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T7155JH-II-127HEK293,JHII127,3T3 cells,Inhibitor,LRRK2-G2019S,Ser935,Leucine-rich repeat kinase 2,LRRK2,p
JH-II-127 is an orally inhibitor of leucine-rich repeat kinase 2 (LRRK2). It inhibits WT LRRK2, G2019S LRRK2 and A2016T LRRK2 (IC50s = 6.6, 2.2, and 47.7 nM, respectively),
价 格：￥电议型 号：T7155产 地：中国大陆
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T7729PF-06454589Inhibitor,G2019S LRRK2,inhibit,LRRK2,parkinson’s disease,PF06454589,PF 06454589,PF-064545
PF-06454589 is a potent inhibitor of LRRK2.
价 格：￥电议型 号：T7729产 地：中国大陆
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T8956BC-?1258LRR,F-box,inhibit,repeat,BC-?1258,BC ?1258,FBXL2,Apoptosis,tumor,Inhibitor,BC?1258
BC-1258 is a unique small molecule F-box/LRR-repeat protein 2 (FBXL2) activator.
价 格：￥电议型 号：T8956产 地：中国大陆
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T9287HydroxychloroquineParasite,Toll-like Receptor (TLR),SARS-CoV,Inhibitor,SARS coronavirus,Autophagy,Hy
Hydroxychloroquine (HCQ) is an alkalinizing lysosomatropic drug that acts by inducing apoptosis of renal cancer cells in vitro and inhibiting TLR7/9. It is a medication used to prevent and treat malaria, and it´s also being studied as an experimental treatment for COVID-19.
价 格：￥电议型 号：T9287产 地：中国大陆
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T7860SM-324405Inhibitor,Toll-like Receptor (TLR),low toxicity,TLR7,SM-324405,cytokine,diseases,immunother
SM 324405 is an agonist of TLR7.
价 格：￥电议型 号：T7860产 地：中国大陆
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T6964ResiquimodHepatitis C virus,R-848,S-28463,R 848,S 28463,Toll-like Receptor (TLR),Inhibitor,Resiquimo
Resiquimod is an imidazoquinoline amine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effect through the TLR signaling pathway by binding to and activating TLR7 and 8 mainly on dendritic cells, macrophages, and B-lymphocytes. This induces the nuclear translocation of the transcription activator NF-kB as well as activation of other transcription factors. This may lead to an increase in mRNA levels and subsequent production of cytokin
价 格：￥电议型 号：T6964产 地：中国大陆
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T7302CU-CPT9binhibit,Toll-like Receptor (TLR),CU-CPT9b,Inhibitor,CUCPT9b,CU CPT9b
CU-CPT9b is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM). It inhibits activation of NF- B induced by the TLR8 agonist R-848 in TLR8-overexpressing HEK-Blue cells with an IC50 value of 0.7 nM.
价 格：￥电议型 号：T7302产 地：中国大陆
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T7347CU-CPT-8mCU CPT 8m,inhibit,Toll-like Receptor (TLR),CUCPT8m,Inhibitor
CU-CPT-8m is an toll-like receptor 8 (TLR8) antagonist (IC50 : 67 nM)
价 格：￥电议型 号：T7347产 地：中国大陆
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T71254-Butylresorcinolinhibit,Tyrosinase,4Butylresorcinol,4 Butylresorcinol,4-Butylresorcinol,Inhibitor
4-Butylresorcinol is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.
