for human AKR1C3 (patent WO2017202817A1, example 4) [1] .
价 格:¥电议型 号:T39635产 地:中国大陆
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T3635IQ 1IQ-1;IQ1
Maintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells; enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation. Upregulates expression of Oct4 and Sox2 transcription factors. Binds to serine/threonin
价 格:¥电议型 号:T3635产 地:中国大陆
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T3119JNJ-63533054JNJ63533054;JNJ 63533054
JNJ-63533054 is a potent and selective agonist of hGPR139 with an EC50 = 16 nM.
价 格:¥电议型 号:T3119产 地:中国大陆
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T2S16353-Isomangostin
3-Isomangostin is an acetylcholinesterase selective inhibitor and a potent human aldose reductase inhibitor with an IC50 of 3.48 uM. 3-Isomangostin has free radical scavenging activity and inhibits MutT homolog 1 (MTH1) with an IC50 of 52 nM. It shows ant
价 格:¥电议型 号:T2S1635产 地:中国大陆
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T28804Slingshot inhibitor D3JHN76359
Slingshot inhibitor D3 is a potent inhibitor of the Protein Phosphatase Slingshot.
价 格:¥电议型 号:T28804产 地:中国大陆
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T27635IsoxepacOlopatadine USP Related Compound C
Isoxepac is a non-steroidal anti-antiphlogistic agent and analgesic.
价 格:¥电议型 号:T27635产 地:中国大陆
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T26357Pitstop 2
Pitstop 2 is a inhibitor of clathrin, and inhibits clathrin-mediated endocytosis (CME) by associating with the terminal domain of clathrin. It has the potential for anti-cancer research.
价 格:¥电议型 号:T26357产 地:中国大陆
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T2631WAY-100635 Maleate
WAY-100635 is a specific and effective 5-HT receptor antagonist (IC50=0.95 nM).
价 格:¥电议型 号:T2631产 地:中国大陆
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T25635LateritinBassiatin
Lateritin is An Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor and a platelet aggregation inhibitor from the mycelial cake of Gibberella lateritium. Bassiatin is the (3S,6R) isomer.
价 格:¥电议型 号:T25635产 地:中国大陆
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T2514LinifanibRG3635;ABT-869;AL-39324
Linifanib (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and PDGFRβ (IC50: 66 nM). Linifanib may exhibit potent antiproliferative and apoptotic effects on tumor cells wh
价 格:¥电议型 号:T2514产 地:中国大陆
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T21635PD184161
PD184161 is a novel, orally-active MEK inhibitor. PD184161 inhibited MEK activity (IC50 = 10-100 nM) in a time- and concentration-dependent manner[1].
价 格:¥电议型 号:T21635产 地:中国大陆
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T16359NU6140
NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM). It shows 10- to 36-fold selectivity over other CDKs. NU6140 also effectively inhibits Aurora A and Aurora B (IC50s: 67 and 35 nM, respectively). It also enhances the apoptotic effect and ha
价 格:¥电议型 号:T16359产 地:中国大陆
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T16355NSC781406
NSC781406 is a highly effective inhibitor of PI3K and mTOR (IC50: 2 nM for PI3Kα).
价 格:¥电议型 号:T16355产 地:中国大陆