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T2363STF-31STF-31,STF31,STF 31
STF-31 is an inhibitor of glucose transporter 1 (GLUT1) with IC50 of 1 μM.
价 格:¥电议型 号:T2363产 地:美洲
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T2450SANT-1SANT-1,SANT1,SANT 1
SANT-1 directly binds to Smoothened (Smo) receptor (Kd: 1.2 nM) and inhibits Smo agonist effects (IC50: 20 nM).
价 格:¥电议型 号:T2450产 地:美洲
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T2505S3I-201S3I-201,S3I201,S3I 201
S3I-201 is a selective Stat3 inhibitor (IC50: 86±33 μM) and low effect towards STAT1/5.
价 格:¥电议型 号:T2505产 地:美洲
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T5163SR1001SR1001
SR 1001 is an inverse agonist for RORα/RORγ (Kis: 172/111 nM).
价 格:¥电议型 号:T5163产 地:美洲
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T5169SGC-GAK-1SGC-GAK-1
SGC-GAK-1 is a selective cyclin G-associated kinase (GAK) inhibitor (Ki: 3.1 nM).
价 格:¥电议型 号:T5169产 地:美洲
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T5180SKA-31SKA-31,SKA31,SKA 31
SKA 31 is an activator of KCa3.1 and KCa2 channels (EC50s: 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2 respectively).
价 格:¥电议型 号:T5180产 地:美洲
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T5194SPHINX31SPHINX31
SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).
价 格:¥电议型 号:T5194产 地:美洲
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T5349SCR-1481B1SCR-1481B1,c-Met inhibitor 2,
SCR-1481B1 has activity against cancers dependent on Met activation and also has activity against cancers as a VEGFR inhibitor
价 格:¥电议型 号:T5349产 地:美洲
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T5831Selective PI3Kδ Inhibitor 1Selective PI3Kδ Inhibitor 1
Selective PI3Kδ Inhibitor 1 is a PI3Kδ Inhibitor(IC50 = 0.9 nM).
价 格:¥电议型 号:T5831产 地:美洲
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T8706STAMBP-IN-1;化合物 STAMBP-IN-1STAMBP-IN-1
STAMBP-IN-1 is a novel selective antagonist of deubiquitinase STAM-binding protein (STAMBP), decreasing NALP7 protein levels and suppressing IL-1β release after TLR agonism.
价 格:¥电议型 号:T8706产 地:中国大陆
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T83910S1PL-IN-31;化合物 S1PL-IN-31Sphingosine-1-Phosphate Lyase Inhibitor 31|||S1PL Inhibitor 31|||S1P Lyase
S1PL-IN-31 is a dual-function chemical compound acting as an inhibitor of sphingosine-1-phosphate (S1P) lyase with an IC50 value of 210 nM and as an antagonist of the Smoothened (Smo) receptor with an IC50 of 440 nM. Demonstrating therapeutic potential, this compound, at a dosage of 2 mg/kg per day, effectively mitigates cervical and thoracic lymphocyte infiltration and neuromuscular weakness in rats suffering from experimental autoimmune encephalomyelitis (EAE), a condition triggered by the MOG
价 格:¥电议型 号:T83910产 地:中国大陆
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T83864Plipastatin A1;化合物 Plipastatin A1SNA-60-367-3|||Fengycin IX;SNA-60-367-3|||Fengycin IX
Plipastatin A1, a lipopeptide isolated from B. cereus, demonstrates enzyme inhibitory and immunosuppressant properties. It effectively inhibits enzymes phospholipase A2 (PLA2), phospholipase C (PLC), and phospholipase D (PLD) with half-maximal inhibitory concentrations (IC50s) of 2.9, 1.3, and 1.4 ?M, respectively. Additionally, at a concentration of 100 ?g/ml, plipastatin A1 inhibits lipopolysaccharide (LPS)-induced B cell blastogenesis and T cell blastogenesis triggered by concanavalin A. In v
价 格:¥电议型 号:T83864产 地:中国大陆
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T83658SQLE-IN-1;SQLE 抑制剂1SQLE-IN-1
SQLE-IN-1 is a squalene epoxidase (SQLE) inhibitor with anti-tumor activity. It can inhibit the proliferation and migration of liver cancer cell line Huh7, inhibit the production of cellular cholesterol, and increase the expression of the tumor suppressor gene PTEN. expression, inhibiting the protein expression of PI3K and AKT.
价 格:¥电议型 号:T83658产 地:中国大陆
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T83615S5A1;化合物 S5A1S5A1
S5A1 is a synthetic steroid used in the study of diabetes.
价 格:¥电议型 号:T83615产 地:中国大陆
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T81218SAP1;化合物 SAP1SAP1
SAP1 is a bioactive peptide that inhibits viral entry into cells.
价 格:¥电议型 号:T81218产 地:中国大陆
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T81199SBP-1;化合物 SBP-1SBP-1
SBP-1, a sulfite bioluminescent probe (SBP), demonstrates excellent responsivity, selectivity, and sensitivity for sulfite detection. Its sulfite recognition is predicated on a sulfite-mediated intramolecular cleavage reaction mechanism. Applicable in living animals, SBP-1 can detect both exogenous and endogenous sulfite and is capable of quantitative sulfite measurement within a specified concentration range in solution [1].
价 格:¥电议型 号:T81199产 地:中国大陆
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T81181sEH/FLAP-IN-1;化合物 sEH/FLAP-IN-1sEH/FLAP-IN-1
sEH/FLAP-IN-1 (Compound 46A) serves as a dual inhibitor targeting both sEH and FLAP. It effectively suppresses 5-LOX product formation with an EC50 of 11 nM in SACM-stimulated PBMCs and also inhibits sEH activity (EC50: 18 nM) as well as thromboxane production. This compound is utilized in the study of inflammatory diseases [1].
价 格:¥电议型 号:T81181产 地:中国大陆
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T81175SETD7-IN-1;化合物 SETD7-IN-1SETD7-IN-1
SETD7-IN-1 (compound 7), a PFI-2 analogue, acts as both a substrate and inhibitor of histone lysine methyltransferase SETD7, exhibiting an inhibitory concentration (IC50) of 0.96 ± 0.10 ?M [1].
价 格:¥电议型 号:T81175产 地:中国大陆
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T81172Sex Pheromone Inhibitor iPD1;化合物 Sex Pheromone Inhibitor iPD1Sex Pheromone Inhibitor iPD1
Sex Pheromone Inhibitor iPD1 is a compound that functions as an inhibitor of the sex pheromone cPD1 [1].
价 格:¥电议型 号:T81172产 地:中国大陆
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T81171SH491;化合物 SH491SH491
SH491 (Compound 33) serves as an antiosteoporosis agent, effectively inhibiting RANKL-induced osteoclast differentiation in bone-marrow-derived monocytes (BMMs) with an IC50 of 11.8 nM. Additionally, SH491 suppresses the expression of genes and proteins related to osteoclastogenesis, specifically TRAP, CTSK, MMP-9, and ATPase v0d2 [1].
价 格:¥电议型 号:T81171产 地:中国大陆