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T82703CMKLR1 antagonist 1;化合物 CMKLR1 antagonist 1CMKLR1 antagonist 1
CMKLR1 antagonist 1 (compound S-26d) is a potent, orally active antagonist of the chemokine-like receptor 1 (CMKLR1), exhibiting a pIC50 of 7.44 in hCMKLR1-transfected CHO cells. It is applicable in the research of psoriasis and metabolic diseases [1].
价 格:¥电议型 号:T82703产 地:中国大陆
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T82367Fulranumab;化合物 FulranumabFulranumab
Fulranumab, a human IgG2 monoclonal antibody targeting nerve growth factor (NGF), is utilized in pain research [1].
价 格:¥电议型 号:T82367产 地:中国大陆
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T82170HSDAVFTDNYTRLRRQLAVRRYLNSILN-NH2;化合物 HSDAVFTDNYTRLRRQLAVRRYLNSILN-NH2HSDAVFTDNYTRLRRQLAVRRYLNSILN-NH
HSDAVFTDNYTRLRRQLAVRRYLNSILN-NH2 is a peptide with anti-inflammatory properties [1].
价 格:¥电议型 号:T82170产 地:中国大陆
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T81916LPLRF-NH2;化合物 LPLRF-NH2LPLRF-NH2
LPLRF-NH2, an RFamide peptide, exhibits an anorexigenic effect, elevates arterial blood pressure, and alters brainstem neuronal electrical activity [1] [2] [3].
价 格:¥电议型 号:T81916产 地:中国大陆
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T81782mLR12;化合物 mLR12mLR12
mLR12 is a Trem1 inhibitory peptide that reduces the incidence of aortic rupture in a mouse model of BAPN-induced Thoracic Aortic Aneurysm and Dissection (TAAD) [1].
价 格:¥电议型 号:T81782产 地:中国大陆
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T81707Nangibotide;化合物 NangibotideLR12;LR12
Nangibotide, a TREM-1 receptor inhibitor, modulates the innate immune response and has demonstrated the potential to reduce systemic and localized inflammatory reactions in rodent models of myocardial ischemia-reperfusion [1].
价 格:¥电议型 号:T81707产 地:中国大陆
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T81668NLRP3 agonist 1;化合物 NLRP3 agonist 1NLRP3 agonist 1
NLRP3 agonist 1 (compound 23) serves as a potent, orally active agent that activates Caspase-1 enzyme, leading to the cleavage of proinflammatory cytokines pro-IL-1β and pro-IL-18 into their active forms [1].
价 格:¥电议型 号:T81668产 地:中国大陆
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T81667NLRP3 agonist 2;化合物 NLRP3 agonist 2NLRP3 agonist 2
NLRP3 agonist 2 (compound 22) is an orally active agent that activates Caspase-1 in THP1 cells [1].
价 格:¥电议型 号:T81667产 地:中国大陆
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T81666NLRP3-IN-22;化合物 NLRP3-IN-22NLRP3-IN-22
NLRP3-IN-22 (Compound II-4) is an inhibitor of NLRP3, exhibiting a 67% inhibition rate at a concentration of 10 μM [1].
价 格:¥电议型 号:T81666产 地:中国大陆
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T81665NLRP3-IN-23;化合物 NLRP3-IN-23NLRP3-IN-23
NLRP3-IN-23 (Compound 15C) is an inhibitor that significantly impedes heme-mediated activation of the NLRP3 inflammasome at a concentration of 0.1 μM [1].
价 格:¥电议型 号:T81665产 地:中国大陆
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T81317Rabbit IgG1 kappa, Isotype Control;化合物 Rabbit IgG1 kappa, Isotype ControlRabbit IgG1 kappa, Isotype
Rabbit IgG1 kappa Isotype Control is a rabbit monoclonal antibody serving as an isotype control for Rabbit IgG1κ antibody.