价 格：￥电议型 号：T7125产 地：中国大陆
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T7033RosmanolRosmanol,Inhibitor,inhibit
Rosmanol has antioxidant activity, it can activate the antioxidant response element. Rosmanol has biphasic modulation of GABAA receptors, demonstrates CNS activity in mouse models of antinociception, antidepressant and anxiolysis. Rosmanol potently induces apoptosis through both the mitochondrial apoptotic pathway and death receptor pathway in human colon adenocarcinoma COLO 205 cells. Rosmanol has anti-inflammatory activity, it potently inhibits lipopolysaccharide-induced iNOS and COX-2 express
价 格：￥电议型 号：T7033产 地：中国大陆
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T34374RO5203648 HClRO5203648 HCl,RO-5203648 HCl
RO5203648 HCl is a partial agonist of trace amine-related receptor 1 (TAAR1) with antipsychotic and antidepressant-like activities. RO5203648 HCl can be used in studies about neuropsychiatric therapeutics.
价 格：￥电议型 号：T34374产 地：中国大陆
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T7573LTFLLR-NH2 2TFA(197794-83-5(free base))TFLLR NH2 2TFA(197794 83 5(free base)),TFLLR-NH-2 2TFA(197794-
TFLLR-NH2(2TFA) is an agonist of PAR1 (EC50 :1.9 μM).
价 格：￥电议型 号：T7573L产 地：中国大陆
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T6898MotolimodMotolimod,inhibit,VTX378,VTX 378,Inhibitor,Toll-like Receptor (TLR),VTX 2337,VTX2337
Motolimod (VTX-2337) is an effective and specific Toll-like receptor (TLR) 8 agonist (EC50: 100 nM), > 50-fold selectivity over TLR7.
价 格：￥电议型 号：T6898产 地：中国大陆
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T6591Nodinitib-1Nodinitib1,CID1088438,Inhibitor,NOD-like Receptor (NLR),Nodinitib 1,ML-130,ML 130,Nodinit
Nodinitib-1 is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.
价 格：￥电议型 号：T6591产 地：中国大陆
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TN2008OkaninToll-like Receptor (TLR),Nuclear factor-κB,NF-κB,Inhibitor,Nuclear factor-kappaB,Okanin,inhibi
Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect.
价 格：￥电议型 号：TN2008产 地：中国大陆
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T8841IMT1NDUFB8,chain,POLRMT,DNA/RNA Synthesis,Inhibitor,OXPHOS,Mitochondrial Metabolism,citric,IMT-1,deo
Anticancer.
价 格：￥电议型 号：T8841产 地：中国大陆
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T9570Enpatoraninhibit,M5049,Inhibitor,Toll-like Receptor (TLR),M-5049,autoimmunity,M 5049,TLR7/8,selectiv
Enpatoran is an inhibitor of TLR7(IC50 = 11.1 nM) and TLR8(IC50 = 24.1 nM). Enpatoran was found to be inactive against TLR3, TLR4, and TLR9 in vitro and in vivo.
价 格：￥电议型 号：T9570产 地：中国大陆
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T7672MD2-TLR4-IN-1inhibit,Toll-like Receptor (TLR),MD2 TLR4 IN 1,MD2TLR4IN1,MD-2-TLR4-IN-1,Inhibitor
MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex inhibitor.
价 格：￥电议型 号：T7672产 地：中国大陆
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T8828CP 424174CP424174,IL-1β,NLRP3,Inhibitor,CP 424174,CP-424174,Inflammasome,inhibit,NOD-like Receptor (
CP 424174 is an inhibitor of IL-1β post-translational processing with IC50 of 210 nM. Inhibits the formation of mature IL-1β. Indirectly inhibits NLRP3. Active in vivo and orally bioavailable.
价 格：￥电议型 号：T8828产 地：中国大陆
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T6S1302CarnosolRibosomal S6 Kinase (RSK),Keap1-Nrf2,Endogenous Metabolite,S6K,inhibit,Carnosol,Inhibitor
Carnosol has anti-oxidative, anti-inflammatory, antiproliferative and apoptosis inducing properties. Carnosol enhances the sensitivity of chemoresistant cancer cells to chemotherapeutic agents. 3. Carnosol may as a novel agonist of TRPA1 with an EC5 value of 12.46 μM.
价 格：￥电议型 号：T6S1302产 地：中国大陆
