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  • T77767L1GLF16 HCl；GLF16 盐酸盐GLF16 HCl

    GLF16 HCl is a fluorophore-coupled Sudan Black B analog that allows rapid detection, isolation and real-time tracking of senescent cells by fluorescence microscopy and flow cytometry.

    价 格：￥电议型 号：T77767L1产 地：中国大陆

  • T77767LGLF16 FA；GLF16甲酸盐GLF16 FA

    GLF16 FA is a hydrophilic fluorescent SBB analogue for rapid detection of senescent cells using flow cytometry and live cell sorting.

    价 格：￥电议型 号：T77767L产 地：中国大陆

  • T77745N6F11；化合物N6F11N6F11|||N6F11|||N6F11；N6F11|||N6F11|||N6F11

    N6F11 is a novel, selective and potent inducer of iron death with anticancer and antitumour activity that promotes GPX4 degradation by binding to TRIM25 in cancer cells.N6F11 can be used to study pancreatic cancer.

    价 格：￥电议型 号：T77745产 地：中国大陆

  • T76866Icrucumab；艾芦库单抗LY 3012212|||IMC-18F1；LY 3012212|||IMC-18F1

    Icrucumab ( IMC-18F1) is a humanized IgG1 monoclonal antibody targeting vascular endothelial growth factor receptor-1.Icrucumab has antitumor activity.Icrucumab has been studied in metastatic colon cancer.

    价 格：￥电议型 号：T76866产 地：中国大陆

  • T76504CKLF1-C19；化合物 CKLF1-C19CKLF1-C19

    CKLF1-C19, the C-terminal peptide of human chemokine-like factor 1 (CKLF1), interacts with CCR4 and inhibits chemotaxis induced by CKLF1 and CCL17. It also suppresses allergic lung inflammation by inhibiting chemotaxis mediated by CCR3 and CCR4 [1].

    价 格：￥电议型 号：T76504产 地：中国大陆

  • T76245LCKLF1-C27 TFA；化合物 CKLF1-C27 TFACKLF1-C27 TFA

    CKLF1-C27 TFA, a C-terminal peptide of CKLF1, binds to CCR4 receptor and activates ERK1/2 pathway. CKLF1-C27 TFA can abrogate the effect of CKLF1 on cells by competing for CCR4 receptor. CKLF1-C27 TFA shows great effect on promoting proliferation on HUVECs. CKLF1-C27 TFA has?the?potential?for?psoriasis?research [1] .

    价 格：￥电议型 号：T76245L产 地：中国大陆

  • T76245CKLF1-C27；化合物 CKLF1-C27CKLF1-C27

    CKLF1-C27, a C-terminal peptide of CKLF1, effectively binds to and activates the CCR4 receptor, thereby triggering the ERK1/2 pathway. It competes with CKLF1 for the CCR4 receptor, neutralizing CKLF1´s cellular effects. Furthermore, CKLF1-C27 significantly promotes the proliferation of HUVECs and holds promise for psoriasis research [1].

    价 格：￥电议型 号：T76245产 地：中国大陆

  • T76227LS-BF1；化合物 LS-BF1LS-BF1

    LS-BF1, a stable and low-toxicity cationic antimicrobial peptide, exhibits broad-spectrum antibacterial activity that encompasses the notorious ESKAPE pathogens through a cell membrane disruption mechanism. The compound demonstrates effective in vivo bacterial elimination in a mouse infection model[1].

    价 格：￥电议型 号：T76227产 地：中国大陆

  • T75782LF11 TFA；化合物 LF11 TFALF11 TFA

    LF11 TFA is a peptide with antibacterial activity [1] .

    价 格：￥电议型 号：T75782产 地：中国大陆

  • T74336YF135；化合物 YF135YF135

    YF135, a reversible-covalent KRAS G12C PROTAC, effectively induces the degradation of KRAS G12C and reduces phospho-ERK levels via the E3 ligase VHL-mediated proteasome pathway. Designed by integrating the KRAS G12C inhibitor 48 (compound 6d) as the ligand, YF135 utilizes the MRTX849 linkage VHL ligand scaffold.

