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T5479AMG-333AMG-333
AMG 333 is TRPM8 antagonist with an IC50 of 13 nM,a Clinical Candidate for the Treatment of Migraine.
价 格:¥电议型 号:T5479产 地:美洲
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T6260AMG-208AMG-208,AMG208,AMG 208
AMG 208 is a highly selective c-Met inhibitor with IC50 of 9 nM. Phase 1.
价 格:¥电议型 号:T6260产 地:美洲
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T6380AMG-900AMG-900,AMG900,AMG 900
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM. It is >10-fold selective for Aurora kinases than p38α, Tyk2, JNK2, Met and Tie2. Phase 1.
价 格:¥电议型 号:T6380产 地:美洲
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T6384Ammonium GlycyrrhizinateAmmonium Glycyrrhizinate,AMGZ,Glycyram
Ammonium Glycyrrhizinate inhibits the cytopathology and growth of several unrelated DNA/RNA viruses.
价 格:¥电议型 号:T6384产 地:美洲
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T8780AMG131;化合物INT-131INT-131|||AMG-131|||CHS 131;INT-131|||AMG-131|||CHS 131
AMG131 (CHS 131) , is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used for the treatment of type 2 diabetes mellitus (non-insulin dependent diabetes)
价 格:¥电议型 号:T8780产 地:中国大陆
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T8684Sotorasib;化合物AMG-510AMG-510;AMG-510
Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C. Sotorasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Sotorasib exhibits inhibitory activity against KRAS G12C mutant tumors.
价 格:¥电议型 号:T8684产 地:中国大陆
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T8409SYN1143;化合物AMG-1RON-IN-1|||AMG-1;RON-IN-1|||AMG-1
SYN1143 (AMG-1) is a potent inhibitor of human RON and c-Met.In vitro kinase assays showed that compound I is a potent inhibitor of human RON and c-Met with IC50s of 9 and 4 nmol/L, respectively.
价 格:¥电议型 号:T8409产 地:中国大陆
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T8403Cinacalcet;西那卡塞AMG 073;西那卡塞|||AMG 073
Cinacalcet (AMG 073) is an orally active, allosteric Ca receptor (CaR) agonist, treatment of cardiovascular disease .
价 格:¥电议型 号:T8403产 地:中国大陆
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T83693Magainin 2 TFA;化合物 Magainin 2 TFAMG2;MG2
Magainin 2, a cationic peptide derived from the African clawed frog (X. laevis) skin, exhibits host defense and antimicrobial properties. This compound effectively inhibits a range of pathogens, including E. coli, K. pneumoniae, S. epidermidis, S. aureus bacteria, and C. albicans fungus, with minimum inhibitory concentrations (MICs) of 5, 10, 10, 50, and 80 ?g/ml, respectively. Additionally, at a concentration of 20 ?M, Magainin 2 significantly reduces the germination and tube elongation in kiwi
价 格:¥电议型 号:T83693产 地:中国大陆
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T82501Efavaleukin alfa;化合物 Efavaleukin alfaAMG592;AMG592
Efavaleukin alfa (AMG592) is a human monoclonal antibody comprising the IGHG1 Fc fragment fused to interleukin-2 (IL-2). It is typically expressed in Chinese Hamster Ovary (CHO) cells [1].
价 格:¥电议型 号:T82501产 地:中国大陆
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T81256Rozibafusp alfa;化合物 Rozibafusp alfaAMG-570;AMG-570
Rozibafusp alfa is an IgG2-κ antibody that targets ICOSLG, combined with a TNFSF13B fusion protein [1].
价 格:¥电议型 号:T81256产 地:中国大陆
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T81049Tamgiblimab;化合物 TamgiblimabIBI939;IBI939
Tamgiblimab (IBI939) is a fully human monoclonal antibody that targets the T-cell immunoreceptor with immunoglobulin and ITIM domains (TIGIT), exhibiting anticancer properties [1].
价 格:¥电议型 号:T81049产 地:中国大陆
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T80581Plutavimab;化合物 PlutavimabCOVI-AMG|||STI-2020;COVI-AMG|||STI-2020
Plutavimab is a humanized IgG1-κ monoclonal antibody targeting the receptor binding domain (RBD) of the SARS-CoV-2 spike (S) glycoprotein [1] [2].
价 格:¥电议型 号:T80581产 地:中国大陆
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T78333Rocatinlimab;化合物 RocatinlimabAMG 451|||KHK4083;AMG 451|||KHK4083
Rocatinlimab (AMG 451) (KHK4083) is a fully human, non-fucosylated IgG1 anti-OX40 monoclonal antibody indicated for atopic dermatitis (AD) research [1].
价 格:¥电议型 号:T78333产 地:中国大陆
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T77491Prezalumab;普瑞鲁单抗AMG 557;AMG 557
Prezalumab (AMG 557) is a human IgG2 monoclonal antibody against ICOSL and BAFF. Prezalumab can be used to study sjogren´s syndrome cutaneous lupus erythematosus, psoriasis, systemic lupus erythematosus arthritis and systemic lupus erythematosus (SLE).
价 格:¥电议型 号:T77491产 地:中国大陆
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T77359Tezepelumab;替西伐单抗Tezepelumab-ekko|||MEDI 19929|||AMG 157;Tezepelumab-ekko|||MEDI 19929|||AMG 157
Tezepelumab (AMG 157) is a humanized monoclonal antibody (IgG2λ) targeting TSLP that prevents TSLP from interacting with its heterodimer receptor. Tezepelumab can be used to study advanced asthma disease.
价 格:¥电议型 号:T77359产 地:中国大陆
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T76892Ordesekimab;奥司奇单抗AMG 714|||PRV-015;AMG 714|||PRV-015
Ordesekimab (AMG 714) is a human IgG1 κ-anti-IL-15 (Interleukin Related) monoclonal antibody. Ordesekimab binds competitively to IL-15, inhibiting the interaction of IL-15 with the common gamma chain of the IL-2Rβ and IL-15 receptor complex, but not with the IL-15Rα chain. Ordesekimab can be used to study non-reactive celiac disease (NRCD).
价 格:¥电议型 号:T76892产 地:中国大陆
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T76874Erenumab;厄瑞努单抗AMG-334;AMG-334
Erenumab is a whole-human monoclonal antibody. Erenumab inhibits calcitonin gene-related peptide (CGRP) receptors. Erenumab can be used to prevent migraine attacks.
价 格:¥电议型 号:T76874产 地:中国大陆
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T76810Ganitumab;加尼妥单抗AMG 479;AMG 479
Ganitumab (AMG 479) is a highly potent monoclonal antibody to type 1 insulin-like growth factor receptor (IGF1R). Ganitumab is recognized to bind to IGF1R at low concentration with KD value of 0.22 nM. Ganitumab can inhibit the interaction of IGF1R with IGF1 and IGF2 in mice. Ganitumab can be used to study cancer.
价 格:¥电议型 号:T76810产 地:中国大陆
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T76796Patritumab;帕曲妥单抗U3-1287|||AMG-888;U3-1287|||AMG-888
Patritumab (U3-1287) is an anti-HER3 monoclonal antibody with potential antitumor activity and inhibits phosphorylation of EGFR, HER2, HER3, ERK, and AKT.Patritumab promotes apoptosis and inhibits proliferation in non-small cell lung cancer.
价 格:¥电议型 号:T76796产 地:中国大陆