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T9641Aβ42-IN-2Aβ42 IN 2,Aβ42IN2
Aβ42-IN-2 is a γ-secretase modulator (patent WO2016070107, compound example 36). Aβ42-IN-2 exhibits an IC50 of 6.5 nM for Αβ42. Aβ42-IN-2 has research value in Alzheimer´s disease.
价 格:¥电议型 号:T9641产 地:中国大陆
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T12347p38-α MAPK-IN-1Inhibitor,inhibit,p-38-α MAPK-IN-1,Autophagy,p38α MAPKIN1,p38 MAPK,p38 α MAPK IN 1
p38-α MAPK-IN-1 is a MAPK14 (p38-α) inhibitor with IC50 of 2300 nM and 5500 nM in EFC displacement assay and HTRF assay,respectively.
价 格:¥电议型 号:T12347产 地:中国大陆
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T9700EZH2-IN-2EZH2IN2,EZH-2-IN-2,EZH2 IN 2
EZH2-IN-2 is a EZH2 inhibitor with an IC50 of 64 nM (Patent WO2018133795A1, Compound Example 69).
价 格:¥电议型 号:T9700产 地:中国大陆
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T9711OGT-IN-2OGT,mono- acylglycerol acyltransferase,articular diseases,Inhibitor,articular cartilage,Acyl
OGT-IN-2 is a potent O-GlcNAc transferase (OGT) inhibitor. OGT-IN-2 inhibits sOGT and ncOGT with IC50 values of 30 μM and 53 μM, respectively[1]. OGT-IN-2 can be used for the research of articular diseases[1].
价 格:¥电议型 号:T9711产 地:中国大陆
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T9377ASK1-IN-2colitis,ulcerative,signal-regulating,ASK1 IN 2,ASK1IN2,inhibit,MAP kinase kinase kinase, ME
ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM. ASK1-IN-2 can potentially be used as a therapeutic strategy for ulcerative colitis[1].
价 格:¥电议型 号:T9377产 地:中国大陆
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T11019DHODH-IN-1DHODHIN1,DHODH IN 1
DHODH-IN-1 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 25 nM. DHODH-IN-1 is an inhibitor of the pyrimidine biosynthetic pathway.
价 格:¥电议型 号:T11019产 地:中国大陆
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T12462PI3Kδ-IN-1PI3Kδ IN 1,PI-3Kδ-IN-1,PI3KδIN1
PI3Kδ-IN-1 is an efficacious PI3Kδ inhibitor (IC50 of 1.7 nM).
价 格:¥电议型 号:T12462产 地:中国大陆
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T7639Deltorphin 2inhibit,Deltorphin2,Inhibitor,Deltorphin 2,Opioid Receptor,Deltorphin-2
Deltorphin 2(TFA) is an agonist of δ opioid receptor(IC50:0.41 nM)
价 格:¥电议型 号:T7639产 地:中国大陆
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T14283amyloid P-IN-1amyloid P IN 1,amyloid PIN1
amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P components such as Alzheimer´s disease, amyloidosis, osteoarthritis, and type 2 diabetes mellitus.
价 格:¥电议型 号:T14283产 地:中国大陆
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T8218Vanin-1-IN-1Inhibitor,inhibit,Vanin 1 IN 1,Vanin1IN1
Vanin-1-IN-1 is an vanin-1 enzyme inhibitor.
价 格:¥电议型 号:T8218产 地:中国大陆
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T7082HDAC8-IN-1HDAC-8-IN-1,HDAC8IN1,Histone deacetylases,Inhibitor,inhibit,HDAC,HDAC8 IN 1
MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5). HDAC8-IN-1 exhibits cytotoxicity against human lung CL1-5 cells without significant cytotoxicity for normal IMR-90 cells[1].
价 格:¥电议型 号:T7082产 地:中国大陆
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T9245TRPM4-IN-1TRP Channel,Transient receptor potential channels,non-selective,TRPM4IN1,diseases,TRPM4,in
TRPM4-IN-1 is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.
价 格:¥电议型 号:T9245产 地:中国大陆
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T9696β-catenin-IN-2HCT116,inhibit,cancer,β-catenin,cell,Beta catenin,HT-29,Tcf/4,Colorectal,Inhibitor,β c
β-catenin-IN-2 is a potent inhibitor of β-catenin that can be used in colorectal cancer research.
价 格:¥电议型 号:T9696产 地:中国大陆
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T7672MD2-TLR4-IN-1inhibit,Toll-like Receptor (TLR),MD2 TLR4 IN 1,MD2TLR4IN1,MD-2-TLR4-IN-1,Inhibitor
MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex inhibitor.
价 格:¥电议型 号:T7672产 地:中国大陆
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T10905CXCR2-IN-1CXCR-2-IN-1,CXCR2 IN 1,CXCR2IN1
CXCR2-IN-1 has a pIC50 of 9.3 and is a CXCR2 antagonist of the central nervous system penetration agent.
价 格:¥电议型 号:T10905产 地:中国大陆
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T67775Enpp/Carbonic anhydrase-IN-1Enpp/CarbonicanhydraseIN1
Enpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent inhibitor of Enpp and carbonic anhydrase. Enpp/Carbonic anhydrase-IN-1 exhibits IC50s of 1.36, 1.35, 3.00, 0.88, 1.02 ?M for NPP1, NPP2, NPP3, CA-II, CA-IX respectively. Enpp/Carbonic anhydrase-IN-1 exhibits selective antiproliferative activity for cancer cells.
价 格:¥电议型 号:T67775产 地:中国大陆
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T8951JTP 0819958 - HOIPIN-1JTP 0819958 HOIPIN1,JTP 0819958 HOIPIN 1
JTP-0819958 is a selective linear ubiquitin chain assembly complex (LUBAC) inhibitor with an IC50 of 2.8 μM[1]. JTP-0819958 suppress LUBAC-mediated NF-kB activation in vitro[2].
价 格:¥电议型 号:T8951产 地:中国大陆
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T7263SMS2-IN-2Inhibitor,SMS-2-IN-2,SMS2 IN 2,SMS2IN2,inhibit
SMS2-IN-2 is a potent, selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor, (IC50s of 100 and 56 μM for SMS2 and SMS1, respectively). SMS2-IN-2 has anti-chronic inflammatory activity.
价 格:¥电议型 号:T7263产 地:中国大陆
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T9560MAO-B-IN-2MAO B IN 2,MAOBIN2
MAO-B-IN-2 is a selective and competitive inhibitor of MAO-B and BChE with IC 50 values of 0.51 and 7.00 μM, respectively. MAO-B-IN-2 attenuates H2O2-induced cellular damage via good ROS scavenging property.
价 格:¥电议型 号:T9560产 地:中国大陆
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T60086TTBK1-IN-2
TTBK1-IN-2 is an inhibitor of Tau-Tubulin kinase (TTBK1) with IC50s of 0.24 and 4.22 ?M. TTBK1-IN-2 reduces TDP-43 phosphorylation both in cell cultures and the spinal cord of transgenic TDP-43 mice.
价 格:¥电议型 号:T60086产 地:中国大陆