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T9552BAZ1A-IN-1leukemia,breast cancer,Epigenetic Reader Domain,BAZ1A IN 1,cancer,ZR-75–30,BAZ1A,BAZ1AIN1,
BAZ1A-IN-1 is a potent BAZ1A inhibitor with the KD value of 0.52 μM for the BAZ1A bromodomain. BAZ1A-IN-1 shows good anti-survival activity against cancer cell lines with high BAZ1A expression, but weak or no activity against cancer cells with low BAZ1A expression.
价 格:¥电议型 号:T9552产 地:中国大陆
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T6500Ferrostatin-1ROS,inhibit,Fer1,cell,neurotoxicity,cytosolic,Ferrostatin1,Fungal,antifungal,antioxidan
Ferrostatin-1 is a potent ferroptosis inhibitor (EC50: 60 nM).
价 格:¥电议型 号:T6500产 地:中国大陆
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T9565OSBPL7-IN-1OSBPL7,orally active,ABCA1,OSBPL7 IN 1,Inhibitor,OSBPL-7-IN-1,OSBPL7IN1,inhibit
OSBPL7-IN-1 is an orally active inhibitor of oxysterol binding protein like 7 (OSBPL7). OSBPL7-IN-1 promotes an increase of ABCA1 at the plasma membrane without affecting mRNA expression[1].
价 格:¥电议型 号:T9565产 地:中国大陆
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T38905FATP1-IN-1FATP1 IN 1,FATP1IN1,FATP-1-IN-1
FATP1-IN-1 is a fatty acid transport protein 1 (FATP1) inhibitor. FATP1-IN-1 is an inhibition of recombinant human or mouse acyl-CoA synthetase activity of FATP1, with the IC 50 values of 0.046 μM or 0.60 μM, respectively.
价 格:¥电议型 号:T38905产 地:中国大陆
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T9394CHIKV-IN-2Dihydroorotate Dehydrogenase,CHIKV,DHODH,virus,inhibit,CHIKV IN 2,Chikungunya,Inhibitor,CH
CHIKV-IN-2 shows inhibitory activity against a cellular target Dihydroorotate Dehydrogenase (DHODH), which interacts with various viruses and regulate their replication via depleting intracellular pyrimidine pools. Therefore, CHIKV-IN-2 is a potent inhibitor against Chikungunya virus (CHIKV), with excellent cellular antiviral activity (EC90=270 nM) and improved liver microsomal stability[1].
价 格:¥电议型 号:T9394产 地:中国大陆
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T10032COX-2-IN-2COX2IN2,COX 2 IN 2
COX-2-IN-2 is a selective and inducible COX2 inhibitor with an IC50 of 0.24 μM. COX-2-IN-1 is an anti-inflammatory compound with anti-inflammatory and analgesic activities
价 格:¥电议型 号:T10032产 地:中国大陆
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T9105NF-κB-IN-1pathway,4-arylidene,Inhibitor,inhibit,IKK,crucumin,cancer,A549,NFκBIN1,I kappa B kinase,si
NF-κB-IN-1 is a potent NF-κB signaling pathway inhibitor. It is a 4-arylidene crucumin analogue. NF-κB-IN-1 directly inhibits IKK to block NF-κB activation. NF-κB-IN-1 effectively inhibits the viability of lung cancer cells and attenuates the clonogenic activity of A549 cells.
价 格:¥电议型 号:T9105产 地:中国大陆
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T67756ISRIB-A15
ISRIB-A15 is an potent inhibitor of the integrated stress response with an EC50 of 0.8 nM.
价 格:¥电议型 号:T67756产 地:中国大陆
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T9648SIRT1-IN-1inhibit,Cytomegalovirus,CMV,antiviral,indole,Inhibitor,Sirtuin,SIRT1IN1,SIRT1 IN 1
SIRT1-IN-1 is a selective inhibitor of SIRT1 with an IC50 of 205 nM. SIRT1-IN-1 is an inhibitor of cytomegalovirus (CMV) with antiviral activity.
价 格:¥电议型 号:T9648产 地:中国大陆
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T62404SHMT-IN-2
SHMT-IN-2 is a stereo specific inhibitor of human SHMT1/2 with IC50 values of 13 nM and 66 nM for SHMT1 and SHMT2, respectively. SHMT-IN-2 can block the growth of many human cancer cells, and has sensitivity for B-cell lymphomas.
价 格:¥电议型 号:T62404产 地:中国大陆
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T8636Ibrutinib deacryloylpiperidineBtk,Bruton tyrosine kinase,Inhibitor,inhibit,Ibrutinib deacryloylpiper
Ibrutinib deacryloylpiperidine is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor with an IC50 of 0.5 nM.
价 格:¥电议型 号:T8636产 地:中国大陆
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T12395PDE9-IN-1PDE-9-IN-1,PDE9IN1,PDE9 IN 1
PDE9-IN-1 is a selective and orally bioavailable Inhibitor of PDE9A(IC50 of 8.7 nM).
价 格:¥电议型 号:T12395产 地:中国大陆
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T6330LinperlisibPI3Kδ-IN-2
PI3Kδ-IN-2 is a potent and selective inhibitor of PI3Kδ
价 格:¥电议型 号:T6330产 地:中国大陆
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T63293-Aminobenzamide3-AB;INO 1001;3-ABA;INO1001;INO-1001;PARP-IN-1
INO-1001 is an effective inhibitor of PARP (IC50<50 nM in CHO cells) and a mediator of oxidant-induced myocyte dysfunction during reperfusion.
价 格:¥电议型 号:T6329产 地:中国大陆
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T5996CB1-IN-11-(2,4-二氯苯基)-N-1-哌啶基-4-[[(1-吡咯烷基磺酰基)氨基]甲基]-5-[5-[2-[4-(三氟甲基)苯基]乙炔基]-2-噻吩基]-1H-吡唑-3-甲酰胺;DBPR2
CB1-IN-1 is a peripherally restricted CB1R antagonist, for CB1R and CB2R with Ki of 0.3 nM and 21 nM,respectively.
价 格:¥电议型 号:T5996产 地:中国大陆
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T5535ERK5-IN-2
ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50s of 0.82 μM, 3 μM for ERK5 and ERK5 MEF2D, respectively.
价 格:¥电议型 号:T5535产 地:中国大陆
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T5485OSU-T315OSU-T315 (1,5-regioisomer);ILK-IN-2
OSU-T315 (1,5-regioisomer) is a ILK inhibitor.
价 格:¥电议型 号:T5485产 地:中国大陆
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T5466Tyrosine kinase-IN-1
Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor(KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively)
价 格:¥电议型 号:T5466产 地:中国大陆
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T5402DDR1-IN-2DDR1 inhibitor 7rh
DDR1-IN-2 (DDR1 inhibitor 7rh) is a potent, selective, ATP-competitive Discoidin domain receptor 1 (DDR1) inhibitor (IC50: 6.8 nM in cell-free kinase assays).
价 格:¥电议型 号:T5402产 地:中国大陆