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T8767PfDHODH-IN-2malaria,Dihydroorotate Dehydrogenase,inhibit,PfDHODH,3D7,Inhibitor,Plasmodium falciparum
PfDHODH-IN-2 is a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH, IC50 : 1.11 μM) inhibitor . It is used an antimalarial agent and can be used for the research of malaria
价 格:¥电议型 号:T8767产 地:中国大陆
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T10923CYP17-IN-1CYP17IN1,CYP17 IN 1,CYP-17-IN-1
CYP17-IN-1 is an effective oral inhibitor of CYP17 that can inhibit CYP17 in rats and humans with IC50 of 15.8 and 20.1 nM.
价 格:¥电议型 号:T10923产 地:中国大陆
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T9214ELOVL6-IN-1ELOVL6IN1,noncompetitive,orally,palmitoyl-CoA,potent,malonyl-CoA,ELOVL-6-IN-1,Inhibitor,s
ELOVL6-IN-1 is a potent, orally active and selective ELOVL6 inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse ELOVL6 activities, with an IC50 value of 0.350 μM. ELOVL6-IN-1 inhibits ELOVL6 in a noncompetitive manner for malonyl-CoA (Ki=994 nM) and palmitoyl-CoA[1].
价 格:¥电议型 号:T9214产 地:中国大陆
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T9978Glutathione synthesis-IN-1Glutathione synthesisIN1,Glutathione synthesis IN 1
Glutathione synthesis-IN-1 (DC-1) is a inhibitor of glutathione synthesis[1].
价 格:¥电议型 号:T9978产 地:中国大陆
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T60130USP5-IN-1USP5IN1
USP5-IN-1 (compound 64) is a potent deubiquitinase USP5 inhibitor, which binds to the USP5 ZnF-UBD with a KD of 2.8 μM and is selective over nine proteins containing structurally similar ZnF-UBD domains. USP5-IN-1 inhibits the USP5 catalytic cleavage of a di-ubiquitin substrate [1].
价 格:¥电议型 号:T60130产 地:中国大陆
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T39705ATG7-IN-1ATG7 IN 1,ATG7IN1,ATG-7-IN-1
ATG7-IN-1 is a selective ATG7 inhibitor with an IC50 of 62 nM.
价 格:¥电议型 号:T39705产 地:中国大陆
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T8310MMP-9-IN-1PEX,anti-metastatic,metastasis,MMP,Matrix metalloproteinases,tumor,MMP 9 IN 1,inhibit,MMP9
MMP-9-IN-1 is an inhibitor of specific matrix metalloproteinase-9 (MMP-9).
价 格:¥电议型 号:T8310产 地:中国大陆
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T8703yGsy2p-IN-1diseases,synthase,hGYS1,pyrazole,GSDs,yGsy2p,yGsy2pIN1,yGsy-2p-IN-1,glycogen,storage,yGsy
yGsy2p-IN-1 is a potent yeast glycogen synthase 2 (yGsy2p) and human glycogen synthase 1 (hGYS1) inhibitor. yGsy2p-IN-H23 a pyrazole inhibitor,and is used for glycogen storage diseases (GSDs)
价 格:¥电议型 号:T8703产 地:中国大陆
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T9863PKCiota-IN-2
PKCiota-IN-2 is a selective and potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.8 nM. PKCiota-IN-2 also inhibits PKC-α and PKC-ε with IC50s of 71 nM and 350 nM, respectively
价 格:¥电议型 号:T9863产 地:中国大陆
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T63536Dual FAAH/sEH-IN-1
Dual FAAH/sEH-IN-1 is a dual inhibitor of sEH (soluble epoxide hydrolase) (IC50: 9.6 nM) and FAAH (fatty acid amide hydrolase) (IC50: 7 nM) with high affinity and anti-inflammatory activity.
价 格:¥电议型 号:T63536产 地:中国大陆
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T10954DAGLβ-IN-1DAGLβIN1,DAGLβ IN 1
DAGLβ-IN-1 is a universal intermediate for designing DAGL tailored activity-based probes, and is an inhibitor of diacylglycerol lipase-β (DAGLβ).
价 格:¥电议型 号:T10954产 地:中国大陆
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T9103BVDV-IN-1inhibit,virus,non-nucleoside,BVDV IN 1,activity,bovine,viral,antiviral,inhibitor,BVDVIN1,DN
BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. It directly binds to a hydrophobic pocket of the BVDV RdRp. It has antiviral activity against BVDV resistant to NNI thiosemicarbazone (TSC).
价 格:¥电议型 号:T9103产 地:中国大陆
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T9215ELOVL6-IN-2ELOVL6IN2,ELOVL6 IN 2,plasma,inhibit,selective,ELOVL-6-IN-2,liver,dose-proportionally,Inh
ELOVL6-IN-2 is a orally active and selective ELOVL6 inhibitor.
价 格:¥电议型 号:T9215产 地:中国大陆
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T12684Radioprotectin-1
Radioprotectin-1 is a selective agonist of LPA2 with EC50 of 25 nM for murine LPA2 GPCR and exerts radioprotective and radiomitigative action.
价 格:¥电议型 号:T12684产 地:中国大陆
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T9094JMJD7-IN-1Inhibitor,Histone Demethylase,cancer,JMJD7,JMJD7 IN 1,inhibit,JMJD7IN1,JMJD-7-IN-1
JMJD7-IN-1 is a potent JMJD7 inhibitor, with an IC50 of 6.62 μM. JMJD7-IN-1 shows good inhibitory activity against cells expressing a high level of JMJD7.
价 格:¥电议型 号:T9094产 地:中国大陆
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T11757KHK-IN-2KHK IN 2,KHKIN2
KHK-IN-2 is a selective inhibitor of ketohexokinase with an IC50 value of 0.45 μM.
价 格:¥电议型 号:T11757产 地:中国大陆
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T10033COX-2-IN-1COX 2 IN 1,COX2IN1
COX-2-IN-1 is a potent and selective COX-2 inhibitor (IC50: 3.9 μM).
价 格:¥电议型 号:T10033产 地:中国大陆
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T60904ERCC1-XPF-IN-2
ERCC1-XPF-IN-2 is active in nucleotide excision repair, cisplatin enhancement and γH2AX assays. ERCC1-XPF-IN-2 is a potent inhibitor of ERCC1-XPF endonuclease with an IC 50 value of 0.6 μM [1].
价 格:¥电议型 号:T60904产 地:中国大陆
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T9564IRE1α kinase-IN-1endoribonuclease,Inositol requiring enzyme 1,cells,IRE1,oligomerization,IRE-1α kina
IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM. It displays 100-fold selectivity for IRE1α over the IRE1β isoform. It inhibits ER stress-induced IRE1α oligomerization and autophosphorylation, and also inhibits IRE1α RNase activity (IC50=80 nM)
价 格:¥电议型 号:T9564产 地:中国大陆