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  • T80236TFLLRN-NH2；化合物 TFLLRN-NH2TFLLRN-NH2

    TFLLRN-NH2 is a biologically active peptide functioning as a PAR-1 agonist.

    价 格：￥电议型 号：T80236产 地：中国大陆

  • T80235YFLLRNP；化合物 YFLLRNPYFLLRNP

    YFLLRNP is a biologically active peptide functioning as a partial agonist of PAR-1, selectively activating the G12/13 signaling pathway. At low concentrations, YFLLRNP (60 μM) does not activate Gq or Gi pathways.

    价 格：￥电议型 号：T80235产 地：中国大陆

  • T79751TLR7 agonist 16；化合物 TLR7 agonist 16TLR7 agonist 16

    TLR7 agonist 16 (compound 16d) is a potent activator of TLR7 with an EC50 value of 18 nM. It effectively triggers the activation of both mouse macrophages and human peripheral blood mononuclear cells (hPBMCs) at low-nanomolar levels [1].

    价 格：￥电议型 号：T79751产 地：中国大陆

  • T79750TLR7 agonist 15；化合物 TLR7 agonist 15TLR7 agonist 15

    TLR7 agonist 15 (compound 16b) is a potent activator of mouse macrophages and hPBMCs, demonstrating an EC50 of 18 nM. It induces robust responses at low-nanomolar concentrations [1].

    价 格：￥电议型 号：T79750产 地：中国大陆

  • T7975Rhodamine B；罗丹明BRhodamineu00A0B|||Tetraethylrhodamine|||Brilliant Pink B|||Basic Violet 1|||Rhodamin

    Rhodamine B (Brilliant Pink B) is used as a tracer dye in water to determine the rate and direction of flow and transport.

    价 格：￥电议型 号：T7975产 地：中国大陆

  • T79749TLR7 agonist 14；化合物 TLR7 agonist 14TLR7 agonist 14

    Compound 17b, a TLR7 agonist also known as TLR7 agonist 14, exhibits high potency with an EC50 of 18 nM. It effectively activates mouse macrophages and human peripheral blood mononuclear cells (hPBMCs) at low-nanomolar concentrations [1].

    价 格：￥电议型 号：T79749产 地：中国大陆

  • T79746LRRK2-IN-10；化合物 LRRK2-IN-10LRRK2-IN-10

    LRRK2-IN-10 (compound 34) is a potent, mutation-selective, brain-penetrant inhibitor targeting G2019S-LRRK2 kinase with IC50 values of 11 nM for G2019S-LRRK2 pS935 and 5.2 nM for G2019S-LRRK2 pS1292. It holds promise for research into Parkinson´s disease [1].

    价 格：￥电议型 号：T79746产 地：中国大陆

  • T79733NLRP3-IN-20；化合物 NLRP3-IN-20NLRP3-IN-20

    NLRP3-IN-20 (compound 11) is an orally administered inhibitor targeting the NLRP3 inflammasome, exhibiting potent inhibition with an IC50 of 25 nM against IL-1β secretion. It possesses excellent pharmacokinetic properties and has shown significant efficacy in models of non-alcoholic steatohepatitis, fatal septic shock, and colitis [1].

    价 格：￥电议型 号：T79733产 地：中国大陆

  • T79696JT001 sodium；化合物 JT001 sodiumNLRP3-IN-19 sodium；NLRP3-IN-19 sodium

    JT001 (NLRP3-IN-19) sodium is a potent, specific, and orally active NLRP3 inhibitor that impedes the assembly of the NLRP3 inflammasome, thus curbing cytokine release and averting pyroptosis. It is utilized in research focused on nonalcoholic steatohepatitis and liver fibrosis [1].

    价 格：￥电议型 号：T79696产 地：中国大陆

  • T79695NLRP3-IN-19；化合物 NLRP3-IN-19NLRP3-IN-19；NLRP3-IN-19

    JT001 (NLRP3-IN-19) is a potent, specific, and orally active NLRP3 inhibitor that impedes the assembly of the NLRP3 inflammasome. This action results in the suppression of cytokine release and prevention of pyroptosis. JT001 is utilized in research on nonalcoholic steatohepatitis and liver fibrosis [1].

