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T16359NU6140NU6140
NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM). It shows 10- to 36-fold selectivity over other CDKs. NU6140 also effectively inhibits Aurora A and Aurora B (IC50s: 67 and 35 nM, respectively). It also enhances the apoptotic effect and ha
价 格:¥电议型 号:T16359产 地:美洲
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T16700QC6352QC6352
QC6352 is a selective and effective KDM4C inhibitor (IC50: 35 nM).
价 格:¥电议型 号:T16700产 地:美洲
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T2631WAY-100635 MaleateWAY-100635 Maleate
WAY-100635 is a specific and effective 5-HT receptor antagonist (IC50=0.95 nM).
价 格:¥电议型 号:T2631产 地:美洲
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T4635RalinepagRalinepag,APD811,
Ralinepag is a potent, orally bioavailable and non-prostanoid prostacyclin (IP) receptor agonist, with EC50s of 8.5 nM, 530 nM and 850 nM for human and rat IP receptor and human DP1 receptor, respectively.
价 格:¥电议型 号:T4635产 地:美洲
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T5392TP0463518TP0463518
TP-0463518 is a highly potent HIF prolyl hydroxylase (PHD) inhibitor (IC50s: 13 nM and 18 nM for human and rat PHD2, respectively).
价 格:¥电议型 号:T5392产 地:美洲
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T5635CH7057288CH7057288
CH7057288 is an effective and selective TRK inhibitor with an IC50 value of 1.1 nM, 7.8 nM and 5.1 nM for TRKA, TRKB and TRKC, respectively.
价 格:¥电议型 号:T5635产 地:美洲
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T8635CI 75300;化合物CI 75300CI 75300
CI 75300 targets the P2X purinoceptor 7 (human).
价 格:¥电议型 号:T8635产 地:中国大陆
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T82994Anzurstobart;化合物 AnzurstobartBMS-986351|||CC-95251;BMS-986351|||CC-95251
Anzurstobart (CC-95251; BMS-986351), a fully human monoclonal anti-SIRPα antibody with high affinity, inhibits CD47-SIRPα interaction. It potentiates macrophage-mediated phagocytosis of DLBCL cell lines in co-culture assays with Rituximab and shows promise in solid and hematologic malignancy research [1].
价 格:¥电议型 号:T82994产 地:中国大陆
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T82635Cy-FBP/SBPase-IN-1;化合物 Cy-FBP/SBPase-IN-1Cy-FBP/SBPase-IN-1
Cy-FBP/SBPase-IN-1 (compound S5) serves as an inhibitor of the key regulatory enzyme Cy-FBP/SBPase in cyanobacterial photosynthesis, impeding the Calvin cycle and photosystem, thereby reducing photosynthetic efficiency. It effectively suppresses the proliferation of cyanobacteria, including Synechocystis sp. PCC6803, while demonstrating a safe profile in human-derived cell lines and zebrafish models [1].
价 格:¥电议型 号:T82635产 地:中国大陆
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T82434Etiroxate;化合物 EtiroxateCG-635;CG-635
Etiroxate (CG-635) is a lipid-lowering agent utilized in hyperlipoproteinemia studies [1].
价 格:¥电议型 号:T82434产 地:中国大陆
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T82012Janelia Fluor? 635, SE;化合物 Janelia Fluor? 635, SEJF635, NHS|||JF635, SE;JF635, NHS|||JF635, SE
Janelia Fluor? 635, SE (JF635, SE) is a red fluorogenic dye featuring an NHS ester for conjugation with primary amine groups, suitable for live cell imaging [1].
价 格:¥电议型 号:T82012产 地:中国大陆
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T81635Nurr1 agonist 5;化合物 Nurr1 agonist 5Nurr1 agonist 5
Compound 5o, a Nurr1 agonist, exhibits neuroprotective properties as a transcription factor Nurr1 agonist, possessing a dissociation constant (Kd) of 0.5 μM and a half-maximal effective concentration (EC50) of 3 μM [1].
价 格:¥电议型 号:T81635产 地:中国大陆
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T80635Gentisuric acid;化合物 Gentisuric acidGentisuric acid
Gentisuric acid, an Aspirin metabolite and a substrate of α-amidating monooxygenase (PAM), mitigates DNA damage induced by Mitomycin C. [1] [2]
价 格:¥电议型 号:T80635产 地:中国大陆
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T79635LYP-IN-4;化合物 LYP-IN-4LYP-IN-4
LYP-IN-4 (compound D14), a reversible and selective lymphotyrosine phosphatase (LYP) inhibitor (Ki=1.34 μM, IC50=3.52μM), regulates TCR signaling, increases PD-1/PD-L1 expression, and strengthens anti-tumor immunity. It also stimulates T cell activation, impedes M2 macrophage polarization, and suppresses tumor progression in MC38 isogenic mouse models.
价 格:¥电议型 号:T79635产 地:中国大陆
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T77635LSD1-IN-27;LSD1抑制剂27LSD1-IN-27
LSD1-IN-27 is a potent LSD1 inhibitor with an IC50 value of 13 nM.LSD1-IN-27 inhibited the stemness and migration of gastric cancer cells.LSD1-IN-27 inhibited the expression of PD-L1 in BGC-823 and MFC cells.LSD1-IN-27 potentiated the T-cell immune response against gastric cancer.
价 格:¥电议型 号:T77635产 地:中国大陆
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T77367Urelumab;乌瑞芦单抗BMS-663513|||BMS-66513;BMS-663513|||BMS-66513
Urelumab(BMS-66513) is a humanized IgG4 monoclonal antibody, often used as a CD137 agonist.Urelumab has potential antitumor activity, potentiating tumor cell killing by T-cells and natural killer cells, and enhancing the cytotoxicity of Rituximab.Urelumab has been used in the study of solid tumor-related diseases such as diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL). Urelumab can be used to study diseases associated with solid tumors such as diffuse large B-cell lymphoma (DL
价 格:¥电议型 号:T77367产 地:中国大陆
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T76635(Trp7,β-Ala8)-Neurokinin A (4-10);化合物 (Trp7,β-Ala8)-Neurokinin A (4-10)(Trp7,β-Ala8)-Neurokinin A (4
(Trp7,β-Ala8)-Neurokinin A (4-10) is a potent neurokinin-3 (NK3) antagonist [1] .
价 格:¥电议型 号:T76635产 地:中国大陆
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T7635LRaclopride tartrate;化合物 T7635LFLA 870|||FLA-870|||FLA870;FLA 870|||FLA-870|||FLA870
Raclopride is a selective antagonist on D2 dopamine receptor ( D2 Ki: 1.8 nm, D3 Ki: 3.5 nm, D4 Ki: 2400, D1 Ki: 18000 nM).
价 格:¥电议型 号:T7635L产 地:中国大陆
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T76359[Nle13]-Motilin;化合物 [Nle13]-Motilin[Nle13]-Motilin
[Nle13]-Motilin, a motilin analogue, is a motilin receptor agonist [1] [2] .
价 格:¥电议型 号:T76359产 地:中国大陆
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T76358Neuropeptide Y (1-24) (human);化合物 Neuropeptide Y (1-24) (human)Neuropeptide Y (1-24) (human)
Neuropeptide Y (1-24) (human) is a neuropeptide that inhibits the electrically stimulated twitch response in rat vas deferens and activates neurons in the rat CA3 region of the dorsal hippocampus in vivo following N-methyl-D-aspartate (NMDA) induction [1] [2].
价 格:¥电议型 号:T76358产 地:中国大陆