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T6260AMG-208AMG 208;AMG208
AMG 208 is a highly selective c-Met inhibitor with IC50 of 9 nM. Phase 1.
价 格:¥电议型 号:T6260产 地:中国大陆
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T5479AMG 333AMG-333
AMG 333 is TRPM8 antagonist with an IC50 of 13 nM,a Clinical Candidate for the Treatment of Migraine.
价 格:¥电议型 号:T5479产 地:中国大陆
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T4411DAMGO TFA (78123-71-4(Free base))
Potent, selective agonist of Mu-opioid receptor. Antinociceptive. Stimulates calcium-activated adenylyl cyclases related cAMP production. Expresses chemokines and chemokine receptors through TGF-beta1. Increases food intake of rats.
价 格:¥电议型 号:T4411产 地:中国大陆
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T4351DAMGODagol;DAGO;RX-783006
DAMGO is an opioid receptor agonist with the ability to affect the locomotive activity in rodents. Possible analgesic agent due to μ-opiod receptor interaction.
价 格:¥电议型 号:T4351产 地:中国大陆
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T3209AMG-337AMG337;AMG 337
AMG-337 is an effective and highly specific ATP-competitive MET kinase inhibitor. In enzymatic assays, AMG-337 inhibits MET kinase activity (IC50: < 5 nM).
价 格:¥电议型 号:T3209产 地:中国大陆
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T2406Cinacalcet hydrochloride盐酸西那卡塞;Cinacalcet HCl;Cinacalcet;AMG-073 hydrochloride;AMG-073 HCl
Cinacalcet hydrochloride is a naphthalene derivative and CALCIMIMETIC AGENT that increases the sensitivity of PARATHYROID GLAND calcium-sensing receptors to serum calcium. This action reduces parathyroid hormone secretion and decreases serum calcium in th
价 格:¥电议型 号:T2406产 地:中国大陆
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T2288MotesanibAMG 706;莫特塞尼;莫替沙尼
Motesanib is an orally bioavailable receptor tyrosine kinase inhibitor with potential antineoplastic activity. AMG 706 selectively targets and inhibits vascular endothelial growth factor (VEGFR), platelet-derived growth factor (PDGFR), Kit, and Ret recept
价 格:¥电议型 号:T2288产 地:中国大陆
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T22258Sotorasib racemateAMG-510 racemate
AMG-510 racemate is a racemic of AMG-510 which is a potent inhibitor of KRAS G12C covalent, and leading to potential antineoplastic activity.
价 格:¥电议型 号:T22258产 地:中国大陆
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T14214AMG 511
AMG 511 is a potent and orally available pan inhibitor of class I PI3Ks(Kis of 4 nM, 6 nM, 2 nM and 1 nM for PI3Kα, β, δ and γ, respectively). It exhibits anti-tumor activity in mouse glioblastoma xenograft model[1]. AMG 511 significantly suppresses PI3K
价 格:¥电议型 号:T14214产 地:中国大陆
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T11762LKira8AMG-18
Kira8 is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity (IC50: 5.9 nM).
价 格:¥电议型 号:T11762L产 地:中国大陆
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T10300AMG2850
AMG2850 is a potent, orally bioavailable, and selective antagonist of transient receptor potential melastatin 8 (TRPM8).
价 格:¥电议型 号:T10300产 地:中国大陆
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T10297LAMG 487
AMG 487 is a potent and selective antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively.
价 格:¥电议型 号:T10297L产 地:中国大陆
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T10297AMG 487 (S-enantiomer)AMG 487 (S-enantiomer)
AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an CXCR3 antagonist.
价 格:¥电议型 号:T10297产 地:美洲
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T10297LAMG 487AMG 487
AMG 487 is an orally active and selective antagonist of CXC chemokine receptor 3 (CXCR3). It inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively.
价 格:¥电议型 号:T10297L产 地:美洲
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T10299AMG PERK 44AMG PERK 44
AMG PERK 44 is an orally active and selective PERK inhibitor (IC50: 6 nM) and induces autophagy. It has 1000-fold and 160-fold selectivity over GCN2 (IC50: 7300 nM) and B-Raf (IC50 >1000 nM), respectively.
价 格:¥电议型 号:T10299产 地:美洲
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T11762LKira8Kira8,AMG-18,
Kira8 is a mono-selective IRE1α inhibitor. That allosterically attenuates IRE1α RNase activity (IC50: 5.9 nM).
价 格:¥电议型 号:T11762L产 地:美洲
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T14217AMG 579AMG 579
AMG 579 is a phosphodiesterase 10A (PDE10A) inhibitor (IC50: 0.1 nM).
价 格:¥电议型 号:T14217产 地:美洲
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T2288MotesanibMotesanib,AMG 706,
Motesanib is an orally bioavailable receptor tyrosine kinase inhibitor with potential antineoplastic activity. AMG 706 selectively targets and inhibits vascular endothelial growth factor (VEGFR), platelet-derived growth factor (PDGFR), Kit, and Ret recept
价 格:¥电议型 号:T2288产 地:美洲
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T2406Cinacalcet hydrochlorideCinacalcet hydrochloride,Cinacalcet,AMG-073 hydrochloride
Cinacalcet hydrochloride is a naphthalene derivative and CALCIMIMETIC AGENT that increases the sensitivity of PARATHYROID GLAND calcium-sensing receptors to serum calcium. This action reduces parathyroid hormone secretion and decreases serum calcium in th
价 格:¥电议型 号:T2406产 地:美洲