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T11759Kif15-IN-2Kif15-IN-2
Kif15-IN-2 is used for the research of cellular proliferative diseases. Kif15-IN-2 is an inhibitor of the mitotic kinesin Kif15.
价 格:¥电议型 号:T11759产 地:美洲
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T13194CSF1R-IN-2CSF1R-IN-2
CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor(IC50 of 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).
价 格:¥电议型 号:T13194产 地:美洲
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T13324VUF11207 fumarateVUF11207 fumarate
VUF11207 fumarate is an agonist of CXCR7 and a high-potency ligand of CXCR7 (pKi of 8.1).
价 格:¥电议型 号:T13324产 地:美洲
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T15239EpristerideEpristeride,ONO-9302,SKF105657
Epristeride is a novel inhibor of 5α-reductase.
价 格:¥电议型 号:T15239产 地:美洲
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T15266F16F16
F16 is a mitochondriotoxic compound and triggers apoptosis or necrosis depending on the genetic background of the target carcinoma cell. F16 is a potent growth inhibitor of the neu-overexpressing cells. It also selectively inhibits the proliferation of ma
价 格:¥电议型 号:T15266产 地:美洲
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T15661Kif15-IN-1Kif15-IN-1
Kif15-IN-1 is an inhibitor of the mitotic Kinesin family member 15 (Kif15). Kif15-IN-1 is used for the research of cellular proliferative diseases.
价 格:¥电议型 号:T15661产 地:美洲
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T15803LY223982LY223982,CGS23131,SKF107324
LY223982 is an effective and specific inhibitor of the leukotriene B4 receptor (IC50: 13.2 nM). It also can against [3H]LTB4 binding to LTB4 receptor.
价 格:¥电议型 号:T15803产 地:美洲
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T2127OF-1OF-1,OF1,OF 1
OF-1 is a potent inhibitor of BRPF1B and BRPF2 bromodomain.
价 格:¥电议型 号:T2127产 地:美洲
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T6513Bisindolylmaleimide IBisindolylmaleimide I,Go 6850,GF109203X
GF109203X is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.
价 格:¥电议型 号:T6513产 地:美洲
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T83670F1 TFA;化合物 F1 TFATat-IKIP (46-60)|||Tat-Inhibitor of NF-κB Kinase-interacting Peptide;Tat-IKIP (46-6
F1, an anti-inflammatory peptide, incorporates the HIV-1 Tat protein transduction domain linked with a 15-amino acid sequence from residues 46-60 of the inhibitor of NF-κB kinase-interacting peptide (IKIP). It effectively blocks LPS-induced phosphorylation of IκB kinase α (IKKα) and IKKβ, along with the nuclear translocation of NF-κB (p65) in mouse peritoneal macrophages at 5 ?M concentration. F1, administered at 5 mg/kg in vivo, significantly reduces IL-6, TNF-α, and IL-1β serum levels and enha
价 格:¥电议型 号:T83670产 地:中国大陆
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T836622,3-dinor-8-iso Prostaglandin F1α;化合物 2,3-dinor-8-iso Prostaglandin F1α2,3-dinor-8-iso PGF1α|||2,3-d
2,3-Dinor-8-iso Prostaglandin F1α (2,3-dinor-8-iso PGF1α), an isoprostane and active metabolite of arachidonic acid deriving its formation from non-enzymatic free radical peroxidation, acts as an active metabolite of the platelet aggregation inhibitor 8-iso PGF2α. This compound exhibits vasoconstrictive properties in isolated porcine retinal and brain microvessels with EC50 values of 12.8 and 18.5 nM, respectively, yet it does not cause contraction in isolated rat aortic rings at a concentration
价 格:¥电议型 号:T83662产 地:中国大陆
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T82603DCAF1 binder 2;化合物 DCAF1 binder 2DCAF1 binder 2
DCAF1 Binder 2, an E3 ligase ligand, is implicated in BRD9, kinase, and selective Bruton´s tyrosine kinase (BTK) degradation.
价 格:¥电议型 号:T82603产 地:中国大陆
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T82422F1874-108;化合物 F1874-108F1874-108
F1874-108 functions as an inhibitor of both brassinosteroid biosynthesis and signal transduction [1].
价 格:¥电议型 号:T82422产 地:中国大陆
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T81853Marstenacisside F1;化合物 Marstenacisside F1Marstenacisside F1
Marstenacisside F1, a polyoxypregnanoside derivative of Tenacigenin B with anti-inflammatory properties, has been isolated from Marsdenia tenacissima. It suppresses lipopolysaccharide-induced nitric oxide (NO) production in RAW 264.7 cells.
价 格:¥电议型 号:T81853产 地:中国大陆
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T79793CRF1 receptor antagonist-1;化合物 CRF1 receptor antagonist-1CRF1 receptor antagonist-1
CRF1 Receptor Antagonist-1 (Compound 2), a CRF1 receptor antagonist, is utilized in research pertaining to congenital adrenal hyperplasia (CAH) [1].
价 格:¥电议型 号:T79793产 地:中国大陆
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T79472CSF1R-IN-17;化合物 CSF1R-IN-17CSF1R-IN-17
CSF1R-IN-17 (compound 9) is a potent, selective antagonist of CSF1R, exhibiting an inhibition concentration half-maximum (IC50) of 0.2 nM. It is capable of inhibiting osteoclast differentiation [1].
价 格:¥电议型 号:T79472产 地:中国大陆
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T78721Smurf1-IN-1;化合物 Smurf1-IN-1Smurf1-IN-1
Smurf1-IN-1, a selective E3 ubiquitin protein ligase 1 (SMURF1) inhibitor, exhibits oral activity with an IC50 of 92 nM and demonstrates considerable efficacy in a rat model of pulmonary hypertension [1].
价 格:¥电议型 号:T78721产 地:中国大陆
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T78236MuRF1-IN-2;化合物 MuRF1-IN-2MuRF1-IN-2
MuRF1-IN-2 (Example 3) serves as a MuRF1 inhibitor, applicable for investigating conditions associated with muscle wasting, including both skeletal and cardiac muscle atrophy [1].
价 格:¥电议型 号:T78236产 地:中国大陆
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T77965DCAF1 binder 1;化合物 DCAF1 binder 1DCAF1 binder 1
DCAF1 Binder 1 selectively targets the CRL4 DCAF1 E3 ligase complex as a ligand, playing a role in targeted protein degradation (TPD) [1].
价 格:¥电议型 号:T77965产 地:中国大陆
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T77932PF15 TFA;化合物 PF15 TFAPF15 TFA
PF15 TFA, a PROTAC targeting FLT3 kinase and CRBN, exhibits selective degradation of FLT3-ITD with a DC50 of 76.7 nM. The compound potently suppresses proliferation in FLT3-ITD-positive cells, reduces phosphorylation levels of FLT3 and STAT5, and demonstrates inhibition of tumor growth in murine leukemia models [1].
价 格:¥电议型 号:T77932产 地:中国大陆