    价 格：￥电议型 号：T74336产 地：中国大陆

  • T74271TRIM24/BRPF1-IN-2；化合物 TRIM24/BRPF1-IN-2TRIM24/BRPF1-IN-2

    TRIM24/BRPF1-IN-2 (compound 20l) is an effective dual inhibitor of TRIM24/BRPF1, demonstrating IC50 values of 0.98 μM for TRIM24 and 1.16 μM for BRPF1, respectively. It exhibits strong binding affinity to the bromodomains of TRIM24/BRPF1, making it a valuable tool for prostate cancer research [1].

    价 格：￥电议型 号：T74271产 地：中国大陆

  • T74259PF15；化合物 PF15PF15

    PF15, a selective FLT3-ITD degrader, serves as a PROTAC (proteolysis targeting chimera) tethering ligands for FLT3 kinase and CRBN. It exhibits a degradation concentration 50 (DC50) of 76.7 nM and notably impedes the proliferation of FLT3-ITD-positive cells. PF15 also reduces phosphorylation levels of FLT3 and STAT5 and demonstrates efficacy in inhibiting tumor growth in mouse models, suggesting potential applications in leukemia research [1].

    价 格：￥电议型 号：T74259产 地：中国大陆

  • T73659HLF1-11；化合物 HLF1-11HLF1-11

    HLF1-11, derived from human lactoferrin, serves as a broad-spectrum antimicrobial agent. It not only inhibits human MPO (myeloperoxidase) activity but also influences GM-CSF (granulocyte-macrophage colony-stimulating factor)-driven monocyte differentiation into macrophages, thereby augmenting immune responses [1] [2].

    价 格：￥电议型 号：T73659产 地：中国大陆

  • T73050KIF18A-IN-7；化合物 KIF18A-IN-7KIF18A-IN-7

    KIF18A-IN-7 is an orally active inhibitor targeting KIF18A, demonstrating potent inhibition with an IC50 value of 9.4 nM against the microtubule-dependent ATPase activity of KIF18A.

    价 格：￥电议型 号：T73050产 地：中国大陆

  • T7281F-15599；化合物F-15599NLX-101|||inhibit|||5-HT Receptor|||F15599|||Serotonin Receptor|||F-15599|||NLX 10

    F-15599 is a highly selective G-protein biased 5-HT1A receptor agonist(Ki : 3.4 nM).

    价 格：￥电议型 号：T7281产 地：中国大陆

  • T72776NR2F1 agonist 1；化合物 NR2F1 agonist 1NR2F1 agonist 1

    NR2F1 agonist 1, a specific nuclear receptor NR2F1 activator, initiates dormancy programs in cancer cells by upregulating NR2F1 and its target genes controlling dormancy. This compound promotes neural crest-like features and suppresses growth in head and neck squamous cell carcinoma (HNSCC) through NR2F1 activation. Moreover, NR2F1 agonist 1 demonstrates tumor growth inhibition in a mouse primary tumor model.

    价 格：￥电议型 号：T72776产 地：中国大陆

  • T72574Axl/Mer/CSF1R-IN-1；化合物 Axl/Mer/CSF1R-IN-1Axl/Mer/CSF1R-IN-1

    Axl/Mer-IN-1 is a compound that functions as an inhibitor for Axl/Mer receptor tyrosine kinase (Axl/Mer RTK) and CSF1R, exhibiting dissociation constants (Kds) of less than 0.1 μM.

    价 格：￥电议型 号：T72574产 地：中国大陆

  • T71876F1386-0303；化合物 F1386-0303F1386-0303

    F1386-0303 is a novel potent and selective MAP4K4 inhibitor.

    价 格：￥电议型 号：T71876产 地：中国大陆

  • T70872Smurf1 inhibitor 1；化合物 Smurf1 inhibitor 1Smurf1 inhibitor 1

    Smurf1 inhibitor 1 is a inhibitor that promotes bone formation.

    价 格：￥电议型 号：T70872产 地：中国大陆

  • T70591PF1070A；化合物 PF1070APF1070A

    PF1070A is a natural cyclic tetrapeptide HDAC Inhibitor through the inhibition of PfHDAC1 catalytic activity, potently inducing the synthesis of metallothionein.

    价 格：￥电议型 号：T70591产 地：中国大陆

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