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(41-90)ۣɽǢ̸
(91+ )ۣɳ
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עţ ֤
˴ ֤
ҵͣ ֤
עʽ ֤
Ʒ86101
ι۴3750130
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T12788R(+)-IAA-94
R(+)-IAA-94 is a potent indanyloxyacetic acid blocker of epithelial chloride channels. R(+)-IAA-94 inhibits Nef-sdAb19 (single-domain antibody) interaction and binds to negative factor (Nef).
ţT12788 أй½
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T9820GPI-1485neurofunctional,regeneration,Inhibitor,ligand,stroke,GPI-1485,GPI 1485,inhibit,immunophilin,
GPI-1485 (GM1485) is a nonimmunosuppressive immunophilin ligand, promoting neurofunctional improvement and neural regeneration following stroke.
ţT9820 أй½
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T10889CRTh2 antagonist 2CRTh2 antagonist 2,CRTh-2 antagonist 2
CRTh2 antagonist 2 is a selective and potent CRTH2 antagonist, IC5010 nM. CRTh2 antagonist 2 can be used to study the direction of androgenic alopecia.
ţT10889 أй½
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TQ0230BTK IN-1Btk,SNS062,Inhibitor,SNS-062,BTK IN 1,Bruton tyrosine kinase,SNS 062,inhibit,BTK IN-1,BTK IN
BTK IN-1 (SNS062 analog) is an effective BTK inhibitor (IC50: <100 nM).
ţTQ0230 أй½
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T21495Spinosyn Ainhibit,Inhibitor,Spinosyn A
Spinosyn A is a polyketide-derived macrolide produced by Saccharopolyspora spinosa and is an active ingredient in several commercial insecticides.
ţT21495 أй½
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T10502BenzcyclaneBenzcyclane
Benzcyclane is an inhibitor of platelet aggregation and also a vasodilator that can be used in a variety of peripheral circulation disorders.
ţT10502 أй½
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T7017WNK463Ser/Thr Protease,WNK 463,inhibit,WNK463,Serine proteases,Inhibitor,Serine endopeptidases,Threo
WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4).
ţT7017 أй½
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T9428HM43239HM43239,HM-43239
HM43239 is an orally active and selective FLT3 inhibitor with IC 50 s of 1.1 nM, 1.8 nM and 1.0 nM for FLT3 WT, FLT3 internal tandem duplication (ITD) and FLT3 D835Y kinases, respectively. HM43239 directly inhibits the kinase activity of FLT3 as a reversible Type I inhibitor and effectively modulates downstream p-STAT5 and p-ERK. HM43239 also demonstrated inhibition of SYK, JAK1/2 and TAK1. HM43239 inhibits the proliferation and induces the apoptosis of leukemic cells [1] [2] [3].
ţT9428 أй½
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T80435-Cholestane5 Cholestane,5Cholestane
5-Cholestane belongs to the class of organic compounds known as cholestane steroids.
ţT8043 أй½
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T9884EN523inhibit,EN-523,Inhibitor,non-catalytic,EN523,OTUB1 recruiter,EN 523,deubiquitinase,allosteric c
EN523 targets non-catalytic allosteric cysteine C23 in K48 ubiquitin-specific deuquitinase OTUB1.
ţT9884 أй½
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T97193-Hydroxyoctanoic Acid3Hydroxyoctanoic Acid,3 Hydroxyoctanoic Acid
3-Hydroxyoctanoic Acid is one of the hydroxy-carboxylic acids (HCAs) that serve as intermediates of energy metabolism. It is an agonist of the orphan receptor GPR109B.
ţT9719 أй½
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T2344LLY 344864 racemateLY 344864 racemate
LY 344864 racemate is a 5-HT1F receptor agonist.
ţT2344L أй½
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T9713-secretase inhibitor 11-Secretase inhibitor 11,CNS diseases,Alzheimers disease, secretase inhibi
-secretase inhibitor 11 is an inhibitor of -secretase and can be used as a lead compound for translational development of AD treatment.
ţT9713 أй½
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TP2338LCenupatide acetateCenupatide acetate
Cenupatide is an urokinase plasminogen activator receptor (uPAR) inhibitor for treating disorders associated altered cell migration, such as cancer.
ţTP2338L أй½
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T6476Dofetilidecardiovascular,potent,specific,class,antiarrhythmic,orally,Inhibitor,UK68789,UK-68789,Dofe
Dofetilide is a sulfonamide class III antiarrhythmic agent and potassium channel blocker. Dofetilide selectively blocks cardiac ion channels of the rapid component of the delayed rectifier potassium current Ikr. This antiarrhythmic agent prolongs cardiac action potential duration and effective refractory period due to delayed repolarization without affecting conduction velocity. This results in a normal sinus rhythm. Dofetilide is used in the treatment of atrial fibrillation and flutter.
ţT6476 أй½
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TN1030N-p-trans-CoumaroyltyramineInhibitor,Cholinesterase (ChE),Parasite,inhibit,N p trans Coumaroyltyrami
N-p-trans-Coumaroyltyramine is a natural product, is an acetylcholinesterase (AChE) inhibitor with an an IC50 of 122 M. N-p-trans-Coumaroyltyramine exhibits anti-trypanosomal activity with an IC50 of 13.3 M for T. brucei rhodesiense.
ţTN1030 أй½
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T25824ML400
ML400 is an allosteric inhibitor of LMPTP with an EC50 of 1M. ML400 displays good cell-based activity and rodent pharmacokinetics.
ţT25824 أй½
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T6582Mezlocillin SodiumBAY-f 1353,Mezlocillin Sodium,bacterial infection,gram-positive bacteria,Mezlocill
Mezlocillin sodium is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms.
ţT6582 أй½
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TN1519L(-)-Coclaurine hydrochloride
(-)-Coclaurine hydrochloride is an antagonist of nAChRs isolated from Sarcopetalum harveyanum.
ţTN1519L أй½