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T62318CSF1R-IN-9;化合物 CSF1R-IN-9CSF1R-IN-9
CSF1R-IN-9 (Compound 46) is a CSF-1R inhibitor (IC50: 0.028 μM).
价 格:¥电议型 号:T62318产 地:中国大陆
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T62313CSF1R-IN-10;化合物 CSF1R-IN-10CSF1R-IN-10
CSF1R-IN-10 (Compound 48) is a CSF-1R inhibitor (IC50: 0.005 μM).
价 格:¥电议型 号:T62313产 地:中国大陆
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T62190CSF1R-IN-7;化合物 CSF1R-IN-7CSF1R-IN-7
CSF1R-IN-7 (Formula I) is a CSF-1R inhibitor that can be used to study Alzheimer´s disease.
价 格:¥电议型 号:T62190产 地:中国大陆
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T62187CSF1R-IN-6;化合物 CSF1R-IN-6CSF1R-IN-6
CSF1R-IN-6 is a potent inhibitor of CSF1R. CSF1R-IN-6 is a potent inhibitor of CSF1R, which is expressed in macrophages and is dependent on the CSF-1/CSF-1R signalling pathway for survival and differentiation of macrophages. Compound 5).
价 格:¥电议型 号:T62187产 地:中国大陆
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T62171HDAC8/BRPF1-IN-1;化合物 HDAC8/BRPF1-IN-1HDAC8/BRPF1-IN-1
HDAC8/BRPF1-IN-1 (Compound 23a) is a dual HDAC8 and BRPF1 inhibitor that acts on human HDAC8 (IC50: 443 nM) and human BRPF1 (Kd: 67 nM). HDAC8/BRPF1-IN-1 has low in vitro activity against HDAC1 and 6.
价 格:¥电议型 号:T62171产 地:中国大陆
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T62118KIF18A-IN-4;化合物 KIF18A-IN-4KIF18A-IN-4
KIF18A-IN-4 is a moderately potent non-competitive KIF18A inhibitor of ATP and microtubule with an IC50 of 6.16 μM. KIF18A-IN-4 selectively acts on a large number of mitotic kinesins and kinases, with no direct effect on microtubule protein assembly. KIF18A-IN-4 shows anti-tumour effects.
价 格:¥电议型 号:T62118产 地:中国大陆
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T61893CSF1R-IN-12;化合物 CSF1R-IN-12CSF1R-IN-12
CSF1R-IN-12 is an effective CSF1R inhibitor. CSF1R-IN-12 has research potential in cancer diseases.
价 格:¥电议型 号:T61893产 地:中国大陆
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T61727HDAC6/8/BRPF1-IN-1;化合物 HDAC6/8/BRPF1-IN-1HDAC6/8/BRPF1-IN-1
HDAC6/8/BRPF1-IN-1 is a dual inhibitor that targets HDAC6, HDAC8, and the bromodomain and PHD finger containing protein 1 (BRPF1). It exhibits inhibitory activity against HDAC1, HDAC6, and HDAC8 with IC50 values of 797 nM, 344 nM, and 908 nM, respectively. In addition, it inhibits BRPF1 with a Kd value of 175.2 nM. This compound is utilized in cancer research [1].
价 格:¥电议型 号:T61727产 地:中国大陆
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T61554CSF1R-IN-13;化合物 CSF1R-IN-13CSF1R-IN-13
CSF1R-IN-13 is a powerful CSF1R inhibitor with potential applications in researching cancer diseases [1]. CSF1R, also known as colony stimulating factor 1 receptor, is a critical growth factor that regulates various cell types, including bone marrow progenitor cells, monocytes, macrophages, and giants [1]. CSF1R-IN-13 shows promise in furthering our understanding of cancer-related disorders (WO2019134661A1, compound 32) [1].
价 格:¥电议型 号:T61554产 地:中国大陆
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T61540F15845;化合物 F15845F15845
F 15845 is a potent and persistent blocker of the sodium current. It possesses cardioprotective properties and exhibits both anti-ischemic activity and short- and long-term cardioprotection following myocardial infarction. Furthermore, F 15845 finds utility in the investigation of myocardial functional impairment [1].
