ҵ
ԱͣԱ
ѻƹ ȼ
(0 -40)ۣ
(41-90)ۣɽǢ̸
(91+ )ۣɳ
ƹԱ5
֤ʱ䣺
עţ ֤
˴ ֤
ҵͣ ֤
עʽ ֤
Ʒ86101
ι۴3751094
-
T7312AX20017AX 20017,AX20017,Inhibitor,Bacterial,inhibit,AX-20017
AX20017 is a small-molecule protein kinase G (PknG) inhibitor(IC50 : 0.39 M). It acts by blocking the proliferation of M. tuberculosis.
ţT7312 أй½
-
TN2100PratenseinInhibitor,Nuclear factor-kappaB,Nuclear factor-B,cognitive,inhibit,BDNF,synapse,Pratensei
Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.
ţTN2100 أй½
-
T9268UlinastatinUlinastatin
Ulinastatin is a multivalent Kunitz-type serine protease inhibitor with anti-inflammatory properties.
ţT9268 أй½
-
T25284DAC-2-25
DAC-2-25 is a Hydra head regeneration modulator. It acts by inducing a homeotic transformation in Hydra.
ţT25284 أй½
-
TP1882L1Orphanin FQ(1-11) acetate(178249-41-7 free base)Orphanin FQ(1 11) acetate(178249 41 7 free base),Orp
Peptide fragment containing amino acids 1-11 of Nociceptin. Potent agonist of the ORL1/KOR-3 receptor (Ki = 55 nM); displays no affinity for opioid receptors, including , , 1 and 3 receptors (Ki >1000 nM). Displays analgesic properties in CD-1 mice.
ţTP1882L1 أй½
-
T60032BRM/BRG1 ATP Inhibitor-2Epigenetic Reader Domain,Inhibitor,BRM/BRG1 ATP Inhibitor 2,inhibit,BRM/BRG1
BRM/BRG1 ATP Inhibitor-2 is an inhibitor of BRG1/BRM ATPase and can be used in studies about the treatment of BAF-related disorders.
ţT60032 أй½
-
T9743FEN1-IN-SC13FEN1 IN SC13,Inhibitor,FEN1INSC13,FEN-1-IN-SC13,inhibit
FEN1-IN-SC13 is a potent inhibitor of DNA fragmentation endonuclease 1 (FEN1)
ţT9743 أй½
-
T8595Practololreceptor,inhibit,arrhythmias,1-adrenergic,Practolol,Beta Receptor,Adrenergic Receptor,card
Practolol is a selective -adrenoceptor blocker.
ţT8595 أй½
-
T8796CAN508inhibit,CAN 508,ATP-competitive,Cyclin dependent kinase,esophageal,cells,CDK,CAN508,Inhibitor,
CAN508 is a potent, ATP-competitive CDK9/cyclin T1 inhibitor with an IC50 of 0.35 M. It is also a competitive inhibitor of Cdk2-cyclin E with respect to ATP, with Ki and IC50 values of 13.3 and 20 M, respectively.CAN508 exhibits a 38-fold selectivity for CDK9/cyclin T over other CDK/cyclin complexes. Antitumor activity.
ţT8796 أй½
-
T7741DS-1001binhibit,DS 1001b,Inhibitor,Isocitrate Dehydrogenase (IDH),DS-1001b,DS1001b
DS-1001b is an inhibitor of mutant IDH-1 (Isocitrate Dehydrogenase-1)
ţT7741 أй½
-
TQ0283RS102895CC chemokine receptor,CCR,Inhibitor,RS102895,inhibit,RS-102895,RS 102895
RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1.
ţTQ0283 أй½
-
T9041AES-350Histone deacetylases,AES 350,MV4-11,AES-350,Apoptosis,acute myeloid leukemia,AML,Inhibitor,in
AES-350 is a potent and orally active HDAC6 inhibitor(IC50 and a Ki of 0.0244 M and 0.035 M, respectively). It is also against HDAC-3, -8, and -11 in an enzymatic activity assay with IC50 values of 0.187 M, 0.245 M, and >1M, respectively. AES-350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research.
ţT9041 أй½
-
T61518TAK-653
TAK-653, an AMPA receptor potentiator with minimal agonistic activity, produces an antidepressant-like effect with a favorable safety profile in rats.
ţT61518 أй½
-
T6908NSC 228155Epidermal growth factor receptor,Histone Acetyltransferase,EGFR,HER1,HATs,inhibit,Inhibito
NSC228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.
ţT6908 أй½
-
T6924Riviciclib hydrochlorideinhibit,Inhibitor,Riviciclib,CDK,Riviciclib hydrochloride,Cyclin dependent k
P276-00 is a novel CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively. Phase 2/3.
ţT6924 أй½
-
T39389KDM2B-IN-2KDM2B IN 2,KDM-2B-IN-2,KDM2BIN2
KDM2B-IN-2 is a potent histone demethylase (kdm2b) inhibitor.
ţT39389 أй½
-
T8084Dimethyl 4-hydroxyisophthalateDimethyl 4-hydroxyisophthalate,inhibit,Dimethyl 4 hydroxyisophthalate,
Dimetghyl 4-Hydroxyisophthalate is a methyl salicylate analogue, used as a building block in the chemical synthesis.
ţT8084 أй½
-
T6767TCS7010Aurora Kinase,inhibit,TCS 7010,Apoptosis,TCS-7010,TCS7010,Inhibitor
Aurora A Inhibitor I is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay. It is 1000-fold more selective for Aurora A than Aurora B.
ţT6767 أй½
-
T14526Bemesetron
Bemesetron is a selective antagonist of 5-HT3 (IC50 = 0.33 nM) with neuroprotective effects.
ţT14526 أй½
-
T7815LAOD9604 acetate(221231-10-3 free base)AOD9604 acetate(221231103 free base),AOD-9604 acetate(221231-1
AOD9604 acetate is a potential anti-obesity peptide based on the human growth hormone.
ţT7815L أй½