    价 格：￥电议型 号：T79695产 地：中国大陆

  • T79151TLR8 agonist 6；化合物 TLR8 agonist 6TLR8 agonist 6

    Compound A, a potent TLR8 agonist, exhibits an EC50 of 0.052 ?M and promotes the production of IL-12p40 in human PBMCs with an EC50 of 0.031 ?M. This compound is applicable for research in virus resistance, infection resistance, autoimmunity, and tumor studies [1].

    价 格：￥电议型 号：T79151产 地：中国大陆

  • T79069TLR7/8 agonist 9；化合物 TLR7/8 agonist 9TLR7/8 agonist 9

    TLR7/8 agonist 9 (Compound 25a), exhibiting EC50 values of 40 nM and 23 nM for hTLR7 and hTLR8 respectively, demonstrates anti-tumor properties and enhances the efficacy of PD-1/PD-L1 blockade treatments. This compound is utilized in cancer immunotherapy research [1].

    价 格：￥电议型 号：T79069产 地：中国大陆

  • T79068TLR7/8 agonist 8；化合物 TLR7/8 agonist 8TLR7/8 agonist 8

    TLR7/8 agonist 8 (compound 24m) is a potent dual agonist for toll-like receptors 7 and 8 (TLR7/8), exhibiting half-maximal effective concentrations (EC50s) of 27 nM for human TLR7 (hTLR7) and 12 nM for human TLR8 (hTLR8). This compound has been shown to enhance the efficacy of PD-1/PD-L1 inhibitors in antitumor activity [1].

    价 格：￥电议型 号：T79068产 地：中国大陆

  • T78894NLRP3-IN-21；化合物 NLRP3-IN-21NLRP3-IN-21

    NLRP3-IN-21 (compound L38) is an inhibitor of the NLRP3 inflammasome that possesses anti-inflammatory properties. It suppresses the activation of the NLRP3 inflammasome and pyroptosis by inhibiting gasdermin D cleavage, ASC oligomerization, and the assembly of the NLRP3 inflammasome [1].

    价 格：￥电议型 号：T78894产 地：中国大陆

  • T78545FLLRN；化合物 FLLRNTRAP-6 (2-6)；TRAP-6 (2-6)

    FLLRN is a biologically active peptide serving as a PAR1-specific antagonist.

    价 格：￥电议型 号：T78545产 地：中国大陆

  • T78537Cefetamet pivoxyl化合物 Cefetamet pivoxylRo 15-8075 free base

    Cefetamet pivoxyl, a cephalosporin antibiotic, effectively inhibits 355 enteropathogens, including Gram-negative bacteria (ausgenommen Pseudomonas aeruginosa) and Legionella pneumophila [1].

    价 格：￥电议型 号：T78537产 地：中国大陆

  • T78529Pelacarsen；化合物 PelacarsenTQJ230|||AKCEA-APO(a)-LRx|||ISIS 681257；TQJ230|||AKCEA-APO(a)-LRx|||ISIS 68

    Pelacarsen (AKCEA-APO(a)-LRx) is a hepatotropic antisense oligonucleotide targeting apolipoprotein(a) that effectively attenuates lipoprotein(a) levels by up to 80% and exhibits favorable tolerability [1].

    价 格：￥电议型 号：T78529产 地：中国大陆

  • T78338Rat IgG1 kappa, Isotype Control；化合物 Rat IgG1 kappa, Isotype ControlRat IgG1 kappa, Isotype Control

    Rat IgG1 kappa Isotype Control is a rat monoclonal antibody serving as an isotype control specific for Rat IgG1κ antibody.

    价 格：￥电议型 号：T78338产 地：中国大陆

  • T78180NLRP3-IN-18；化合物 NLRP3-IN-18NLRP3-IN-18

    NLRP3-IN-18, also known as compound 13, is a potent inhibitor of NLRP3, demonstrating an IC50 value of ≤1.0 ?M [1].

    价 格：￥电议型 号：T78180产 地：中国大陆

  • T78168NLRP3-IN-17；化合物 NLRP3-IN-17NLRP3-IN-17

    NLRP3-IN-17 is a potent, selective, and orally active inhibitor of the NLRP3 inflammasome, demonstrating an IC50 of 7 nM. It effectively inhibits NLRP3-dependent IL-1β secretion in mice, making it a valuable compound for research into chronic inflammatory diseases [1].

    价 格：￥电议型 号：T78168产 地：中国大陆

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