价 格:¥电议型 号:T61540产 地:中国大陆
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T61112SLF1081851;化合物SLF1081851SLF1081851
SLF1081851 is a Spns2 inhibitor. SLF1081851 inhibits S1P release with IC50 of 1.93 μM.
价 格:¥电议型 号:T61112产 地:中国大陆
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T60026KIF18A-IN-2;化合物KIF18A-IN-2KIF18A-IN-2
KIF18A-IN-2 is an inhibitor of mitotic kinesin Kif18A with IC50 of 28 nM and can be used in studies about chromosomal instability-associated vulnerabilities.
价 格:¥电议型 号:T60026产 地:中国大陆
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T4308F1063-0967;化合物F1063-0967F1063-0967
F1063-0967 is a Dual-specificity phosphatase 26 (DUSP26) inhibitor with an IC50 of 11.62 μM.
价 格:¥电议型 号:T4308产 地:中国大陆
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T4125HSF1A;化合物HSF1AHSF1A
HSF1A is a cell-permeable activator of HSF1 that protects mammalian cells against stress-induced apoptosis.
价 格:¥电议型 号:T4125产 地:中国大陆
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T40232KIF18A-IN-1;KIF18A-IN-1KIF18A-IN-1;KIF18A-IN-1
KIF18A-IN-1 is a potent inhibitor of the mitotic kinesin KIF18A. This compound demonstrates significant anti-tumor properties.
价 格:¥电议型 号:T40232产 地:中国大陆
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T39947WSF1-IN-1WSF1-IN-1WSF1-IN-1
WSF1-IN-1 (compound 136) is an orally active inhibitor of WSF1, intended for the study of WSF1-related tumors in patients with Wolfram syndrome (WS). In HepG2 parental and HepG2 WFS1 KO cell lines, WSF1-IN-1 has demonstrated IC50 values of 0.33 μM and >27 μM, respectively.
价 格:¥电议型 号:T39947产 地:中国大陆
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T3963VUF10460;化合物VUF10460VUF10460
VUF10460 is a non-imidazole histamine H4 receptor agonist.
价 格:¥电议型 号:T3963产 地:中国大陆
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T3920Pseudoginsenoside F11;拟人参皂苷 F11Ginsenoside A1;Ginsenoside A1|||拟人参皂苷 F11|||拟人参皂苷F11
Pseudoginsenoside F11 (Ginsenoside A1) is a component of Panax quinquefolium (American ginseng) which main pharmacological activities are positive inotropic effect on isolated heart function, good therapeutic effect on myocardial ischemia, and good protective effect on cardio-cerebrovascular system and nervous system.
价 格:¥电议型 号:T3920产 地:中国大陆
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T3799015-keto Prostaglandin F1α;15-keto Prostaglandin F1α15-keto Prostaglandin F1α;15-keto Prostaglandin F
15-keto PGF1α is the initial metabolite of PGF1α via 15-hydroxy PGDH. In mammals, oxidation of C-15 markedly attenuates receptor binding and activity. In fish, the 15-keto compounds serve as post-ovulatory pheromones and are more active than the parent prostaglandins.
价 格:¥电议型 号:T37990产 地:中国大陆
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T37919Prostaglandin F1α;Prostaglandin F1αPGF1α|||Prostaglandin F1α;PGF1α|||Prostaglandin F1α
Prostaglandin F1α (PGF1α) is the putative metabolite of dihomo-γ-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway. Both PGF1α and PGF2α have been shown to act as priming pheromones for male Atlantic salmon with a threshold concentration of 10-11 M. [1] PGF1α binds to the ovine corpus luteum FP receptor at only 8% of the relative potency of PGF2α. [2] It is only half as active as PGF2α in inducing human respiratory smooth muscle contractions in vitro. [3]
价 格:¥电议型 号:T37919产 地:中国大陆