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T3646RSL3RSL3 1S;1S,3R-RSL3
RSL3 is a VDAC-independent ferroptosis activator with selectivity for tumor cells bearing oncogenic RAS. RSL3 is the inhibitor of the glutathione peroxidase 4, which can inhibit the cysteine/glutamate amino acid transporter system xc- that blocks GSH synt
价 格:¥电议型 号:T3646产 地:中国大陆
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T3627IQ-1S free acidIQ-1S;IQ-1;IQ-1S (free acid)
IQ-1S is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. IQ-1S can reduce inflammation and cartilage loss associated with CIA and can serve as a small-molecule modulator for mechanistic stu
价 格:¥电议型 号:T3627产 地:中国大陆
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T3593Src Inhibitor 1Src Kinase Inhibitor 1;Src-l1
Src Inhibitor 1 is a potent and selective dual site Src tyrosine kinase inhibitor.
价 格:¥电议型 号:T3593产 地:中国大陆
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T34532Sari 59-801Sari-59-801
Sari 59-801 is a novel, orally effective hypoglycemic compound that appears to act largely by stimulation of insulin release. SARI-59-801 was more potent in producing hypoglycemia (ED25 = 47 mg/kg) than their lean littermates (ED25 = 131 mg/kg).
价 格:¥电议型 号:T34532产 地:中国大陆
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T28754Sepin-1Sepin1;Sepin 1;2H-Benzimidazole, 2,2-dimethyl-5-nitro-, 1,3-dioxide
Sepin-1 is a noncompetitive inhibitor of separase with an IC50 of 14.8 ?M. Sepin-1 can inhibit the growth of breast cancer xenograft tumors in mice and human cancer cell lines by inhibiting cell proliferation and inducing apoptosis.
价 格:¥电议型 号:T28754产 地:中国大陆
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T2450SANT-1SANT1;SANT 1
SANT-1 directly binds to Smoothened (Smo) receptor (Kd: 1.2 nM) and inhibits Smo agonist effects (IC50: 20 nM).
价 格:¥电议型 号:T2450产 地:中国大陆
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T2440IC261SU-5607
IC261 is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.
价 格:¥电议型 号:T2440产 地:中国大陆
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T2363STF-31STF31;STF 31
STF-31 is an inhibitor of glucose transporter 1 (GLUT1) with IC50 of 1 μM.
价 格:¥电议型 号:T2363产 地:中国大陆
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T21773SP-141SP 141
SP 141 is a MDM2 inhibitor.SP-141 promotes MDM2 auto-ubiquitination and degradation, with anticancer activity.
价 格:¥电议型 号:T21773产 地:中国大陆
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T2171SEW?2871SEW2871
Sphingosine-1-phosphate receptor 1 agonist SEW2871 prolongs heterotopic heart allograft survival in mice.
价 格:¥电议型 号:T2171产 地:中国大陆
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T1937Spautin-1Spautin 1
Spautin-1 is a novel autophagy inhibitor, IM inhibited the growth of K562 cells with IC50 of 1.03 μM. In contrast, co-treatment with Spautin-1 increased IM-induced inhibition of cell viability with IC50 of 0.45 μM.
价 格:¥电议型 号:T1937产 地:中国大陆
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T1831StemRegenin 1SR1
StemRegenin 1 is an aryl hydrocarbon receptor (AhR) inhibitor.
价 格:¥电议型 号:T1831产 地:中国大陆
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T15184E 2012(E)-1-[(1S)-1-(4-氟苯基)乙基]-3-[3-甲氧基-4-(4-甲基-1H-咪唑-1-YL)亚苄基]哌啶-2-酮
E2012 is a γ-secretase modulator (GSM). E2012 inhibits 3β-hydroxysterol Δ24-reductase (DHCR24) at the final step in the cholesterol biosynthesis. E 2012 aims at Alzheimer´s disease by reduction of amyloid β-42, and induces cataract following repeated dose
价 格:¥电议型 号:T15184产 地:中国大陆
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T13932TLR1N-[(1S)-2-甲基-1-(1-吡咯烷羰基)丙基]-苯丙酰胺
TLR1 is a cell-penetrating Toll/IL-1 receptor/resistance (TIR) domain/BB-Loop mimic and inhibits IL-1 receptor-mediated responses.
价 格:¥电议型 号:T13932产 地:中国大陆
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T12574PTC299Emvododstat;(4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]
PTC299 is an orally active inhibitor of VEGFA mRNA translation and selectively inhibits VEGF protein synthesis at the post-transcriptional level. PTC299 is also a potent inhibitor of dihydrolactate dehydrogenase (DHODH).
价 格:¥电议型 号:T12574产 地:中国大陆
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T10060(1S,2S,3R)-DT-061(1S,2S,3R)-DT-061
(1S,2S,3R)-DT-061 is an enantiomer of DT-061 which is an orally bioavailable activator of PP2A.
价 格:¥电议型 号:T10060产 地:美洲
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T10969DC1SMeDC1SMe
DC1 is an ADC cytotoxin, similar to the small groove-binding DNA alkylating agent CC-1065. DC1 can be used to synthesize antibody-drug conjugates targeted to the treatment of cancer. DC1Sme is a DC1 derivative with IC50 values of Ramos, Namalwa, HL60 / s
价 格:¥电议型 号:T10969产 地:美洲
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T12889SDZ 220-581SDZ 220-581
SDZ 220-581 is a potent, orally active and competitive antagonist of NMDA receptor(pKi : 7.7).
价 格:¥电议型 号:T12889产 地:美洲
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T12890SGK1-IN-1SGK1-IN-1
SGK1-IN-1 is a highly active and selective SGK-1 inhibitor(IC50 of 1 nM).
价 格:¥电议型 号:T12890产 地:美洲
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T12910Sigma-1 receptor antagonist 1Sigma-1 receptor antagonist 1
Sigma-1 receptor antagonist 1 is a potent and selective antagonist of sigma-1 receptor (σ1R) with Ki of 1.06 nM, has antineuropathic pain activity.
价 格:¥电议型 号:T12910产 地:美洲