价 格:¥电议型 号:T81317产 地:中国大陆
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T81059SWELYYPLRANL-NH2;化合物 SWELYYPLRANL-NH2SWELYYPLRANL-NH2
SWELYYPLRANL-NH2 is a dual antagonist of E-cadherin and N-cadherin, effectively inhibiting the binding of phage clones to both E-cad/Fc and N-cad/Fc chimeric proteins with IC50 values of 0.7 μM and 0.09 μM, respectively. This compound also impedes cell aggregation and has potential applications in enhancing drug delivery by increasing epithelial and endothelial permeability barriers [1].
价 格:¥电议型 号:T81059产 地:中国大陆
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T81058SWELYYPLRANL-NH2 TFA;化合物 SWELYYPLRANL-NH2 TFASWELYYPLRANL-NH2 TFA
SWELYYPLRANL-NH2 TFA acts as an antagonist to both E-cadherin and N-cadherin, with inhibitory effects on phage clone binding to E- or N-cad/Fc chimeric proteins, exhibiting IC50 values of 0.7 μM and 0.09 μM, respectively. Additionally, it disrupts cell aggregation and is utilized to enhance drug delivery by increasing the permeability of epithelial and endothelial barriers [1].
价 格:¥电议型 号:T81058产 地:中国大陆
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T80978TLR4 agonist-1;化合物 TLR4 agonist-1TLR4 agonist-1
TLR4 agonist-1 (compound 17a) serves as a potent activator of Toll-like Receptor 4 (TLR4) and stimulates the production of MIP-1β in RAW 264.7 and MM6 cells [1].
价 格:¥电议型 号:T80978产 地:中国大陆
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T80977TLR4 agonist-1 TEA;化合物 TLR4 agonist-1 TEATLR4 agonist-1 TEA
TLR4 agonist-1 (TEA, compound 17a) is a potent activator of Toll-like Receptor 4 (TLR4) and prompts the production of MIP-1β in RAW 264.7 and MM6 cells [1].
价 格:¥电议型 号:T80977产 地:中国大陆
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T80976TLR7/8 agonist 4 hydroxy-PEG6-acid;化合物 TLR7/8 agonist 4 hydroxy-PEG6-acidTLR7/8 agonist 4 hydroxy-PE
TLR7/8 agonist 4 hydroxy-PEG6-acid, a Drug-Linker Conjugate for ADCs, comprises the TLR7/8 agonist 4 and a hydroxy-PEG6-acid linker, suitable for the synthesis of antibody-drug conjugates (ADCs) [1].
价 格:¥电议型 号:T80976产 地:中国大陆
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T80962TPNQRQNVC;化合物 TPNQRQNVCLRH-1 peptide;LRH-1 peptide
TPNQRQNVC, a nonapeptide epitope of HLA-B0702, induces a CD8+ T cell immune response [1].
价 格:¥电议型 号:T80962产 地:中国大陆
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T80550N-myristoyl-RKRTLRRL;化合物 N-myristoyl-RKRTLRRLN-myristoyl-RKRTLRRL
N-myristoyl-RKRTLRRL is a compound that impedes the binding of protein kinase C (PKC) substrates and inhibits calcium (Ca2+)- and phosphatidylserine (PS)-dependent phosphorylation of histones, exhibiting an IC50 of 5 μM. Additionally, it demonstrates an inhibitory effect on histone phosphorylation with an IC50 of 80 μM [1] [2].
价 格:¥电议型 号:T80550产 地:中国大陆
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T80295GLR-19;化合物 GLR-19GLR-19
GLR-19 is an anti-HIV peptide with demonstrated antiviral activity against HSV-2 [1] [2].
价 格:¥电议型 号:T80295产 地:中国大陆
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T80239TFLLRNPNDK-NH2;化合物 TFLLRNPNDK-NH2TFLLRNPNDK-NH2
TFLLRNPNDK-NH2 is a biologically active peptide and a thrombin receptor activating peptide (TRAP). As a PAR-1 agonist, it reversibly binds to PAR-1, mimicking the ´tethered ligand´ created by thrombin through proteolytic substrate cleavage. It also induces increased liquid and protein permeability, similar to thrombin´s effect.
价 格:¥电议型 号:T80239产 地:中国大陆